Brief Information of the Compound and Protein
Compound Name
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
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PubChem ID
CID: 5280961
SID: 49684188
Canonical SMILES
Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O
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Compound Formula C15H10O5
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 8200 nM
   TI
   LI
   LO
   TS
2
EC50 = 8480 nM
   TI
   LI
   LO
   TS
CL000259 FRT Rattus norvegicus (Rat)  2
1
EC50 = 6170 nM
   TI
   LI
   LO
   TS
2
EC50 = 14200 nM
   TI
   LI
   LO
   TS