Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-N-(2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridine]-5-yl)-2-(2-oxo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-1-yl)acetamide
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 PubChem ID
CID: 44570615
Canonical SMILES
O=C(CN1C(=O)C2(CCOCC2)c2ccccc12)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31
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Compound Formula C29H26N4O4
Compound Structure
Protein Name
 Protein Info 
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Calcitonin-like receptor
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Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 5.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 39 nM
   TI
   LI
   LO
   TS
3
Ki = 1.7 nM
   TI
   LI
   LO
   TS