All Bioactivity

Brief Information of the Cell Line and Protein

Cell Line ID: CL000006 , HEK293

Cell Line Info

Synonyms	Hek293 HEK-293 HEK/293 HEK 293 HEK;293 293 293 HEK 293 Ad5 Graham 293 Graham-293 Human Embryonic Kidney 293
Category	Transformed cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0045

Protein ID: PT01670 , Calcitonin gene-related peptide type 1 receptor

Protein Info

Gene Name	CALCRL
Organism	Homo sapiens, Human
Protein Classification	Membrane receptor
Uniprot ID	Q16602

Table of Molecular Bioactivities Related to the Cell Line and Protein

Cell Line ID: CL000006

Cell Line Info

Protein ID: PT01670

Protein Info

Compound ID	Compound Name	Compound Formula
CP0532137 Compound Info	ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 Show/Hide	C163H269N51O49S2	1
1	EC50 = 0.2 nM Bioactivity Info	TI LI LO TS
CP0430652 Compound Info	(R)-1-((2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-2-yl)methyl)-1H-imidazo[1,5,4-de]quinoxaline-2,5(4H,6H)-dione Show/Hide	C28H20N6O3	3
1	IC50 = 0.077 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.5 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.023 nM Bioactivity Info	TI LI LO TS
CP0531213 Compound Info	2-((S)-6-(2,6-difluorophenyl)-3,3-dimethyl-2-oxopiperidin-1-yl)-N-((S)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)acetamide Show/Hide	C30H28F2N4O3	2
1	IC50 = 0.12 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.035 nM Bioactivity Info	TI LI LO TS
CP0452896 Compound Info	(S)-2-(2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5,4-de]quinoxalin-1-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)acetamide Show/Hide	C26H20N6O4	4
1	IC50 = 0.28 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.62 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.039 nM Bioactivity Info	TI LI LO TS
4	Ki = 0.04 nM Bioactivity Info	TI LI LO TS
CP0376357 Compound Info	2a-methyl-1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-2-yl)methyl)-1,2,2a,3-tetrahydropyrrolo[4,3,2-de]quinolin-4(5H)-one Show/Hide	C30H25N5O2	3
1	IC50 = 0.52 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0404774 Compound Info	(S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-2,3-dihydropyrrolo[4,3,2-de]quinolin-5(1H)-yl)acetamide Show/Hide	C27H21N5O3	3
1	IC50 = 0.61 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0494271 Compound Info	2a-(aminomethyl)-1-(((S)-2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-2-yl)methyl)-2a,3-dihydropyrrolo[4,3,2-de]quinoline-2,4(1H,5H)-dione Show/Hide	C30H24N6O3	2
1	IC50 = 0.62 nM Bioactivity Info	TI LI LO TS
2	Ki = 0.13 nM Bioactivity Info	TI LI LO TS
CP0389736 Compound Info	2a-ethyl-1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-2-yl)methyl)-1,2,2a,3-tetrahydropyrrolo[4,3,2-de]quinolin-4(5H)-one Show/Hide	C31H27N5O2	3
1	IC50 = 0.68 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.5 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.072 nM Bioactivity Info	TI LI LO TS
CP0400281 Compound Info	1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-2-yl)methyl)-1,2,2a,3-tetrahydropyrrolo[4,3,2-de]quinolin-4(5H)-one Show/Hide	C29H23N5O2	3
1	IC50 = 0.86 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.55 nM Bioactivity Info	TI LI LO TS
CP0438067 Compound Info	(S)-2-(5,7-dimethyl-2-oxo-3-(2-oxo-2-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-ylamino)ethyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N,N-dimethylacetamide Show/Hide	C30H30N6O4	3
1	IC50 = 0.87 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.21 nM Bioactivity Info	TI LI LO TS
CP0844969 Compound Info	(R)-2-(6,8-dimethyl-2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5,4-de]quinoxalin-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C25H24N6O5	6
1	IC50 = 0.88 nM Bioactivity Info	TI LI LO TS
2	IC50 = 13 nM Bioactivity Info	TI LI LO TS
3	IC50 = 31 nM Bioactivity Info	TI LI LO TS
4	IC50 = 220 nM Bioactivity Info	TI LI LO TS
5	Ki = 0.23 nM Bioactivity Info	TI LI LO TS
6	Ki = 7.1 nM Bioactivity Info	TI LI LO TS
CP0376356 Compound Info	(R)-6-methyl-1-((2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-2-yl)methyl)-1H-imidazo[1,5,4-de]quinoxaline-2,5(4H,6H)-dione Show/Hide	C29H22N6O3	3
1	IC50 = 1.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 95 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.41 nM Bioactivity Info	TI LI LO TS
CP0460401 Compound Info	2-(2a-methyl-4-oxo-2a,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolin-1(2H)-yl)-N-((S)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)acetamide Show/Hide	C28H25N5O3	3
1	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6.5 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.28 nM Bioactivity Info	TI LI LO TS
CP0372440 Compound Info	(S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-3-(pyrimidin-4-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C28H21N7O3	3
1	IC50 = 1.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 35 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.61 nM Bioactivity Info	TI LI LO TS
CP0430651 Compound Info	(S)-1-((3'-methyl-2',5'-dioxo-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2-yl)methyl)-1H-imidazo[1,5,4-de]quinoxaline-2,5(4H,6H)-dione Show/Hide	C25H20N6O4	3
1	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 14 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.3 nM Bioactivity Info	TI LI LO TS
CP0024947 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C26H27F5N6O3	5
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
3	IC50 = 11 nM Bioactivity Info	TI LI LO TS
4	Ki = 0.77 nM Bioactivity Info	TI LI LO TS
5	Ki = 0.8 nM Bioactivity Info	TI LI LO TS
CP0486038 Compound Info	(4'S)-3'-methyl-2-((2a-methyl-4-oxo-2a,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolin-1(2H)-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2',5'-dione Show/Hide	C27H25N5O3	3
1	IC50 = 2.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6.5 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.52 nM Bioactivity Info	TI LI LO TS
CP0387520 Compound Info	(R)-2-(2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5,4-de]quinoxalin-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C23H20N6O5	3
1	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5.4 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.51 nM Bioactivity Info	TI LI LO TS
CP0447913 Compound Info	(S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-3-(tetrahydro-2H-thiopyran-4-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C29H27N5O3S	3
1	IC50 = 2.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 24 nM Bioactivity Info	TI LI LO TS
3	Ki = 0.87 nM Bioactivity Info	TI LI LO TS
CP0500600 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2-oxospiro[1H-pyrido[2,3-d][1,3]oxazine-4,4'-piperidine]-1'-carboxamide Show/Hide	C26H26F5N5O4	3
1	IC50 = 2.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 13 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
CP0404776 Compound Info	2-(10-oxo-3,9-diazatricyclo[6.4.1.04,13]trideca-4,6,8(13)-trien-3-yl)-N-[(2S)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C28H25N5O3	3
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 23 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.1 nM Bioactivity Info	TI LI LO TS
CP0388295 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,4'-piperidine]-1'-carboxamide Show/Hide	C26H26F5N5O3	3
1	IC50 = 3.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 11 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0485236 Compound Info	(S)-2-(1-methyl-2-oxo-2,3-dihydropyrrolo[4,3,2-de]quinolin-5(1H)-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)acetamide Show/Hide	C28H23N5O3	3
1	IC50 = 4.1 nM Bioactivity Info	TI LI LO TS
2	IC50 = 67 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0430650 Compound Info	(R)-2-((2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one Show/Hide	C28H22N4O2	3
1	IC50 = 4.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 81 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0372073 Compound Info	2-[2-oxo-3-(oxolan-3-yl)benzimidazol-1-yl]-N-[(2S)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C28H25N5O4	3
1	IC50 = 5.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 27 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0505781 Compound Info	(R)-methyl 2-(5,7-dimethyl-3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetate Show/Hide	C26H27N5O6	3
1	IC50 = 5.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 150 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.1 nM Bioactivity Info	TI LI LO TS
CP0372568 Compound Info	(S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-1-yl)acetamide Show/Hide	C29H26N4O4	3
1	IC50 = 5.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 39 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0404777 Compound Info	2-(10-oxo-3,9-diazatricyclo[6.5.1.04,14]tetradeca-4,6,8(14)-trien-3-yl)-N-[(2S)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C29H27N5O3	3
1	IC50 = 7.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 37 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
CP0429758 Compound Info	(4'S)-2-((2a-ethyl-4-oxo-2a,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolin-1(2H)-yl)methyl)-3'-methyl-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2',5'-dione Show/Hide	C28H27N5O3	3
1	IC50 = 7.2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 44 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0400280 Compound Info	(4'S)-3'-methyl-2-((4-oxo-2a,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolin-1(2H)-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2',5'-dione Show/Hide	C26H23N5O3	3
1	IC50 = 7.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 43 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.5 nM Bioactivity Info	TI LI LO TS
CP0423399 Compound Info	(S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C29H22N6O3	3
1	IC50 = 8.6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 420 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.3 nM Bioactivity Info	TI LI LO TS
CP0401167 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyrimidin-4-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C25H21N7O4	3
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
2	IC50 = 74 nM Bioactivity Info	TI LI LO TS
3	Ki = 16 nM Bioactivity Info	TI LI LO TS
CP0372572 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(3,4,6-trimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C24H25N5O4	4
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
2	IC50 = 370 nM Bioactivity Info	TI LI LO TS
3	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
4	Ki = 2.7 nM Bioactivity Info	TI LI LO TS
CP0443569 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2-oxospiro[1,3-dihydro-1,8-naphthyridine-4,4'-piperidine]-1'-carboxamide Show/Hide	C27H28F5N5O3	2
1	IC50 = 11 nM Bioactivity Info	TI LI LO TS
2	Ki = 3.5 nM Bioactivity Info	TI LI LO TS
CP0401168 Compound Info	(R)-2-(5,7-dimethyl-3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N,N-dimethylacetamide Show/Hide	C27H30N6O5	4
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 14 nM Bioactivity Info	TI LI LO TS
3	IC50 = 23 nM Bioactivity Info	TI LI LO TS
4	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0498977 Compound Info	2-{9-methyl-2,10-dioxo-1,3,9-triazatricyclo[6.5.1.0^{4,14}]tetradeca-4(14),5,7-trien-3-yl}-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-6'-yl]acetamide Show/Hide	C26H26N6O5	3
1	IC50 = 12 nM Bioactivity Info	TI LI LO TS
2	IC50 = 13 nM Bioactivity Info	TI LI LO TS
3	Ki = 2.2 nM Bioactivity Info	TI LI LO TS
CP0372570 Compound Info	(R)-2-(3-(2-amino-2-oxoethyl)-4,6-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C25H26N6O5	3
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
2	IC50 = 140 nM Bioactivity Info	TI LI LO TS
3	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
CP0374120 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(3-methyl-6-oxo-1H-pyridazin-5-yl)piperidine-1-carboxamide Show/Hide	C25H28F5N5O3	3
1	IC50 = 13 nM Bioactivity Info	TI LI LO TS
2	IC50 = 21 nM Bioactivity Info	TI LI LO TS
3	Ki = 6.6 nM Bioactivity Info	TI LI LO TS
CP0401919 Compound Info	2-{2,10-dioxo-1,3,9-triazatricyclo[6.5.1.0^{4,14}]tetradeca-4(14),5,7-trien-3-yl}-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-6'-yl]acetamide Show/Hide	C25H24N6O5	3
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
2	IC50 = 21 nM Bioactivity Info	TI LI LO TS
3	Ki = 4.7 nM Bioactivity Info	TI LI LO TS
CP0542118 Compound Info	(R)-2-(4,6-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C23H23N5O4	2
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
2	Ki = 5.5 nM Bioactivity Info	TI LI LO TS
CP0374121 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-oxo-2-phenyl-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxamide Show/Hide	C28H28F5N5O3	3
1	IC50 = 23 nM Bioactivity Info	TI LI LO TS
2	IC50 = 871 nM Bioactivity Info	TI LI LO TS
3	Ki = 30 nM Bioactivity Info	TI LI LO TS
CP0372101 Compound Info	(R)-N,N-dimethyl-4-(3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)butanamide Show/Hide	C27H30N6O5	3
1	IC50 = 24 nM Bioactivity Info	TI LI LO TS
2	IC50 = 30 nM Bioactivity Info	TI LI LO TS
3	Ki = 9.6 nM Bioactivity Info	TI LI LO TS
CP0471936 Compound Info	(R)-2-(4,6-dimethyl-2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C28H26N6O4	3
1	IC50 = 26 nM Bioactivity Info	TI LI LO TS
2	IC50 = 426 nM Bioactivity Info	TI LI LO TS
3	Ki = 4.3 nM Bioactivity Info	TI LI LO TS
CP0372068 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-3-(tetrahydro-2H-thiopyran-4-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C26H27N5O4S	3
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
2	IC50 = 220 nM Bioactivity Info	TI LI LO TS
3	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0431365 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(6-methyl-2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5,4-de]quinoxalin-1-yl)acetamide Show/Hide	C24H22N6O5	3
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
2	IC50 = 220 nM Bioactivity Info	TI LI LO TS
3	Ki = 7.1 nM Bioactivity Info	TI LI LO TS
CP0430653 Compound Info	(S)-6-methyl-1-((3'-methyl-2',5'-dioxo-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2-yl)methyl)-1H-imidazo[1,5,4-de]quinoxaline-2,5(4H,6H)-dione Show/Hide	C26H22N6O4	3
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
3	Ki = 3 nM Bioactivity Info	TI LI LO TS
CP0460400 Compound Info	2-((S)-5-methyl-4-oxo-2a,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolin-1(2H)-yl)-N-((S)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)acetamide Show/Hide	C28H25N5O3	3
1	IC50 = 37 nM Bioactivity Info	TI LI LO TS
2	IC50 = 530 nM Bioactivity Info	TI LI LO TS
3	Ki = 9.7 nM Bioactivity Info	TI LI LO TS
CP0372435 Compound Info	(R)-2-(4-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C21H18ClN5O4	3
1	IC50 = 42 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2000 nM Bioactivity Info	TI LI LO TS
3	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0372441 Compound Info	(R)-4-(3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)butanamide Show/Hide	C25H26N6O5	3
1	IC50 = 43 nM Bioactivity Info	TI LI LO TS
2	IC50 = 76 nM Bioactivity Info	TI LI LO TS
3	Ki = 13 nM Bioactivity Info	TI LI LO TS
CP0493698 Compound Info	(R)-2-(5,7-dimethyl-3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetic acid Show/Hide	C25H25N5O6	3
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4100 nM Bioactivity Info	TI LI LO TS
3	Ki = 26 nM Bioactivity Info	TI LI LO TS
CP0381135 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(6-oxo-1H-pyridazin-5-yl)piperidine-1-carboxamide Show/Hide	C24H26F5N5O3	3
1	IC50 = 44 nM Bioactivity Info	TI LI LO TS
2	IC50 = 112 nM Bioactivity Info	TI LI LO TS
3	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0134898 Compound Info	(R)-4-(2-oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl)-N-(2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)piperidine-1-carboxamide Show/Hide	C29H26F3N7O3	3
1	IC50 = 49 nM Bioactivity Info	TI LI LO TS
2	IC50 = 730 nM Bioactivity Info	TI LI LO TS
3	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0390135 Compound Info	(S)-3'-methyl-2-((2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2',5'-dione Show/Hide	C25H22N4O3	3
1	IC50 = 50 nM Bioactivity Info	TI LI LO TS
2	IC50 = 850 nM Bioactivity Info	TI LI LO TS
3	Ki = 8.9 nM Bioactivity Info	TI LI LO TS
CP0388296 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-1,3-dioxo-2,8-diazaspiro[4.5]decane-8-carboxamide Show/Hide	C23H25F5N4O4	3
1	IC50 = 55 nM Bioactivity Info	TI LI LO TS
2	IC50 = 95 nM Bioactivity Info	TI LI LO TS
3	Ki = 41 nM Bioactivity Info	TI LI LO TS
CP0387514 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-1-yl)acetamide Show/Hide	C26H26N4O5	3
1	IC50 = 57 nM Bioactivity Info	TI LI LO TS
2	IC50 = 160 nM Bioactivity Info	TI LI LO TS
3	Ki = 35 nM Bioactivity Info	TI LI LO TS
CP0509265 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(4-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C22H21N5O4	2
1	IC50 = 59 nM Bioactivity Info	TI LI LO TS
2	Ki = 41 nM Bioactivity Info	TI LI LO TS
CP0521351 Compound Info	(R)-2-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C21H18ClN5O4	3
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
2	IC50 = 490 nM Bioactivity Info	TI LI LO TS
3	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0374119 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2-oxospiro[1H-3,1-benzoxazine-4,4'-piperidine]-1'-carboxamide Show/Hide	C27H27F5N4O4	3
1	IC50 = 60 nM Bioactivity Info	TI LI LO TS
2	IC50 = 792 nM Bioactivity Info	TI LI LO TS
3	Ki = 46 nM Bioactivity Info	TI LI LO TS
CP0401977 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-(oxolan-3-yl)benzimidazol-1-yl]acetamide Show/Hide	C25H25N5O5	3
1	IC50 = 61 nM Bioactivity Info	TI LI LO TS
2	IC50 = 170 nM Bioactivity Info	TI LI LO TS
3	Ki = 20 nM Bioactivity Info	TI LI LO TS
CP0514199 Compound Info	(R)-2-(6-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C21H18ClN5O4	2
1	IC50 = 64 nM Bioactivity Info	TI LI LO TS
2	Ki = 9.5 nM Bioactivity Info	TI LI LO TS
CP0442116 Compound Info	(3S)-4-[[(2S)-1-[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]hydrazinyl]-3-methyl-1-oxobutan-2-yl]amino]-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoic acid Show/Hide	C59H81N13O14	1
1	IC50 = 67.61 nM Bioactivity Info	TI LI LO TS
CP0372569 Compound Info	(S)-methyl 2-(5,7-dimethyl-3-(2-((R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propanoate Show/Hide	C27H29N5O6	2
1	IC50 = 72 nM Bioactivity Info	TI LI LO TS
2	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0387517 Compound Info	(R)-2-(4-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C21H18FN5O4	3
1	IC50 = 76 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
3	Ki = 32 nM Bioactivity Info	TI LI LO TS
CP0179406 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C26H22N6O4	4
1	IC50 = 78 nM Bioactivity Info	TI LI LO TS
2	IC50 = 530 nM Bioactivity Info	TI LI LO TS
3	Ki = 20 nM Bioactivity Info	TI LI LO TS
4	Ki = 21 nM Bioactivity Info	TI LI LO TS
CP0447578 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decane-8-carboxamide Show/Hide	C22H24F5N5O4	3
1	IC50 = 94 nM Bioactivity Info	TI LI LO TS
2	IC50 = 122 nM Bioactivity Info	TI LI LO TS
3	Ki = 46 nM Bioactivity Info	TI LI LO TS
CP0372100 Compound Info	(R)-2-(5-methoxy-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C22H21N5O5	3
1	IC50 = 98 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4500 nM Bioactivity Info	TI LI LO TS
3	Ki = 62 nM Bioactivity Info	TI LI LO TS
CP0383512 Compound Info	(3S)-4-[[(2S)-1-[[(3S,6S,8aS)-3-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-5-oxo-2,3,6,7,8,8a-hexahydro-1H-indolizin-6-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoic acid Show/Hide	C62H84N12O14	1
1	IC50 = 107.15 nM Bioactivity Info	TI LI LO TS
CP0409265 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C21H19N5O4	4
1	IC50 = 110 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
3	Ki = 38 nM Bioactivity Info	TI LI LO TS
4	Ki = 43 nM Bioactivity Info	TI LI LO TS
CP0505021 Compound Info	(R)-N,N-dimethyl-3-(3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propanamide Show/Hide	C26H28N6O5	2
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
2	Ki = 36 nM Bioactivity Info	TI LI LO TS
CP0388297 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-1-oxo-3-phenyl-2,8-diazaspiro[4.5]decane-8-carboxamide Show/Hide	C29H31F5N4O3	3
1	IC50 = 120 nM Bioactivity Info	TI LI LO TS
2	IC50 = 692 nM Bioactivity Info	TI LI LO TS
3	Ki = 380 nM Bioactivity Info	TI LI LO TS
CP0521350 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(6-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C22H21N5O4	2
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
2	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0505027 Compound Info	(R)-2-(3-(2-amino-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C23H22N6O5	3
1	IC50 = 130 nM Bioactivity Info	TI LI LO TS
2	IC50 = 150 nM Bioactivity Info	TI LI LO TS
3	Ki = 37 nM Bioactivity Info	TI LI LO TS
CP0372099 Compound Info	(R)-2-(5-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C21H18FN5O4	2
1	IC50 = 150 nM Bioactivity Info	TI LI LO TS
2	Ki = 18 nM Bioactivity Info	TI LI LO TS
CP0387518 Compound Info	(R)-2-(4-methoxy-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C22H21N5O5	3
1	IC50 = 260 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4400 nM Bioactivity Info	TI LI LO TS
3	Ki = 26 nM Bioactivity Info	TI LI LO TS
CP0505024 Compound Info	(R)-N,N-dimethyl-2-(3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C25H26N6O5	2
1	IC50 = 280 nM Bioactivity Info	TI LI LO TS
2	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0424964 Compound Info	2-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]amino]acetic acid Show/Hide	C59H81N13O14	1
1	IC50 = 380.19 nM Bioactivity Info	TI LI LO TS
CP0372571 Compound Info	(R)-2-(7-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C21H18ClN5O4	2
1	IC50 = 450 nM Bioactivity Info	TI LI LO TS
2	Ki = 250 nM Bioactivity Info	TI LI LO TS
CP0378822 Compound Info	Azafvptdvgpfaf-Nh2 Show/Hide	C59H81N13O14	1
1	IC50 = 588.84 nM Bioactivity Info	TI LI LO TS
CP0498975 Compound Info	(R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(5-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C22H21N5O4	2
1	IC50 = 590 nM Bioactivity Info	TI LI LO TS
2	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0442115 Compound Info	(3S)-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoic acid Show/Hide	C60H82N12O14	1
1	IC50 = 707.95 nM Bioactivity Info	TI LI LO TS
CP0527940 Compound Info	(3S)-4-[[(2S)-1-[[2-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-[[(2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-4-oxobutanoic acid Show/Hide	C46H64N10O12	1
1	IC50 = 776.25 nM Bioactivity Info	TI LI LO TS
CP0418981 Compound Info	(R)-2-(6-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C21H18FN5O4	3
1	IC50 = 780 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1200 nM Bioactivity Info	TI LI LO TS
3	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0418980 Compound Info	(R)-2-(6-methoxy-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)acetamide Show/Hide	C22H21N5O5	2
1	IC50 = 1500 nM Bioactivity Info	TI LI LO TS
2	Ki = 120 nM Bioactivity Info	TI LI LO TS
CP0849950 Compound Info	FVPTDVGPFazaAF-NH2 Show/Hide	C59H81N13O14	1
1	IC50 = 3548.13 nM Bioactivity Info	TI LI LO TS
CP0424963 Compound Info	(3S)-4-[[(2S)-1-[[2-[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrazolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-[[(2S,3R)-3-hydroxy-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]-4-oxobutanoic acid Show/Hide	C45H63N11O12	1
1	IC50 = 4466.84 nM Bioactivity Info	TI LI LO TS
CP0456518 Compound Info	(3S)-4-[[(2S)-1-[[2-[(2S)-2-[[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl-benzylamino]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]-4-oxobutanoic acid Show/Hide	C59H81N13O14	1
1	IC50 = 5754.4 nM Bioactivity Info	TI LI LO TS
CP0387315 Compound Info	2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-3'-yl]acetamide Show/Hide	C32H32F2N6O3	1
1	Ki = 0.017 nM Bioactivity Info	TI LI LO TS
CP0387318 Compound Info	(3S)-3'-[3-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]prop-1-ynyl]spiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-2-one Show/Hide	C33H31F2N5O2	1
1	Ki = 0.019 nM Bioactivity Info	TI LI LO TS
CP0003456 Compound Info	2-[(8R)-8-(3,5-difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C31H29F2N5O3	1
1	Ki = 0.021 nM Bioactivity Info	TI LI LO TS
CP0482478 Compound Info	(3S)-3'-[(E)-3-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]prop-1-enyl]spiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-2-one Show/Hide	C33H33F2N5O2	1
1	Ki = 0.021 nM Bioactivity Info	TI LI LO TS
CP0500995 Compound Info	2-[(6R)-6-(3,5-difluorophenyl)-3,3,4-trimethyl-2-oxopiperazin-1-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C30H29F2N5O3	1
1	Ki = 0.022 nM Bioactivity Info	TI LI LO TS
CP0449907 Compound Info	2-[(6R)-6-(3,5-difluorophenyl)-3,3-dimethyl-2-oxopiperazin-1-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C29H27F2N5O3	1
1	Ki = 0.034 nM Bioactivity Info	TI LI LO TS
CP0504439 Compound Info	N-[[(1R)-2,3-dihydro-1H-inden-1-yl]methyl]-2,2-dimethyl-N-[[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,7'-6,8-dihydrocyclopenta[g]quinoline]-3'-yl]methyl]propanamide Show/Hide	C34H34N4O2	1
1	Ki = 0.037 nM Bioactivity Info	TI LI LO TS
CP0009286 Compound Info	2-[(8R)-8-(3,5-difluorophenyl)-8-methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C32H31F2N5O3	1
1	Ki = 0.04 nM Bioactivity Info	TI LI LO TS
CP0494250 Compound Info	(3S)-3'-[3-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]propyl]spiro[1H-pyrrolo[2,3-b]pyridine-3,6'-5,7-dihydrocyclopenta[b]pyridine]-2-one Show/Hide	C33H35F2N5O2	1
1	Ki = 0.045 nM Bioactivity Info	TI LI LO TS
CP0187326 Compound Info	2-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C33H33F2N5O3	1
1	Ki = 0.046 nM Bioactivity Info	TI LI LO TS
CP0494251 Compound Info	2-[(2R)-2-(3,5-difluorophenyl)-2,4,5,5-tetramethyl-6-oxopiperazin-1-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C31H31F2N5O3	1
1	Ki = 0.056 nM Bioactivity Info	TI LI LO TS
CP0445318 Compound Info	(2R)-5-[(E)-3-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]prop-1-enyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one Show/Hide	C34H34F2N4O2	1
1	Ki = 0.094 nM Bioactivity Info	TI LI LO TS
CP0504438 Compound Info	2,2-dimethyl-N-[[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,7'-6,8-dihydrocyclopenta[g]quinoline]-3'-yl]methyl]-N-[(1R)-1-phenylethyl]propanamide Show/Hide	C32H32N4O2	1
1	Ki = 0.1 nM Bioactivity Info	TI LI LO TS
CP0528282 Compound Info	N-[[(1R)-2,3-dihydro-1H-inden-1-yl]methyl]-2,2-dimethyl-N-[[(2S)-2'-oxospiro[1,3-dihydrocyclopenta[b]quinoline-2,3'-1H-pyrrolo[2,3-b]pyridine]-7-yl]methyl]propanamide Show/Hide	C34H34N4O2	1
1	Ki = 0.11 nM Bioactivity Info	TI LI LO TS
CP0432382 Compound Info	2-[(2R)-2-(3,5-difluorophenyl)-2,5,5-trimethyl-6-oxopiperazin-1-yl]-N-[(2R)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide Show/Hide	C30H29F2N5O3	1
1	Ki = 0.11 nM Bioactivity Info	TI LI LO TS
CP0449906 Compound Info	(2R)-5-[3-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]prop-1-ynyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one Show/Hide	C34H32F2N4O2	1
1	Ki = 0.11 nM Bioactivity Info	TI LI LO TS
CP0473515 Compound Info	N-[(1R)-1-(3,5-difluorophenyl)ethyl]-2,2-dimethyl-N-[[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,7'-6,8-dihydrocyclopenta[g]quinoline]-3'-yl]methyl]propanamide Show/Hide	C32H30F2N4O2	1
1	Ki = 0.12 nM Bioactivity Info	TI LI LO TS
CP0507610 Compound Info	N-[[(1R)-2,3-dihydro-1H-inden-1-yl]methyl]-2,2-dimethyl-N-[[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,7'-6,8-dihydrocyclopenta[b][1,8]naphthyridine]-3'-yl]methyl]propanamide Show/Hide	C33H33N5O2	1
1	Ki = 0.15 nM Bioactivity Info	TI LI LO TS
CP0426939 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-[2-(trifluoromethoxy)ethyl]azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C27H29F5N6O4	1
1	Ki = 0.19 nM Bioactivity Info	TI LI LO TS
CP0485748 Compound Info	N-[(1R)-1-(3,5-difluorophenyl)ethyl]-2,2-dimethyl-N-[2-[[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]propanamide Show/Hide	C27H30F2N4O4	1
1	Ki = 0.26 nM Bioactivity Info	TI LI LO TS
CP0454992 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methoxyethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C27H32F2N6O4	1
1	Ki = 0.3 nM Bioactivity Info	TI LI LO TS
CP0477586 Compound Info	(S)-3-(((S)-6-(3,5-difluorophenyl)-3,3-dimethyl-2-oxopiperidin-1-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one Show/Hide	C32H28F2N4O2	1
1	Ki = 0.3 nM Bioactivity Info	TI LI LO TS
CP0461000 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methylsulfonylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C27H32F2N6O5S	1
1	Ki = 0.5 nM Bioactivity Info	TI LI LO TS
CP0485264 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-morpholin-4-ylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C30H37F2N7O4	1
1	Ki = 0.5 nM Bioactivity Info	TI LI LO TS
CP0420166 Compound Info	(2R)-5-[3-[(8R)-8-(3,5-difluorophenyl)-6,8-dimethyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]propyl]spiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-2'-one Show/Hide	C34H36F2N4O2	1
1	Ki = 0.5 nM Bioactivity Info	TI LI LO TS
CP0401577 Compound Info	(S)-N-(3,5-difluorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H28F2N4O4	1
1	Ki = 0.55 nM Bioactivity Info	TI LI LO TS
CP0487729 Compound Info	(S)-N-(3,5-difluorobenzyl)-N-((2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-3-yl)methyl)pivalamide Show/Hide	C31H28F2N4O2	1
1	Ki = 0.69 nM Bioactivity Info	TI LI LO TS
CP0485262 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methylsulfanylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C27H32F2N6O3S	1
1	Ki = 0.7 nM Bioactivity Info	TI LI LO TS
CP0447664 Compound Info	2,2-dimethyl-N-[2-[[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]-N-[(1R)-1-phenylethyl]propanamide Show/Hide	C27H32N4O4	1
1	Ki = 0.83 nM Bioactivity Info	TI LI LO TS
CP0426974 Compound Info	N-[(3R,6S)-1-(2,2-difluoroethyl)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C26H28F4N6O3	1
1	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
CP0461001 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(pyridin-2-ylmethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C30H31F2N7O3	1
1	Ki = 0.9 nM Bioactivity Info	TI LI LO TS
CP0428911 Compound Info	(S)-N-(3-chloro-5-fluorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H28ClFN4O4	1
1	Ki = 1.2 nM Bioactivity Info	TI LI LO TS
CP0499872 Compound Info	(S)-N-benzyl-N-((2'-oxo-1',2',6,8-tetrahydrospiro[cyclopenta[g]quinoline-7,3'-pyrrolo[2,3-b]pyridine]-3-yl)methyl)pivalamide Show/Hide	C31H30N4O2	1
1	Ki = 1.3 nM Bioactivity Info	TI LI LO TS
CP0439439 Compound Info	N-[(3R,6S)-1-(cyclopropylmethyl)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C28H32F2N6O3	1
1	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0439442 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-fluoroethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C26H29F3N6O3	1
1	Ki = 1.4 nM Bioactivity Info	TI LI LO TS
CP0430585 Compound Info	1-[1-[2-[5-[3-chloro-5-(2,3-dimethylimidazol-4-yl)phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C26H25ClN8O3	2
1	Ki = 1.585 nM Bioactivity Info	TI LI LO TS
2	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0428910 Compound Info	(+/-)-N-(3-fluorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H29FN4O4	1
1	Ki = 1.6 nM Bioactivity Info	TI LI LO TS
CP0426972 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-methylsulfinylethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C27H32F2N6O4S	1
1	Ki = 1.7 nM Bioactivity Info	TI LI LO TS
CP0447680 Compound Info	(+/-)-N-(3-chlorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H29ClN4O4	1
1	Ki = 1.8 nM Bioactivity Info	TI LI LO TS
CP0327608 Compound Info	(S)-N-benzyl-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H30N4O4	1
1	Ki = 1.9 nM Bioactivity Info	TI LI LO TS
CP0463964 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-ethyl-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C26H30F2N6O3	1
1	Ki = 2.4 nM Bioactivity Info	TI LI LO TS
CP0387146 Compound Info	1-[1-[2-[5-[3-chloro-5-(6-methylpyridin-3-yl)phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C27H24ClN7O3	2
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
2	Ki = 125.89 nM Bioactivity Info	TI LI LO TS
CP0524012 Compound Info	1-[1-[2-[5-(3-chloro-5-phenylphenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C27H23ClN6O3	1
1	Ki = 2.512 nM Bioactivity Info	TI LI LO TS
CP0424316 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-methyl-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C25H28F2N6O3	1
1	Ki = 2.7 nM Bioactivity Info	TI LI LO TS
CP0404290 Compound Info	1-[1-[2-[5-[3-chloro-5-(1-ethylpiperidin-4-yl)phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C28H32ClN7O3	2
1	Ki = 3.162 nM Bioactivity Info	TI LI LO TS
2	Ki = 15.85 nM Bioactivity Info	TI LI LO TS
CP0461002 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C24H26F2N6O3	1
1	Ki = 3.6 nM Bioactivity Info	TI LI LO TS
CP0493685 Compound Info	2-(2-oxo-3-pyridin-2-ylbenzimidazol-1-yl)-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl)acetamide Show/Hide	C29H22N6O3	1
1	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0397184 Compound Info	(+/-)-N-(4-fluorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H29FN4O4	1
1	Ki = 3.7 nM Bioactivity Info	TI LI LO TS
CP0383361 Compound Info	1-[1-[2-[5-[3-chloro-5-(1-methylpiperidin-4-yl)phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C27H30ClN7O3	2
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
2	Ki = 19.95 nM Bioactivity Info	TI LI LO TS
CP0404291 Compound Info	1-[1-[2-[5-[3-chloro-5-[1-(2,2-difluoroethyl)piperidin-4-yl]phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C28H30ClF2N7O3	2
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
2	Ki = 79.43 nM Bioactivity Info	TI LI LO TS
CP0494058 Compound Info	1-[1-[2-[5-[3-chloro-5-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C22H18ClF3N6O3	1
1	Ki = 3.981 nM Bioactivity Info	TI LI LO TS
CP0435193 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-(2-hydroxyethyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C26H30F2N6O4	1
1	Ki = 4.2 nM Bioactivity Info	TI LI LO TS
CP0415042 Compound Info	(S)-N-(3,5-dichlorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H28Cl2N4O4	1
1	Ki = 4.4 nM Bioactivity Info	TI LI LO TS
CP0454991 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-1-[2-(dimethylamino)ethyl]-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C28H35F2N7O3	1
1	Ki = 4.9 nM Bioactivity Info	TI LI LO TS
CP0404289 Compound Info	1-[1-[2-[5-[3-chloro-5-(4-methylpiperazin-1-yl)phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C26H29ClN8O3	2
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
2	Ki = 25.12 nM Bioactivity Info	TI LI LO TS
CP0479803 Compound Info	1-[1-[2-[5-[3-chloro-5-[2-(dimethylamino)ethoxy]phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C25H28ClN7O4	2
1	Ki = 5.012 nM Bioactivity Info	TI LI LO TS
2	Ki = 50.12 nM Bioactivity Info	TI LI LO TS
CP0387147 Compound Info	1-[1-[2-[5-(3-chloro-5-morpholin-4-ylphenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C25H26ClN7O4	2
1	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
2	Ki = 125.89 nM Bioactivity Info	TI LI LO TS
CP0526795 Compound Info	1-[1-[2-[5-(3-methyl-5-morpholin-4-ylphenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C26H29N7O4	1
1	Ki = 6.31 nM Bioactivity Info	TI LI LO TS
CP0521189 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-(1,2-thiazol-4-yl)benzimidazol-1-yl]acetamide Show/Hide	C24H20N6O4S	1
1	Ki = 6.8 nM Bioactivity Info	TI LI LO TS
CP0469942 Compound Info	(+/-)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-N-(3-methylbenzyl)pivalamide Show/Hide	C27H32N4O4	1
1	Ki = 7.9 nM Bioactivity Info	TI LI LO TS
CP0520587 Compound Info	1-[1-[2-[5-(3-chloro-5-methoxyphenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C22H21ClN6O4	1
1	Ki = 7.943 nM Bioactivity Info	TI LI LO TS
CP0442300 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-(1,3-thiazol-2-yl)benzimidazol-1-yl]acetamide Show/Hide	C24H20N6O4S	1
1	Ki = 8.7 nM Bioactivity Info	TI LI LO TS
CP0445970 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-3-pyrimidin-5-ylbenzimidazol-1-yl)acetamide Show/Hide	C25H21N7O4	1
1	Ki = 9.5 nM Bioactivity Info	TI LI LO TS
CP0442422 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-[2-oxo-3-[4-(trifluoromethyl)pyrimidin-2-yl]benzimidazol-1-yl]acetamide Show/Hide	C26H20F3N7O4	1
1	Ki = 10 nM Bioactivity Info	TI LI LO TS
CP0471394 Compound Info	N-[(3R,6S)-1-(cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C28H34N6O3	1
1	Ki = 11 nM Bioactivity Info	TI LI LO TS
CP0442298 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-3-pyrazin-2-ylbenzimidazol-1-yl)acetamide Show/Hide	C25H21N7O4	1
1	Ki = 12 nM Bioactivity Info	TI LI LO TS
CP0404252 Compound Info	3-[1-[2-[5-[3-chloro-5-[2-(dimethylamino)ethoxy]phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-4,5-dihydro-1H-1,3-benzodiazepin-2-one Show/Hide	C28H33ClN6O4	2
1	Ki = 12.59 nM Bioactivity Info	TI LI LO TS
2	Ki = 15.85 nM Bioactivity Info	TI LI LO TS
CP0485203 Compound Info	1-[1-[2-[5-(3-bromo-5-chlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18BrClN6O3	1
1	Ki = 12.59 nM Bioactivity Info	TI LI LO TS
CP0447679 Compound Info	(+/-)-N-(2-fluorobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H29FN4O4	1
1	Ki = 14 nM Bioactivity Info	TI LI LO TS
CP0382911 Compound Info	2-[3-(6-methoxypyridin-2-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]acetamide Show/Hide	C27H24N6O5	1
1	Ki = 15 nM Bioactivity Info	TI LI LO TS
CP0404285 Compound Info	1-[1-[2-[5-(3,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18Cl2N6O3	1
1	Ki = 15.85 nM Bioactivity Info	TI LI LO TS
CP0442424 Compound Info	2-[3-(1,1-dioxo-1-thiolan-3-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]acetamide Show/Hide	C25H25N5O6S	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0504391 Compound Info	(R)-3'-methyl-2-((2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2',5'-dione Show/Hide	C28H22N6O3	1
1	Ki = 17 nM Bioactivity Info	TI LI LO TS
CP0484250 Compound Info	N-[(3R,6S)-6-(2-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C24H27FN6O3	1
1	Ki = 22 nM Bioactivity Info	TI LI LO TS
CP0430164 Compound Info	(+/-)-N-(3-cyanobenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C27H29N5O4	1
1	Ki = 23 nM Bioactivity Info	TI LI LO TS
CP0503898 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-3-pyrimidin-2-ylbenzimidazol-1-yl)acetamide Show/Hide	C25H21N7O4	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0388412 Compound Info	(+/-)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-N-(4-(trifluoromethyl)benzyl)pivalamide Show/Hide	C27H29F3N4O4	1
1	Ki = 25 nM Bioactivity Info	TI LI LO TS
CP0391192 Compound Info	1-[1-[2-[5-(3,5-dimethylphenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C23H24N6O3	1
1	Ki = 25.12 nM Bioactivity Info	TI LI LO TS
CP0391218 Compound Info	1-[1-[2-[5-(3-chloro-5-fluorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18ClFN6O3	1
1	Ki = 25.12 nM Bioactivity Info	TI LI LO TS
CP0404287 Compound Info	1-[1-[2-[5-[3,5-bis(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C23H18F6N6O3	1
1	Ki = 25.12 nM Bioactivity Info	TI LI LO TS
CP0521190 Compound Info	2-[3-(3,5-difluorophenyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]-N-[(4R)-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl]acetamide Show/Hide	C27H21F2N5O4	1
1	Ki = 29 nM Bioactivity Info	TI LI LO TS
CP0401917 Compound Info	(R)-3-(3-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)propanamide Show/Hide	C24H24N6O5	1
1	Ki = 31 nM Bioactivity Info	TI LI LO TS
CP0493683 Compound Info	(R)-N-(5-oxo-2-phenyl-1,1',3',5-tetrahydrospiro[imidazole-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C31H24N6O3	1
1	Ki = 34 nM Bioactivity Info	TI LI LO TS
CP0439440 Compound Info	N-[(3R)-6-(2-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C24H27FN6O3	1
1	Ki = 37 nM Bioactivity Info	TI LI LO TS
CP0415041 Compound Info	(+/-)-N-(3-methoxybenzyl)-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C27H32N4O5	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0532115 Compound Info	N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide Show/Hide	C21H18N4O5	1
1	Ki = 48 nM Bioactivity Info	TI LI LO TS
CP0526794 Compound Info	1-[1-[2-[5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C23H24N6O5	1
1	Ki = 50.12 nM Bioactivity Info	TI LI LO TS
CP0471397 Compound Info	N-[(3R,6S)-6-(3-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C24H27FN6O3	1
1	Ki = 51 nM Bioactivity Info	TI LI LO TS
CP0430649 Compound Info	(R)-N-(4'-fluoro-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C26H21FN6O4	1
1	Ki = 55 nM Bioactivity Info	TI LI LO TS
CP0388352 Compound Info	2,2-dimethyl-N-[2-[[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]-N-[(1S)-1-phenylethyl]propanamide Show/Hide	C27H32N4O4	1
1	Ki = 56 nM Bioactivity Info	TI LI LO TS
CP0443570 Compound Info	1-(1-((3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-ylcarbamoyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridine 4-oxide Show/Hide	C26H27F5N6O4	1
1	Ki = 66 nM Bioactivity Info	TI LI LO TS
CP0442414 Compound Info	N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(3-methyl-2-oxobenzimidazol-1-yl)acetamide Show/Hide	C21H19N5O4	1
1	Ki = 78 nM Bioactivity Info	TI LI LO TS
CP0439441 Compound Info	4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R,6S)-2-oxo-6-phenylazepan-3-yl]piperidine-1-carboxamide Show/Hide	C24H28N6O3	1
1	Ki = 83 nM Bioactivity Info	TI LI LO TS
CP0442412 Compound Info	N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(2-oxo-3-phenylbenzimidazol-1-yl)acetamide Show/Hide	C26H21N5O4	1
1	Ki = 87 nM Bioactivity Info	TI LI LO TS
CP0485263 Compound Info	N-[(3R)-6-(3-fluorophenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C24H27FN6O3	1
1	Ki = 93 nM Bioactivity Info	TI LI LO TS
CP0505618 Compound Info	N-(2',5'-dioxospiro[1,3-dihydroindene-2,3'-pyrrolidine]-5-yl)-2-(2-oxo-3-pyridin-2-ylbenzimidazol-1-yl)acetamide Show/Hide	C26H21N5O4	1
1	Ki = 96 nM Bioactivity Info	TI LI LO TS
CP0381134 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-1H-pyridin-3-yl)piperidine-1-carboxamide Show/Hide	C25H27F5N4O3	1
1	Ki = 100 nM Bioactivity Info	TI LI LO TS
CP0377035 Compound Info	N-(1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl)-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide Show/Hide	C21H18N4O5	1
1	Ki = 103 nM Bioactivity Info	TI LI LO TS
CP0383360 Compound Info	1-[1-[2-[5-(2,5-dichlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18Cl2N6O3	1
1	Ki = 125.89 nM Bioactivity Info	TI LI LO TS
CP0404286 Compound Info	1-[1-[2-[5-(3,5-difluorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18F2N6O3	1
1	Ki = 125.89 nM Bioactivity Info	TI LI LO TS
CP0372067 Compound Info	(R)-N-(5-oxo-2-(pyridin-3-yl)-1,1',3',5-tetrahydrospiro[imidazole-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C30H23N7O3	1
1	Ki = 130 nM Bioactivity Info	TI LI LO TS
CP0405462 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxamide Show/Hide	C23H27F5N4O3	1
1	Ki = 140 nM Bioactivity Info	TI LI LO TS
CP0524011 Compound Info	1-[1-[2-[5-(2,3-dichlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18Cl2N6O3	1
1	Ki = 158.49 nM Bioactivity Info	TI LI LO TS
CP0494662 Compound Info	3'-methyl-2-((2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoxaline-7,4'-imidazolidine]-2',5'-dione Show/Hide	C27H21N7O3	1
1	Ki = 185 nM Bioactivity Info	TI LI LO TS
CP0404288 Compound Info	1-[1-[2-[5-(3-morpholin-4-yl-5-phenylphenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C31H31N7O4	1
1	Ki = 199.53 nM Bioactivity Info	TI LI LO TS
CP0469858 Compound Info	1-[1-[2-(5-phenyl-1,3,4-oxadiazol-2-yl)acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H20N6O3	1
1	Ki = 199.53 nM Bioactivity Info	TI LI LO TS
CP0541932 Compound Info	(R)-N-(2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C25H20N6O4	1
1	Ki = 230 nM Bioactivity Info	TI LI LO TS
CP0473876 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(6-oxo-3-phenyl-1H-pyridazin-5-yl)piperidine-1-carboxamide Show/Hide	C30H30F5N5O3	1
1	Ki = 240 nM Bioactivity Info	TI LI LO TS
CP0404284 Compound Info	1-[1-[2-[5-(3,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18Cl2N6O3	1
1	Ki = 251.19 nM Bioactivity Info	TI LI LO TS
CP0493682 Compound Info	2-(2-oxo-3-pyridin-2-ylbenzimidazol-1-yl)-N-(2'-oxospiro[1,3-dihydroindene-2,3'-pyrrolidine]-5-yl)acetamide Show/Hide	C26H23N5O3	1
1	Ki = 270 nM Bioactivity Info	TI LI LO TS
CP0456866 Compound Info	N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(2-oxo-3H-benzimidazol-1-yl)acetamide Show/Hide	C20H17N5O4	1
1	Ki = 280 nM Bioactivity Info	TI LI LO TS
CP0442279 Compound Info	N-(2',5'-dioxospiro[1,3-dihydroindene-2,4'-imidazolidine]-5-yl)-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide Show/Hide	C20H16N4O5	1
1	Ki = 309 nM Bioactivity Info	TI LI LO TS
CP0479677 Compound Info	1-[1-[2-[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H19ClN6O3	1
1	Ki = 316.23 nM Bioactivity Info	TI LI LO TS
CP0405463 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-1,3-dioxo-2,9-diazaspiro[5.5]undecane-9-carboxamide Show/Hide	C24H27F5N4O4	1
1	Ki = 340 nM Bioactivity Info	TI LI LO TS
CP0500599 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2,4-dioxo-3,9-diazaspiro[5.5]undecane-9-carboxamide Show/Hide	C24H27F5N4O4	1
1	Ki = 390 nM Bioactivity Info	TI LI LO TS
CP0426942 Compound Info	4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-(3-thienyl)azepan-3-yl]piperidine-1-carboxamide Show/Hide	C22H26N6O3S	1
1	Ki = 470 nM Bioactivity Info	TI LI LO TS
CP0427920 Compound Info	4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-propan-2-ylazepan-3-yl]piperidine-1-carboxamide Show/Hide	C21H30N6O3	1
1	Ki = 470 nM Bioactivity Info	TI LI LO TS
CP0501396 Compound Info	1-[1-[2-[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H19ClN6O3	1
1	Ki = 501.19 nM Bioactivity Info	TI LI LO TS
CP0405461 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-1-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decane-8-carboxamide Show/Hide	C23H26F5N5O4	1
1	Ki = 510 nM Bioactivity Info	TI LI LO TS
CP0493684 Compound Info	2-(2-oxo-3-pyridin-2-ylbenzimidazol-1-yl)-N-(2'-oxospiro[1,3-dihydroindene-2,3'-1H-indole]-5-yl)acetamide Show/Hide	C30H23N5O3	1
1	Ki = 520 nM Bioactivity Info	TI LI LO TS
CP0668570 Compound Info	(R)-4-(2,4-dioxoimidazolidin-1-yl)-N-(2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)piperidine-1-carboxamide Show/Hide	C26H25F3N6O4	1
1	Ki = 520 nM Bioactivity Info	TI LI LO TS
CP0514337 Compound Info	N-(2',5'-dioxospiro[7,8-dihydro-5H-naphthalene-6,4'-imidazolidine]-2-yl)-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide Show/Hide	C21H18N4O5	1
1	Ki = 607 nM Bioactivity Info	TI LI LO TS
CP0485261 Compound Info	N-[(3R)-6-benzyl-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C25H30N6O3	1
1	Ki = 610 nM Bioactivity Info	TI LI LO TS
CP0496107 Compound Info	(S)-N-(5'-fluoro-3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-6'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C26H21FN6O4	1
1	Ki = 720 nM Bioactivity Info	TI LI LO TS
CP0463963 Compound Info	N-[(3R)-6-(4-hydroxyphenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C24H28N6O4	1
1	Ki = 770 nM Bioactivity Info	TI LI LO TS
CP0479800 Compound Info	1-[1-[2-[5-(2,6-dichlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H18Cl2N6O3	1
1	Ki = 794.33 nM Bioactivity Info	TI LI LO TS
CP0494272 Compound Info	(R)-N-benzyl-N-(2-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imidazolidine-4,2'-indene]-5'-ylamino)-2-oxoethyl)pivalamide Show/Hide	C26H30N4O4	1
1	Ki = 800 nM Bioactivity Info	TI LI LO TS
CP0501397 Compound Info	1-[1-[2-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C21H19ClN6O3	1
1	Ki = 1000 nM Bioactivity Info	TI LI LO TS
CP0532114 Compound Info	N-[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]-2-(2-oxo-1,3-benzoxazol-3-yl)acetamide Show/Hide	C21H18N4O5	1
1	Ki = 1050 nM Bioactivity Info	TI LI LO TS
CP0505604 Compound Info	N-[(3R)-6-(4-methylphenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C25H30N6O3	1
1	Ki = 1100 nM Bioactivity Info	TI LI LO TS
CP0541579 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2-oxospiro[1,4-dihydroquinoline-3,4'-piperidine]-1'-carboxamide Show/Hide	C28H29F5N4O3	1
1	Ki = 1249 nM Bioactivity Info	TI LI LO TS
CP0501828 Compound Info	N-[(3R)-6-(2-methoxyphenyl)-2-oxoazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide Show/Hide	C25H30N6O4	1
1	Ki = 1700 nM Bioactivity Info	TI LI LO TS
CP0013441 Compound Info	(R)-4-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)-N-(2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)piperidine-1-carboxamide Show/Hide	C30H27F3N6O3	1
1	Ki = 2200 nM Bioactivity Info	TI LI LO TS
CP0510664 Compound Info	1-[1-[2-(2-methoxy-5-phenylphenyl)acetyl]piperidin-4-yl]-3H-imidazo[4,5-b]pyridin-2-one Show/Hide	C26H26N4O3	1
1	Ki = 2511.89 nM Bioactivity Info	TI LI LO TS
CP0541933 Compound Info	(R)-N-(2-cyclopropyl-5-oxo-1,1',3',5-tetrahydrospiro[imidazole-4,2'-indene]-5'-yl)-2-(2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)acetamide Show/Hide	C28H24N6O3	1
1	Ki = 2600 nM Bioactivity Info	TI LI LO TS
CP0401156 Compound Info	2-(2-oxo-3-pyridin-2-ylbenzimidazol-1-yl)-N-(2'-oxospiro[1,3-dihydroindene-2,3'-piperidine]-5-yl)acetamide Show/Hide	C27H25N5O3	1
1	Ki = 2700 nM Bioactivity Info	TI LI LO TS
CP0505605 Compound Info	4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-pyridin-2-ylazepan-3-yl]piperidine-1-carboxamide Show/Hide	C23H27N7O3	1
1	Ki = 4400 nM Bioactivity Info	TI LI LO TS
CP0538626 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-hydroxypiperidine-1-carboxamide Show/Hide	C20H24F5N3O3	1
1	Ki = 5000 nM Bioactivity Info	TI LI LO TS
CP0533063 Compound Info	(S)-3-methyl-2'-((2-oxo-3-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl)-5',7'-dihydrospiro[imidazolidine-4,6'-indeno[5,6-d]oxazole]-2,5-dione Show/Hide	C26H20N6O4	1
1	Ki = 6000 nM Bioactivity Info	TI LI LO TS
CP0455284 Compound Info	N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-2,4-dioxo-1-oxa-3,8-diazaspiro[4.5]decane-8-carboxamide Show/Hide	C22H23F5N4O5	1
1	Ki = 8900 nM Bioactivity Info	TI LI LO TS
CP0528591 Compound Info	4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)-N-[(3R)-2-oxo-6-pyridin-3-ylazepan-3-yl]piperidine-1-carboxamide Show/Hide	C23H27N7O3	1
1	Ki = 9900 nM Bioactivity Info	TI LI LO TS

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About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han