Brief Information of the Compound and Protein
Compound Name
2-[5-(trifluoromethyl)-1H-pyrazole-3-carbonyl]-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-carbonitrile
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PubChem ID
CID: 151893480
Canonical SMILES
FC(F)(F)c1cc(n[nH]1)C(=O)N1CCc2[nH]c3ccc(cc3c2C1)C#N
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Compound Formula C17H12F3N5O
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 1900 nM
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