Brief Information of the Compound and Protein
Compound Name
methyl 1-[2-(5-chloro-2-methoxyanilino)-4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-5-yl]triazole-4-carboxylate
    Show/Hide
PubChem ID
CID: 66554124
SID: 152160820
Canonical SMILES
COC(=O)c1cn(nn1)-c1sc(Nc2cc(Cl)ccc2OC)nc1-c1sc(NC(=O)C(C)(C)C)nc1C
    Show/Hide
Compound Formula C23H24ClN7O4S2
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 4600 nM
   TI
   LI
   LO
   TS