General Information of the Compound
Compound ID
CP0476844
Compound Name
2-N,2-N-diethyl-4-N-(3-nitrophenyl)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine
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Structure
Formula
C16H18F4N6O3
Molecular Weight
418.351
Canonical SMILES
CCN(CC)c1nc(Nc2cccc(c2)[N+]([O-])=O)nc(OCC(F)(F)C(F)F)n1
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InChI
InChI=1S/C16H18F4N6O3/c1-3-25(4-2)14-22-13(21-10-6-5-7-11(8-10)26(27)28)23-15(24-14)29-9-16(19,20)12(17)18/h5-8,12H,3-4,9H2,1-2H3,(H,21,22,23,24)
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InChIKey
NOVSXRLYPRKYBY-UHFFFAOYSA-N
Physicochemical Property
logP
3.6488
Rotatable Bonds
10
Heavy Atom Count
29
Polar Areas
106.31
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 129304814
ChEMBL ID
CHEMBL4071412
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02042, Cystic fibrosis transmembrane conductance regulator
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 1200 nM
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