Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-cyclohexyloxy-2-[1-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]ethyl]quinazoline
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 PubChem ID
CID: 11957831
SID: 17405951
Canonical SMILES
COc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)c1nc(OC2CCCCC2)c2ccccc2n1
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Compound Formula C27H34N4O4S
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o-
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2187.76 nM
   TI
   LI
   LO
   TS
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 2200 nM
   TI
   LI
   LO
   TS