Brief Information of the Compound and Protein
Compound Name
(7-fluoro-10-methyl-2,4,5,6-tetrahydro-1H-azepino[4,5-b]indol-3-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
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Canonical SMILES
Cc1ccc(F)c2[nH]c3CCN(CCc3c12)C(=O)c1cc([nH]n1)C(F)(F)F
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Compound Formula C18H16F4N4O
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 2300 nM
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