Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ethyl 9-(5-bromofuran-2-yl)-12,14-dimethyl-13,15-dioxo-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylate
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 PubChem ID
CID: 53391745
SID: 125319978
Canonical SMILES
CCOC(=O)c1ccc2OC(c3ccc(Br)o3)c3n(c(-c4ccccc4)c4c3n(C)c(=O)n(C)c4=O)-c2c1
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Compound Formula C28H22BrN3O6
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  2
1
IC50 = 25 nM
   TI
   LI
   LO
   TS
2
IC50 = 50 nM
   TI
   LI
   LO
   TS