Brief Information of the Compound and Protein
Compound Name
 Compound Info 
12,14-dimethyl-9-(5-methylfuran-2-yl)-4-nitro-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-13,15-dione
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 PubChem ID
CID: 53391742
SID: 125319975
Canonical SMILES
Cc1ccc(o1)C1Oc2ccc(cc2-n2c1c1n(C)c(=O)n(C)c(=O)c1c2-c1ccccc1)[N+]([O-])=O
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Compound Formula C26H20N4O6
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  2
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
   TI
   LI
   LO
   TS