Brief Information of the Compound and Protein
Compound Name
N-[(1R)-1-(3,5-difluorophenyl)ethyl]-2,2-dimethyl-N-[[(3S)-2-oxospiro[1H-pyrrolo[2,3-b]pyridine-3,7'-6,8-dihydrocyclopenta[g]quinoline]-3'-yl]methyl]propanamide
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PubChem ID
CID: 52942173
Canonical SMILES
C[C@@H](N(Cc1cnc2cc3C[C@]4(Cc3cc2c1)C(=O)Nc1ncccc41)C(=O)C(C)(C)C)c1cc(F)cc(F)c1
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Compound Formula C32H30F2N4O2
Compound Structure
Protein Name
Calcitonin gene-related peptide type 1 receptor
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Calcitonin-like receptor
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Calcitonin gene-related peptide receptor
Uniprot ID
Q16602
Gene Name
CALCRL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 0.12 nM
   TI
   LI
   LO
   TS