Brief Information of the Compound and Protein
Compound Name
(+/-)-(6-Fluoro-3,9-dimethyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]-indol-2-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
    Show/Hide
Canonical SMILES
Cc1ccc(F)c2[nH]c3c(c12)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)C(C)C3
    Show/Hide
Compound Formula C18H16F4N4O
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 22 nM
   TI
   LI
   LO
   TS