Brief Information of the Compound and Protein
Compound Name
N-[4-nitro-2-(12-oxo-4-oxa-1,10-diazatricyclo[7.3.1.05,13]trideca-5,7,9(13),10-tetraen-11-yl)phenyl]acetamide
    Show/Hide
PubChem ID
CID: 129286545
Canonical SMILES
CC(=O)Nc1ccc(cc1-c1nc2cccc3OCCn(c23)c1=O)[N+]([O-])=O
    Show/Hide
Compound Formula C18H14N4O5
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 820 nM
   TI
   LI
   LO
   TS