Brief Information of the Compound and Protein
Compound Name
methyl 4-[[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]amino]-4-oxobutanoate
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PubChem ID
CID: 118710754
Canonical SMILES
COC(=O)CCC(=O)Nc1nc2CCCc3sc(Nc4cc(Cl)ccc4OC)nc3-c2s1
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Compound Formula C21H21ClN4O4S2
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
IC50 = 8800 nM
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