Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7-dihydro-5H-5,7,9,11a-tetraaza-benzo[a]fluorene-8,10-dione
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 PubChem ID
CID: 16016583
SID: 89443687
Canonical SMILES
Cc1ccc(o1)C1Nc2ccccc2-n2c1c1n(C)c(=O)n(C)c(=O)c1c2-c1ccccc1
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Compound Formula C26H22N4O3
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  4
1
IC50 = 90 nM
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
   TI
   LI
   LO
   TS
3
IC50 = 250 nM
   TI
   LI
   LO
   TS
4
IC50 = 800 nM
   TI
   LI
   LO
   TS
CL000805 HBE1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS
CL000451 T84
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS