Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2,2-dimethylpropanamide
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 PubChem ID
CID: 25130495
SID: 56454855
Canonical SMILES
COc1ccc(Cl)cc1Nc1nc-2c(CCCc3nc(NC(=O)C(C)(C)C)sc-23)s1
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Compound Formula C21H23ClN4O2S2
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  2
1
EC50 = 300 nM
   TI
   LI
   LO
   TS
2
IC50 = 2300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 300 nM