Brief Information of the Compound and Protein
Compound Name
N-[(3R,6S)-1-(cyclopropylmethyl)-2-oxo-6-phenylazepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
    Show/Hide
PubChem ID
CID: 11168000
SID: 16247548
Canonical SMILES
O=C(N[C@@H]1CC[C@H](CN(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)n1c2cccnc2[nH]c1=O
    Show/Hide
Compound Formula C28H34N6O3
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Calcitonin-like receptor
>
Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 11 nM
   TI
   LI
   LO
   TS
CL000748 NAL1A clone C4E10 Mus musculus (Mouse)  2
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
2
IC50 = 340 nM
   TI
   LI
   LO
   TS