Brief Information of the Compound and Protein
Compound Name
2-[2-oxo-3-(oxolan-3-yl)benzimidazol-1-yl]-N-[(2S)-2'-oxospiro[1,3-dihydroindene-2,3'-1H-pyrrolo[2,3-b]pyridine]-5-yl]acetamide
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PubChem ID
CID: 44570580
Canonical SMILES
O=C(Cn1c2ccccc2n(C2CCOC2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31
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Compound Formula C28H25N5O4
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Calcitonin-like receptor
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Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 5.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 27 nM
   TI
   LI
   LO
   TS
3
Ki = 1.2 nM
   TI
   LI
   LO
   TS