Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[5-[2-(5-chloro-2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide
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 PubChem ID
CID: 1144671
SID: 17419069
Canonical SMILES
COc1ccc(Cl)cc1Nc1nc(cs1)-c1sc(NC(=O)c2ccccc2)nc1C
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Compound Formula C21H17ClN4O2S2
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o-
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1096.48 nM
   TI
   LI
   LO
   TS
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  3
1
EC50 = 1100 nM
   TI
   LI
   LO
   TS
2
IC50 = 6000 nM
   TI
   LI
   LO
   TS
3
Kd = 900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 <= 2800 nM