Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(6-benzyl-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
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 PubChem ID
CID: 127039612
Canonical SMILES
NC(=O)C1CCN(CC1)c1nc(nc2CCN(Cc3ccccc3)Cc12)-c1ccccn1
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Compound Formula C25H28N6O
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o-
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1412.54 nM
   TI
   LI
   LO
   TS
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 1400 nM