Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-(2,5-dioxo-2,4,5,6-tetrahydro-1H-imidazo[1,5,4-de]quinoxalin-1-yl)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)acetamide
    Show/Hide
 PubChem ID
CID: 25181509
SID: 57289098
Canonical SMILES
O=C(Cn1c2cccc3NC(=O)Cn(c23)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31
    Show/Hide
Compound Formula C26H20N6O4
Compound Structure
Protein Name
 Protein Info 
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Calcitonin-like receptor
>
Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 0.28 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.62 nM
   TI
   LI
   LO
   TS
3
Ki = 0.039 nM
   TI
   LI
   LO
   TS
4
Ki = 0.04 nM
   TI
   LI
   LO
   TS