Brief Information of the Compound and Protein
Compound Name
N-[3-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]propyl]pyridine-3-carboxamide
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PubChem ID
CID: 44754025
SID: 135667212
Canonical SMILES
Cc1cc(C)c2cc(C#N)c(NCCCNC(=O)c3cccnc3)nc2c1
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Compound Formula C21H21N5O
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o- Homo sapiens (Human)  1
1
EC50 = 3019.95 nM
   TI
   LI
   LO
   TS
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 3000 nM
   TI
   LI
   LO
   TS