Brief Information of the Compound and Protein
Compound Name
N-[12-[3-(dimethylamino)anilino]-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2,2-dimethylpropanamide
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PubChem ID
CID: 118710758
Canonical SMILES
CN(C)c1cccc(Nc2nc-3c(CCCc4nc(NC(=O)C(C)(C)C)sc-34)s2)c1
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Compound Formula C22H27N5OS2
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
IC50 = 2200 nM
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