Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4'S)-3'-methyl-2-((2a-methyl-4-oxo-2a,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolin-1(2H)-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2',5'-dione
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 PubChem ID
CID: 46885243
Canonical SMILES
CN1C(=O)NC(=O)[C@@]11Cc2cc3ccc(CN4CC5(C)CC(=O)Nc6cccc4c56)nc3cc2C1
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Compound Formula C27H25N5O3
Compound Structure
Protein Name
 Protein Info 
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Calcitonin-like receptor
>
Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 2.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 6.5 nM
   TI
   LI
   LO
   TS
3
Ki = 0.52 nM
   TI
   LI
   LO
   TS