Brief Information of the Compound and Protein
Compound Name
1-[(5-chloro-2-methoxyphenyl)methyl]-5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-N-(2-hydroxyethyl)pyrazole-3-carboxamide
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PubChem ID
CID: 46888194
Canonical SMILES
COc1ccc(Cl)cc1Cn1nc(cc1-c1sc(NC(=O)C(C)(C)C)nc1C)C(=O)NCCO
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Compound Formula C23H28ClN5O4S
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 3000 nM
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