General Information of the Compound
Compound ID
CP0493682
Compound Name
2-(2-oxo-3-pyridin-2-ylbenzimidazol-1-yl)-N-(2'-oxospiro[1,3-dihydroindene-2,3'-pyrrolidine]-5-yl)acetamide
    Show/Hide
Structure
Formula
C26H23N5O3
Molecular Weight
453.502
Canonical SMILES
O=C(Cn1c2ccccc2n(-c2ccccn2)c1=O)Nc1ccc2CC3(CCNC3=O)Cc2c1
    Show/Hide
InChI
InChI=1S/C26H23N5O3/c32-23(29-19-9-8-17-14-26(15-18(17)13-19)10-12-28-24(26)33)16-30-20-5-1-2-6-21(20)31(25(30)34)22-7-3-4-11-27-22/h1-9,11,13H,10,12,14-16H2,(H,28,33)(H,29,32)
    Show/Hide
InChIKey
NBAQFYQQNMLQDY-UHFFFAOYSA-N
Physicochemical Property
logP
2.4308
Rotatable Bonds
4
Heavy Atom Count
34
Polar Areas
98.02
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 11576078
SID: 16678428
ChEMBL ID
CHEMBL465280
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01670, Calcitonin gene-related peptide type 1 receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 270 nM
   TI
   LI
   LO
   TS