| Compound ID |
Compound Name |
Compound Formula |
|
CP0479968
|
1-[4-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]phenyl]piperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C27H34N8O
|
1
|
| 1 |
GI50 = 25.1 nM
|
|
|
|
CP0441015
|
N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]propanamide
Show/Hide
|
C30H31F3N6OS
|
1
|
| 1 |
GI50 = 42 nM
|
|
|
|
CP0667764
|
N-(2,6-difluoro-3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H24F2N6O3
|
2
|
| 1 |
IC50 = 0.6026 nM
|
|
|
| 2 |
IC50 = 7244.36 nM
|
|
|
|
CP0664771
|
N-(2,6-difluoro-3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H23F2N7O3
|
2
|
| 1 |
IC50 = 0.631 nM
|
|
|
| 2 |
IC50 = 4677.35 nM
|
|
|
|
CP0786852
|
2-((2,6-difluoro-3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H21F2N5O3
|
2
|
| 1 |
IC50 = 2.344 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667757
|
N-(2,6-dichloro-3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H24Cl2N6O3
|
2
|
| 1 |
IC50 = 2.63 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664765
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)isonicotinamide
Show/Hide
|
C29H25N7O3
|
2
|
| 1 |
IC50 = 2.818 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701298
|
N-(3,5-Dimethoxyphenyl)-N-[3-(4-methoxypyrimidin-2-yl)prop-2-yn-1-yl]-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O3
|
2
|
| 1 |
IC50 = 2.884 nM
|
|
|
| 2 |
IC50 = 6309.57 nM
|
|
|
|
CP0661487
|
3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea monophosphate
Show/Hide
|
C26H34Cl2N7O7P
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0701306
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-ethoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O3
|
2
|
| 1 |
IC50 = 3.631 nM
|
|
|
| 2 |
IC50 = 7585.78 nM
|
|
|
|
CP0795293
|
(2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyridin-4-yl)methanol
Show/Hide
|
C29H26N6O3
|
2
|
| 1 |
IC50 = 4.467 nM
|
|
|
| 2 |
IC50 = 7762.47 nM
|
|
|
|
CP0707093
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
2
|
| 1 |
IC50 = 4.786 nM
|
|
|
| 2 |
IC50 = 4365.16 nM
|
|
|
|
CP0698828
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5R)-2,5-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 4.898 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700917
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-isopropoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H29N7O3
|
2
|
| 1 |
IC50 = 6.026 nM
|
|
|
| 2 |
IC50 = 4570.88 nM
|
|
|
|
CP0692220
|
N1-(2-chloro-3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C25H30Cl2N6O2
|
2
|
| 1 |
IC50 = 6.457 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664751
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)isonicotinonitrile
Show/Hide
|
C29H23N7O2
|
2
|
| 1 |
IC50 = 6.761 nM
|
|
|
| 2 |
IC50 = 7762.47 nM
|
|
|
|
CP0749417
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 6.761 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673353
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C29H37N7O2
|
2
|
| 1 |
IC50 = 7.079 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0770858
|
(S)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(2-methylpyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 7.586 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744805
|
N-(2,6-dichloro-3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H23Cl2N7O3
|
1
|
| 1 |
IC50 = 7.762 nM
|
|
|
|
CP0808360
|
N-(3-(5,6-dihydropyridin-1(2H)-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H33ClN6O2
|
2
|
| 1 |
IC50 = 9.333 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657948
|
N-(3,5-Dimethoxyphenyl)-N'-(1-methylethyl)-N-{3-[1-(tetrahydro-2H-pyran-4-ylmethyl)-1 H-pyrazol-4-yl]quinoxalin-6-yl}ethane-1,2-diamine hydrochloride
Show/Hide
|
C30H39ClN6O3
|
2
|
| 1 |
IC50 = 9.55 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672788
|
(S)-N-((1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)methyl)-1,1,1-trifluoromethanesulfonamide
Show/Hide
|
C29H34F3N7O4S
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692287
|
3-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propanenitrile
Show/Hide
|
C27H31N7O2
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702407
|
N-(2,6-Difluoro-3,5-dimethoxyphenyl)-N'-(1-methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C25H28F2N6O2
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 6025.6 nM
|
|
|
|
CP0719271
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C29H36N6O3
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0737875
|
N1-(2,6-difluoro-3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H25F5N6O2
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0388620
|
methyl N-[4-[7-amino-3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxypyrazolo[1,5-a]pyrimidin-6-yl]phenyl]carbamate
Show/Hide
|
C28H32N6O5
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0786849
|
(S)-2-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)acetonitrile hydrochloride
Show/Hide
|
C29H34ClN7O2
|
2
|
| 1 |
IC50 = 10.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702439
|
N-(3-(4-aminopyridin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O2
|
2
|
| 1 |
IC50 = 10.47 nM
|
|
|
| 2 |
IC50 = 870.96 nM
|
|
|
|
CP0683288
|
N-(3,5-dimethoxyphenyl)-3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O4S
|
2
|
| 1 |
IC50 = 10.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726411
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O2
|
2
|
| 1 |
IC50 = 10.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735248
|
N-(3,5-Dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-[3-(4-methylpyridin-2-yl)prop-2-yn-1-yl]quinoxalin-6-amine
Show/Hide
|
C29H26N6O2
|
2
|
| 1 |
IC50 = 10.96 nM
|
|
|
| 2 |
IC50 = 5888.44 nM
|
|
|
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CP0751775
|
2-(4-(7-((3,5-dimethoxyphenyl)(3-(pyrrolidin-1-yl)propyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol hydrochloride
Show/Hide
|
C28H35ClN6O3
|
2
|
| 1 |
IC50 = 11.75 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
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CP0707084
|
(1s,4s)-N1-(3,5-dimethoxyphenyl)-N4-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)cyclohexane-1,4-diamine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 13.18 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
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CP0701289
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5S)-2,5-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 13.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704132
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)propane-2-sulfonamide
Show/Hide
|
C25H30N6O4S
|
2
|
| 1 |
IC50 = 14.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657945
|
N-(2,6-difluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C23H19F2N5O2
|
2
|
| 1 |
IC50 = 15.14 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664775
|
N-(3,5-dimethoxyphenyl)-N-(3-(2,2-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 15.14 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692223
|
N1-(3,5-dimethoxy-2-methylphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 15.49 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698840
|
N-{3,5-Bis[(2H3)methyloxy]phenyl}-N'-(1-methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl](2H4)ethane-1,2-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 15.49 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672830
|
N1-(3,5-dimethoxyphenyl)-N3-(1-fluoro-2-methylpropan-2-yl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C27H33FN6O2
|
2
|
| 1 |
IC50 = 15.85 nM
|
|
|
| 2 |
IC50 = 7585.78 nM
|
|
|
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CP0831842
|
N-{3,5-Bis[(2H3)methyloxy]phenyl}-3-[1-(1-methylethyl)-1H-pyrazol-4-yl]-N-(3-pyridin-4-ylprop-2-yn-1-yl)quinoxalin-6-amine
Show/Hide
|
C30H28N6O2
|
2
|
| 1 |
IC50 = 15.85 nM
|
|
|
| 2 |
IC50 = 6025.6 nM
|
|
|
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CP0673335
|
N-(3,5-Dimethoxyphenyl)-N-[3-(1-ethyl-1H-pyrazol-4-yl)quinoxalin-6-yl]-N'-(1-methylethyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 16.22 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0701275
|
N-(2-chloro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H32Cl2N6O2
|
2
|
| 1 |
IC50 = 16.22 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0707088
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-4-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C28H24N6O2
|
2
|
| 1 |
IC50 = 16.22 nM
|
|
|
| 2 |
IC50 = 5623.41 nM
|
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CP0744817
|
1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)azetidin-3-ol
Show/Hide
|
C26H30N6O3
|
2
|
| 1 |
IC50 = 16.6 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0762381
|
N-(3,5-dimethoxy-2-methylphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 16.6 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0657879
|
(R)-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)methanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 17.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
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CP0673348
|
N-(2-(5,6-dihydropyridin-1(2H)-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H31ClN6O2
|
2
|
| 1 |
IC50 = 17.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708035
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5S)-2,5-dimethylpyrrolidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H34N6O2
|
2
|
| 1 |
IC50 = 18.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
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CP0734013
|
7-[N-[2-(dimethylsulfamoylamino)ethyl]-3,5-dimethoxy-anilino]-2-(1-methylpyrazol-4-yl)quinoxaline
Show/Hide
|
C24H29N7O4S
|
2
|
| 1 |
IC50 = 18.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0773263
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)methanesulfonamide
Show/Hide
|
C23H26N6O4S
|
2
|
| 1 |
IC50 = 18.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692233
|
(S)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O2
|
2
|
| 1 |
IC50 = 19.05 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704128
|
N-(3-(2-aminopyrimidin-4-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H24N8O2
|
2
|
| 1 |
IC50 = 19.05 nM
|
|
|
| 2 |
IC50 = 1348.96 nM
|
|
|
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CP0704137
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyrimidin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O2
|
2
|
| 1 |
IC50 = 19.05 nM
|
|
|
| 2 |
IC50 = 6918.31 nM
|
|
|
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CP0704633
|
1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-3-ol hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 19.05 nM
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|
| 2 |
IC50 > 10000 nM
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|
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CP0702106
|
3-((3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(2-(isopropylamino)ethyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C28H35N7O2
|
2
|
| 1 |
IC50 = 19.5 nM
|
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|
| 2 |
IC50 > 10000 nM
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CP0762382
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(R)-3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H26F3N5O3
|
2
|
| 1 |
IC50 = 19.95 nM
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|
| 2 |
IC50 > 10000 nM
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|
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CP0672782
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(2S)-1-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-3-[(1-methylethyl)amino]propan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O3
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2
|
| 1 |
IC50 = 20.89 nM
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| 2 |
IC50 > 10000 nM
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CP0672831
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(thiazol-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C26H22N6O2S
|
2
|
| 1 |
IC50 = 20.89 nM
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|
|
| 2 |
IC50 = 5623.41 nM
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CP0776282
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N1-(2,6-dichloro-3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H28Cl2N6O2
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2
|
| 1 |
IC50 = 20.89 nM
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| 2 |
IC50 = 6760.83 nM
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CP0701301
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N1-isopropyl-N2-(7-methoxybenzo[d][1,3]dioxol-5-yl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H28N6O3
|
2
|
| 1 |
IC50 = 21.38 nM
|
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|
| 2 |
IC50 > 10000 nM
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|
|
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CP0719256
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1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)piperidine-3-carboxamide
Show/Hide
|
C29H35N7O3
|
2
|
| 1 |
IC50 = 21.38 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
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CP0756736
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2-(4-{7-[(3,5-Dimethoxyphenyl){2-[(1-methylethyl)amino]ethyl}amino]quinoxalin-2-yl}-1H-pyrazol-1-yl)-N-methylacetamide hydrochloride
Show/Hide
|
C27H34ClN7O3
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2
|
| 1 |
IC50 = 21.88 nM
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|
|
| 2 |
IC50 > 10000 nM
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|
|
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CP0686859
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N-isopropyl-N'-[3-methoxy-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 23.99 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
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CP0690269
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N-(3-(6-amino-2-methylpyrimidin-4-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H26N8O2
|
2
|
| 1 |
IC50 = 24.55 nM
|
|
|
| 2 |
IC50 = 1412.54 nM
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CP0707087
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N-(3,5-dimethoxyphenyl)-N-((5,5-dimethylmorpholin-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 25.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0756692
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3-(4-(3-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propyl)piperazin-1-yl)propan-1-ol hydrochloride
Show/Hide
|
C34H49ClN8O3
|
2
|
| 1 |
IC50 = 25.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0672889
|
(R)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-yl acetate
Show/Hide
|
C25H24F3N5O4
|
2
|
| 1 |
IC50 = 26.3 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0707083
|
N-(3,5-Dimethoxyphenyl)-N'-(1-methylethyl)-N-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H29ClN6O2
|
2
|
| 1 |
IC50 = 26.92 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0649802
|
N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C26H30N6O2
|
2
|
| 1 |
IC50 = 27.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0692272
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2-(4-(7-((3,5-dimethoxyphenyl)(3-(isopropylamino)propyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C28H35N7O3
|
2
|
| 1 |
IC50 = 27.54 nM
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|
|
| 2 |
IC50 > 10000 nM
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|
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|
CP0692285
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(4-hydroxypyridin-2-yl)acetamide
Show/Hide
|
C27H25N7O4
|
2
|
| 1 |
IC50 = 28.18 nM
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|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0707114
|
N-(3,5-Dimethoxyphenyl)-N-(1H-imidazol-2-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H23N7O2
|
2
|
| 1 |
IC50 = 28.84 nM
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|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0673332
|
N'-(3,5-dimethoxyphenyl)-N-isopropyl-N'-[3-[1-(trideuteriomethyl)pyrazol-4-yl]quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 29.51 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0672789
|
2-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)ethanol
Show/Hide
|
C29H36N6O3
|
2
|
| 1 |
IC50 = 30.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0692234
|
(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)methanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 30.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701286
|
2-(1-(2-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)propan-2-ol
Show/Hide
|
C32H42N6O3
|
2
|
| 1 |
IC50 = 30.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0770859
|
N-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)propyl)-2,2,2-trifluoroacetamide, 2,2,2-trifluoroacetate salt
Show/Hide
|
C26H24F6N6O5
|
2
|
| 1 |
IC50 = 30.2 nM
|
|
|
| 2 |
IC50 = 9332.54 nM
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|
|
|
CP0698926
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-fluoropyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H32ClFN6O2
|
2
|
| 1 |
IC50 = 30.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0686570
|
(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazol-5-yl)methanol
Show/Hide
|
C26H32N6O3
|
2
|
| 1 |
IC50 = 31.62 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0701309
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propylamino)acetamide
Show/Hide
|
C25H29N7O3
|
2
|
| 1 |
IC50 = 31.62 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744802
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N2-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 31.62 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0746821
|
1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidine-3-carboxamide
Show/Hide
|
C28H33N7O3
|
2
|
| 1 |
IC50 = 31.62 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0786940
|
2-(4-(7-((3,5-dimethoxyphenyl)(3-(pyrrolidin-1-yl)propyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C29H35N7O3
|
2
|
| 1 |
IC50 = 31.62 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726550
|
N-(3,5-dimethoxyphenyl)-N-(3-((2S,5R)-2,5-dimethylpyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 32.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0744801
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C28H24N6O2
|
2
|
| 1 |
IC50 = 32.36 nM
|
|
|
| 2 |
IC50 = 9549.93 nM
|
|
|
|
CP0841622
|
(R)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O2
|
2
|
| 1 |
IC50 = 33.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0683289
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(piperidin-1-yl)propan-2-ol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 33.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690288
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(methylamino)pyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O2
|
2
|
| 1 |
IC50 = 33.88 nM
|
|
|
| 2 |
IC50 = 5888.44 nM
|
|
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|
CP0726558
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(pyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H31ClN6O2
|
2
|
| 1 |
IC50 = 33.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704178
|
(R)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(2-methylpyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 34.67 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717323
|
N1-(3,5-dimethoxyphenyl)-N2-methyl-N1-(3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C28H35ClN6O3
|
2
|
| 1 |
IC50 = 34.67 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749419
|
N1-(3,5-dimethoxyphenyl)-N3-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 34.67 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0833205
|
(S)-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)methanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 35.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664758
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1,5-dimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-isopropylethane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 36.31 nM
|
|
|
| 2 |
IC50 = 6165.95 nM
|
|
|
|
CP0720056
|
(S)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 36.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0875201
|
7-[N-[3-(dimethylsulfamoylamino)propyl]-3,5-dimethoxy-anilino]-2-(1-methylpyrazol-4-yl)quinoxaline
Show/Hide
|
C25H31N7O4S
|
2
|
| 1 |
IC50 = 36.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707115
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine hydrochloride
Show/Hide
|
C26H33ClN6O2
|
2
|
| 1 |
IC50 = 37.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0875235
|
N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)methanesulfonamide
Show/Hide
|
C24H28N6O4S
|
2
|
| 1 |
IC50 = 37.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719249
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(methylsulfonyl)pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C28H34N6O4S
|
2
|
| 1 |
IC50 = 38.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0809104
|
(S)-1-(2-((3,5-dimethoxyphenyl)(3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidine-3-carbonitrile
Show/Hide
|
C32H37N7O3
|
2
|
| 1 |
IC50 = 38.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0837822
|
(S)-1-((S)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-hydroxypropyl)pyrrolidine-3-carbonitrile hydrochloride
Show/Hide
|
C28H32ClN7O3
|
2
|
| 1 |
IC50 = 38.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686857
|
N1-(3,5-dimethoxyphenyl)-N2-ethyl-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 38.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726488
|
2-((2-chloro-3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H22ClN5O3
|
2
|
| 1 |
IC50 = 39.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692231
|
N-(3,5-dimethoxyphenyl)-3-(1-isopropyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 40.74 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672791
|
(R)-2-(1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-yl)acetonitrile hydrochloride
Show/Hide
|
C29H34ClN7O2
|
2
|
| 1 |
IC50 = 42.66 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688437
|
N1-(3,5-dimethoxyphenyl)-N2,N2-diethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 42.66 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704723
|
2-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylamino)ethanol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 42.66 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688443
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-morpholinopropyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 43.65 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690296
|
N1-(3,5-dimethoxyphenyl)-N3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 43.65 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698829
|
3-methoxy-N-methyl-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)benzamide
Show/Hide
|
C28H33N7O2
|
2
|
| 1 |
IC50 = 44.67 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700914
|
N1-(3,5-dimethoxyphenyl)-2-fluoro-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C23H25FN6O2
|
2
|
| 1 |
IC50 = 44.67 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704142
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-methylpyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O2
|
2
|
| 1 |
IC50 = 44.67 nM
|
|
|
| 2 |
IC50 = 7585.78 nM
|
|
|
|
CP0751772
|
N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(2-(pyrrolidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C25H29ClN6O2
|
2
|
| 1 |
IC50 = 44.67 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664747
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2,2,2-trifluoroethyl)propanamide
Show/Hide
|
C25H25F3N6O3
|
2
|
| 1 |
IC50 = 45.71 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701266
|
2-(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)phenoxy)ethanol
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 46.77 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701303
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrazin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C27H23N7O2
|
2
|
| 1 |
IC50 = 46.77 nM
|
|
|
| 2 |
IC50 = 3715.35 nM
|
|
|
|
CP0702251
|
N1-(4-aminobenzyl)-N2-(3,5-dimethoxyphenyl)-N1-isopropyl-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C32H37N7O2
|
2
|
| 1 |
IC50 = 46.77 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717320
|
3-((2-(isopropylamino)ethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C26H31N7O2
|
2
|
| 1 |
IC50 = 46.77 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0772374
|
(S)-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-2-yl)methanol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 47.86 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692290
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2-methylpiperidin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 48.98 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726424
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-ethylpyrimidin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O2
|
2
|
| 1 |
IC50 = 48.98 nM
|
|
|
| 2 |
IC50 = 7413.1 nM
|
|
|
|
CP0657884
|
N1-(3,5-dimethoxyphenyl)-N2,N2-dimethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 50.12 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657941
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(isopropylamino)propan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O3
|
2
|
| 1 |
IC50 = 50.12 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686861
|
(2R*)-3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C23H22F3N5O3
|
2
|
| 1 |
IC50 = 50.12 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0803484
|
N2-(3,5-dimethoxyphenyl)-N1-isopropyl-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 50.12 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692267
|
2-((2,6-dichloro-3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H21Cl2N5O3
|
2
|
| 1 |
IC50 = 51.29 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735320
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 51.29 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0809103
|
N1-(3,5-dimethoxyphenyl)-N3-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C26H32N6O2
|
2
|
| 1 |
IC50 = 51.29 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701297
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C30H40ClN7O2
|
2
|
| 1 |
IC50 = 52.48 nM
|
|
|
| 2 |
IC50 = 4265.8 nM
|
|
|
|
CP0704711
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrimidin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C27H23N7O2
|
2
|
| 1 |
IC50 = 52.48 nM
|
|
|
| 2 |
IC50 = 7079.46 nM
|
|
|
|
CP0649806
|
1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-3-ol hydrochloride
Show/Hide
|
C26H31ClN6O3
|
2
|
| 1 |
IC50 = 53.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664746
|
3-((2-(isopropylamino)ethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 53.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672787
|
N1-(3-fluoro-5-methoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H27FN6O
|
2
|
| 1 |
IC50 = 53.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0774606
|
N1-(cyclopropylmethyl)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C26H30N6O2
|
2
|
| 1 |
IC50 = 53.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692262
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(morpholin-3-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H28N6O3
|
2
|
| 1 |
IC50 = 54.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707085
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-((tetrahydrofuran-2-yl)methyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 54.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649789
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 57.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664757
|
3-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 57.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688468
|
3-((3,5-dimethoxyphenyl)(3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanenitrile
Show/Hide
|
C24H24N6O3
|
2
|
| 1 |
IC50 = 57.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702261
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-morpholinopropan-2-ol
Show/Hide
|
C27H32N6O4
|
2
|
| 1 |
IC50 = 57.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707205
|
N1-cyclopentyl-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 57.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667763
|
4-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)but-2-yn-1-ol
Show/Hide
|
C24H23N5O3
|
2
|
| 1 |
IC50 = 58.88 nM
|
|
|
| 2 |
IC50 = 6918.31 nM
|
|
|
|
CP0683693
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(2-methylpiperidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
|
2
|
| 1 |
IC50 = 58.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686566
|
N1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-N1-isopropylpropane-1,3-diamine hydrochloride
Show/Hide
|
C28H38ClN7O2
|
2
|
| 1 |
IC50 = 58.88 nM
|
|
|
| 2 |
IC50 = 6606.93 nM
|
|
|
|
CP0692301
|
N1-(3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N2-isopropylethane-1,2-diamine, 2,2,2-trifluoroacetate salt
Show/Hide
|
C29H36F3N7O4
|
2
|
| 1 |
IC50 = 60.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701302
|
2-(4-(3-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propyl)piperazin-1-yl)ethanol hydrochloride
Show/Hide
|
C33H47ClN8O3
|
2
|
| 1 |
IC50 = 60.26 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664760
|
2-((3,5-dimethoxyphenyl)(3-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 61.66 nM
|
|
|
| 2 |
IC50 = 9772.37 nM
|
|
|
|
CP0690264
|
1,1,2,2-tetradeuterio-2-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]ethanol
Show/Hide
|
C22H23N5O3
|
2
|
| 1 |
IC50 = 61.66 nM
|
|
|
| 2 |
IC50 = 6165.95 nM
|
|
|
|
CP0867047
|
1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-ol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 61.66 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657944
|
1-(4-(4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperazin-1-yl)piperidin-1-yl)ethanone
Show/Hide
|
C33H42N8O3
|
2
|
| 1 |
IC50 = 63.1 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744811
|
2-((3,5-dimethoxyphenyl)(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C24H27N5O5S
|
2
|
| 1 |
IC50 = 63.1 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702406
|
N1-(2,2-difluoroethyl)-N3-(3,5-dimethoxyphenyl)-N3-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H28F2N6O2
|
2
|
| 1 |
IC50 = 64.57 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735246
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 64.57 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664659
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(oxiran-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C23H23N5O3
|
2
|
| 1 |
IC50 = 66.07 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719341
|
2-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidin-4-yl)propan-2-ol
Show/Hide
|
C30H38N6O3
|
2
|
| 1 |
IC50 = 66.07 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0748512
|
N-(3-(3-aminopyridin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O2
|
2
|
| 1 |
IC50 = 66.07 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0720046
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(piperidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O2
|
2
|
| 1 |
IC50 = 67.61 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744803
|
1,1,2,2,3,3-hexadeuterio-3-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 67.61 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0850944
|
(S)-1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidine-3-carbonitrile hydrochloride
Show/Hide
|
C28H32ClN7O2
|
2
|
| 1 |
IC50 = 67.61 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664768
|
(R)-3-[{3-[1-(3-Aminopropyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}(3,5-dimethoxyphenyl)amino]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H27F3N6O3
|
2
|
| 1 |
IC50 = 69.18 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749420
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(5-ethyl-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-isopropylethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 69.18 nM
|
|
|
| 2 |
IC50 = 6760.83 nM
|
|
|
|
CP0757779
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H32ClN5O4
|
2
|
| 1 |
IC50 = 69.18 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649801
|
3-((3,5-dimethoxyphenyl)(3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C24H27N5O4
|
2
|
| 1 |
IC50 = 70.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657828
|
N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 72.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708034
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-((trimethylsilyl)methyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H35ClN6O2Si
|
2
|
| 1 |
IC50 = 72.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664767
|
methyl 2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)nicotinate
Show/Hide
|
C30H26N6O4
|
2
|
| 1 |
IC50 = 74.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698816
|
3-((3,5-dimethoxyphenyl)(3-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C27H31N5O4
|
2
|
| 1 |
IC50 = 74.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744813
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)ethanesulfonamide
Show/Hide
|
C24H28N6O4S
|
2
|
| 1 |
IC50 = 74.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692283
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(methylsulfonyl)ethyl)quinoxalin-6-amine
Show/Hide
|
C23H25N5O4S
|
2
|
| 1 |
IC50 = 75.86 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702107
|
N1-(2,2-difluoroethyl)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H26F2N6O2
|
2
|
| 1 |
IC50 = 75.86 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0746843
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(piperidin-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 75.86 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0688440
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 77.62 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704174
|
4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylamino)piperidine-1-sulfonamide
Show/Hide
|
C27H34N8O4S
|
2
|
| 1 |
IC50 = 77.62 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0672767
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3-fluoro-5-methoxyphenyl)-N2-isopropylethane-1,2-diamine hydrochloride
Show/Hide
|
C23H26ClFN6O
|
2
|
| 1 |
IC50 = 79.43 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707215
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-((2S,6R)-2,6-dimethylmorpholino)pyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C33H44ClN7O3
|
2
|
| 1 |
IC50 = 79.43 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0064283
|
Balversa
Show/Hide
|
C25H30N6O2
|
2
|
| 1 |
IC50 = 83.18 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707092
|
(S)-3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H26F3N5O3
|
2
|
| 1 |
IC50 = 83.18 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707214
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)acetamide
Show/Hide
|
C24H26N6O3
|
2
|
| 1 |
IC50 = 83.18 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673340
|
N-(2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H30N6O3
|
2
|
| 1 |
IC50 = 85.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673351
|
N'-[3,5-bis(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 85.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690289
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-isopropylpropanamide
Show/Hide
|
C26H30N6O3
|
2
|
| 1 |
IC50 = 85.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698845
|
N-(3-(2-amino-6-chloropyrimidin-4-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H23ClN8O2
|
2
|
| 1 |
IC50 = 85.11 nM
|
|
|
| 2 |
IC50 = 2041.74 nM
|
|
|
|
CP0726443
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyrimidin-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H23N7O2
|
2
|
| 1 |
IC50 = 85.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775911
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-methylethane-1,2-diamine hydrochloride
Show/Hide
|
C25H31ClN6O2
|
2
|
| 1 |
IC50 = 85.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702437
|
3-fluoro-5-((2-hydroxyethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-methylbenzamide
Show/Hide
|
C22H21FN6O2
|
2
|
| 1 |
IC50 = 87.1 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657887
|
tert-butyl 4-(4-(7-((3,5-dimethoxyphenyl)(2-(isopropylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Show/Hide
|
C34H45N7O4
|
2
|
| 1 |
IC50 = 89.13 nM
|
|
|
| 2 |
IC50 = 4466.84 nM
|
|
|
|
CP0704153
|
2-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylamino)acetamide
Show/Hide
|
C24H27N7O3
|
2
|
| 1 |
IC50 = 89.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0692219
|
N-isopropyl-N'-[3-methoxy-5-(trideuteriomethoxy)phenyl]-N'-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H29ClN6O2
|
2
|
| 1 |
IC50 = 91.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707097
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-fluoropyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H23FN6O2
|
2
|
| 1 |
IC50 = 93.33 nM
|
|
|
| 2 |
IC50 = 7943.28 nM
|
|
|
|
CP0664721
|
2-(4-(7-((3,5-dimethoxyphenyl)((3-methylisoxazol-5-yl)methyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C26H26N6O4
|
2
|
| 1 |
IC50 = 95.5 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672779
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(methylamino)propan-2-ol hydrochloride
Show/Hide
|
C24H29ClN6O3
|
2
|
| 1 |
IC50 = 95.5 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704722
|
N1-(3-(2-fluoroethoxy)-5-methoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C26H32ClFN6O2
|
2
|
| 1 |
IC50 = 95.5 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735326
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(2,2,2-trifluoroethylamino)propan-2-ol
Show/Hide
|
C25H27F3N6O3
|
2
|
| 1 |
IC50 = 95.5 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692230
|
(2S)-3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}propane-1,2-diol
Show/Hide
|
C23H25N5O4
|
2
|
| 1 |
IC50 = 97.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701253
|
3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)benzonitrile
Show/Hide
|
C30H24N6O2
|
2
|
| 1 |
IC50 = 97.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701290
|
N1-(3-fluoro-5-methoxyphenyl)-N3-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H29FN6O
|
2
|
| 1 |
IC50 = 97.72 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667756
|
(S)-1-[(3,5-Dimethoxyphenyl){3-[1-(1-methylethyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}amino]-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H32ClN5O4
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692268
|
N-(3,5-Dimethoxyphenyl)-N-[3-(3-methoxypyridin-2-yl)prop-2-yn-1-yl]-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726452
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((5-methylisoxazol-3-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C25H24N6O3
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657064
|
3-(3,5-dimethoxy-N-[3-[1-(2-methylsulfonylethyl)pyrazol-4-yl]quinoxalin-6-yl]anilino)propan-1-ol
Show/Hide
|
C25H29N5O5S
|
2
|
| 1 |
IC50 = 102.33 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0816363
|
3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H26F3N5O3
|
2
|
| 1 |
IC50 = 102.33 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657946
|
N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2,2,2-trifluoroethyl)propane-1,2-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 104.71 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688427
|
N-(3,5-Dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyrazin-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H23N7O2
|
2
|
| 1 |
IC50 = 104.71 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698847
|
N-(3,5-dimethoxyphenyl)-3-(1-isopropyl-1H-pyrazol-4-yl)-N-(3-(3-methoxypyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C31H30N6O3
|
2
|
| 1 |
IC50 = 104.71 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657882
|
N1-isopropyl-N2-(3-methoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C24H29ClN6O
|
2
|
| 1 |
IC50 = 107.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702428
|
N-((4-benzylmorpholin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C32H34N6O3
|
2
|
| 1 |
IC50 = 107.15 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0772358
|
4-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)butanenitrile
Show/Hide
|
C24H24N6O2
|
2
|
| 1 |
IC50 = 109.65 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692232
|
N1-(3-fluoro-5-methoxyphenyl)-N2-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C22H23FN6O
|
2
|
| 1 |
IC50 = 112.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0767027
|
2-(4-(7-((3-aminopropyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C25H29N7O3
|
2
|
| 1 |
IC50 = 112.2 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688423
|
(1R,4R)-N1-(3,5-dimethoxyphenyl)-N4-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)cyclohexane-1,4-diamine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 114.82 nM
|
|
|
| 2 |
IC50 = 5495.41 nM
|
|
|
|
CP0692289
|
N-(3-(3-aminopyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 114.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0744806
|
N-(3,5-dimethoxyphenyl)-N-(3-(6-methoxypyrimidin-4-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O3
|
2
|
| 1 |
IC50 = 114.82 nM
|
|
|
| 2 |
IC50 = 1905.46 nM
|
|
|
|
CP0776289
|
N1-(3,5-dimethoxyphenyl)-N2-ethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 114.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657880
|
1-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol
Show/Hide
|
C26H31N5O4
|
2
|
| 1 |
IC50 = 117.49 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673349
|
1-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H32ClN5O4
|
2
|
| 1 |
IC50 = 117.49 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664745
|
(R)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 120.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673344
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(4-methylpiperazin-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 120.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0888133
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-((2R,6R)-2,6-dimethyltetrahydro-2H-pyran-4-yl)pyrrolidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C34H45ClN6O3
|
2
|
| 1 |
IC50 = 120.23 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649784
|
N1-(2-aminobenzyl)-N2-(3,5-dimethoxycyclohexa-2,4-dienyl)-N1-isopropyl-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C32H39N7O2
|
2
|
| 1 |
IC50 = 123.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672785
|
3-((cyclopropylmethyl)(3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C27H30N6O3
|
2
|
| 1 |
IC50 = 123.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698928
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(piperidin-4-ylmethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H31ClN6O2
|
2
|
| 1 |
IC50 = 123.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704721
|
3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)oxazolidin-2-one
Show/Hide
|
C26H28N6O4
|
2
|
| 1 |
IC50 = 123.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707212
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypiperidin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O3
|
2
|
| 1 |
IC50 = 123.03 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692459
|
N-(3-chloro-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30Cl2N6O
|
2
|
| 1 |
IC50 = 125.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704712
|
5-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-methylpent-3-yn-2-ol
Show/Hide
|
C26H27N5O3
|
2
|
| 1 |
IC50 = 125.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673336
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C23H22F3N5O3
|
2
|
| 1 |
IC50 = 128.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702427
|
2-(4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperazin-1-yl)ethanol
Show/Hide
|
C28H35N7O3
|
2
|
| 1 |
IC50 = 128.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686564
|
(2S*)-3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C23H22F3N5O3
|
2
|
| 1 |
IC50 = 131.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717322
|
1-(3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidin-2-one
Show/Hide
|
C29H34N6O3
|
2
|
| 1 |
IC50 = 131.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0795336
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-2,2,2-trifluoroacetamide
Show/Hide
|
C24H23F3N6O3
|
2
|
| 1 |
IC50 = 131.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0841406
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(2-(isopropylamino)ethyl)amino)-5-methoxyphenol hydrochloride
Show/Hide
|
C23H27ClN6O2
|
2
|
| 1 |
IC50 = 131.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657885
|
N1-(2,2-difluoropropyl)-N3-(3,5-dimethoxyphenyl)-N3-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C26H30F2N6O2
|
2
|
| 1 |
IC50 = 134.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657886
|
N-(2-((1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H32ClN7O2
|
2
|
| 1 |
IC50 = 134.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667769
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 134.9 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692294
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-(trifluoromethyl)piperidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C29H33F3N6O2
|
2
|
| 1 |
IC50 = 138.04 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0756690
|
4-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-2-methylbutan-2-ol
Show/Hide
|
C25H29N5O3
|
2
|
| 1 |
IC50 = 138.04 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0683290
|
5-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1,3,4-oxadiazol-2-amine
Show/Hide
|
C23H22N8O3
|
2
|
| 1 |
IC50 = 141.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688422
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 141.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692296
|
3-((3,5-dimethoxyphenyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C25H29N5O3
|
2
|
| 1 |
IC50 = 141.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719349
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyridin-3-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C26H24N6O2
|
2
|
| 1 |
IC50 = 141.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0786939
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)propan-1-ol
Show/Hide
|
C22H23N5O3
|
2
|
| 1 |
IC50 = 141.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688438
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyrazin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H25N7O3
|
2
|
| 1 |
IC50 = 147.91 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702104
|
N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide hydrochloride
Show/Hide
|
C27H30ClF3N6O4
|
2
|
| 1 |
IC50 = 147.91 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702105
|
N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Show/Hide
|
C27H29F3N6O4
|
2
|
| 1 |
IC50 = 147.91 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775908
|
(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-yl acetate
Show/Hide
|
C26H29N5O5
|
2
|
| 1 |
IC50 = 147.91 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708031
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(isopropylamino)propan-2-ol
Show/Hide
|
C26H32N6O3
|
2
|
| 1 |
IC50 = 151.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688429
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-morpholinoethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H31ClN6O3
|
2
|
| 1 |
IC50 = 154.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692271
|
N-(3,5-dimethoxyphenyl)-N-((3-((isopropylamino)methyl)oxetan-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H34N6O3
|
2
|
| 1 |
IC50 = 154.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0809003
|
N-(3-(2-bromopyridin-3-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H23BrN6O2
|
2
|
| 1 |
IC50 = 154.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0848580
|
1-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)piperidine-3-carbonitrile
Show/Hide
|
C29H33N7O2
|
2
|
| 1 |
IC50 = 154.88 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707210
|
N-(3,5-Dimethoxyphenyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]propane-1,3-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 158.49 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673334
|
(S)-1-(2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)ethyl)pyrrolidine-3-carbonitrile
Show/Hide
|
C26H27N7O2
|
2
|
| 1 |
IC50 = 162.18 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688421
|
N-(3,5-dimethoxyphenyl)-N-[3-(1,1-dioxo-1,4-thiazinan-4-yl)propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O4S
|
2
|
| 1 |
IC50 = 169.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726309
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-ethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-methylethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 169.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726454
|
N1-(3,5-dimethoxyphenyl)-N2-(2-fluoroethyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H27FN6O2
|
2
|
| 1 |
IC50 = 169.82 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667758
|
3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-methoxy-N-methylpropanamide
Show/Hide
|
C25H28N6O4
|
2
|
| 1 |
IC50 = 173.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707096
|
(E/Z)-N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)allyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H27N7O3
|
2
|
| 1 |
IC50 = 173.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707162
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H35ClN6O2
|
2
|
| 1 |
IC50 = 173.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664784
|
3-((cyclopropylmethyl)(3-(1-isopropyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-fluoro-N-methylbenzamide
Show/Hide
|
C26H27FN6O
|
2
|
| 1 |
IC50 = 177.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686853
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-ol
Show/Hide
|
C24H27N5O4
|
2
|
| 1 |
IC50 = 177.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688394
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 177.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0735247
|
3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)azetidin-3-ol
Show/Hide
|
C26H26N6O3
|
2
|
| 1 |
IC50 = 177.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702434
|
(3S)-1-(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)pyrrolidine-3-carbonitrile
Show/Hide
|
C27H29N7O2
|
2
|
| 1 |
IC50 = 181.97 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704643
|
N-(2-(1,4-diazepan-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine, oxalate salt
Show/Hide
|
C29H35N7O6
|
2
|
| 1 |
IC50 = 181.97 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704645
|
N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
Show/Hide
|
C26H27F3N6O4
|
2
|
| 1 |
IC50 = 181.97 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667774
|
N-(3,5-dimethoxyphenyl)-3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)-N-((3-methylisoxazol-5-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C27H28N6O4
|
2
|
| 1 |
IC50 = 186.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704642
|
(S)-1-((R)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-hydroxypropyl)pyrrolidine-3-carbonitrile hydrochloride
Show/Hide
|
C28H32ClN7O3
|
2
|
| 1 |
IC50 = 186.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0831264
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(piperazin-1-yl)ethyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H32ClN7O2
|
2
|
| 1 |
IC50 = 186.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0831270
|
3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C25H26N6O2
|
2
|
| 1 |
IC50 = 186.21 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701265
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((2-methylthiazol-4-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C25H24N6O2S
|
2
|
| 1 |
IC50 = 190.55 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704127
|
3-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazol-5-yl)propan-1-ol
Show/Hide
|
C25H29N5O4
|
2
|
| 1 |
IC50 = 190.55 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704138
|
(S)-3-[{3-[1-(3-Aminopropyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}(3,5-dimethoxyphenyl)amino]-1,1,1-trifluoropropan-2-ol
Show/Hide
|
C25H27F3N6O3
|
2
|
| 1 |
IC50 = 190.55 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667760
|
(R)-1-((3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O4
|
2
|
| 1 |
IC50 = 194.98 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672901
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 194.98 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692457
|
2-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)-5-methoxyphenoxy)ethanol
Show/Hide
|
C27H32N6O3
|
2
|
| 1 |
IC50 = 194.98 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700890
|
N-[3,5-bis(trideuteriomethoxy)phenyl]-1,1,2,2,3,3-hexadeuterio-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N'-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 194.98 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701257
|
N-((1,3-dioxolan-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H25N5O4
|
2
|
| 1 |
IC50 = 194.98 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0864356
|
3-((3-(2-hydroxyethoxy)-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C24H27N5O4
|
2
|
| 1 |
IC50 = 194.98 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664732
|
N-(3,5-dimethoxyphenyl)-N-(2-(1-isopropylpiperidin-4-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H38N6O2
|
2
|
| 1 |
IC50 = 199.53 nM
|
|
|
| 2 |
IC50 = 5754.4 nM
|
|
|
|
CP0664740
|
N-(3,5-dimethoxyphenyl)-N-(2-ethoxyethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H27N5O3
|
2
|
| 1 |
IC50 = 199.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688441
|
1-(3-((3-fluoro-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)pyrrolidine-3-carbonitrile
Show/Hide
|
C27H28FN7O
|
2
|
| 1 |
IC50 = 199.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692261
|
(R)-N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 199.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702421
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C27H33ClN6O3
|
2
|
| 1 |
IC50 = 199.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0719348
|
(2S)-1-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-3-[(2,2,2-trifluoroethyl)amino]propan-2-ol
Show/Hide
|
C25H27F3N6O3
|
2
|
| 1 |
IC50 = 199.53 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0749416
|
2-((3-(2-fluoroethoxy)-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
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C23H24FN5O3
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2
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| 1 |
IC50 = 199.53 nM
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| 2 |
IC50 > 10000 nM
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CP0698837
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(E)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-one oxime
Show/Hide
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C23H24N6O3
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2
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| 1 |
IC50 = 204.17 nM
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| 2 |
IC50 > 10000 nM
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CP0707094
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N-(3,5-dimethoxyphenyl)-N-(prop-2-ynyl)-3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H29N5O3
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2
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| 1 |
IC50 = 204.17 nM
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| 2 |
IC50 > 10000 nM
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CP0744810
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3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propane-1,2-diol
Show/Hide
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C23H25N5O4
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2
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| 1 |
IC50 = 204.17 nM
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| 2 |
IC50 > 10000 nM
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CP0848579
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2-(4-(7-((3-aminopropyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
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C24H28N6O3
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2
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| 1 |
IC50 = 204.17 nM
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| 2 |
IC50 > 10000 nM
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CP0664776
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N-((6-bromopyridin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C26H23BrN6O2
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2
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| 1 |
IC50 = 208.93 nM
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| 2 |
IC50 > 10000 nM
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CP0700932
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N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-1-methylpiperidine-3-carboxamide
Show/Hide
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C29H35N7O3
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2
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| 1 |
IC50 = 208.93 nM
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| 2 |
IC50 > 10000 nM
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CP0707217
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N-(3,5-Dimethoxyphenyl)-N-{3-[1-(1-methylethyl)-1H-pyrazol-4-yl]quinoxalin-6-yl}-N'-(2,2,2-trifluoroethyl)propane-1,3-diamine hydrochloride
Show/Hide
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C27H32ClF3N6O2
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2
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| 1 |
IC50 = 208.93 nM
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| 2 |
IC50 > 10000 nM
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CP0701288
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N-((6-chloropyridin-3-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C26H23ClN6O2
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2
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| 1 |
IC50 = 213.8 nM
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| 2 |
IC50 > 10000 nM
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CP0717318
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2-((3,5-dimethoxy-2-methylphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
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C23H25N5O3
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2
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| 1 |
IC50 = 213.8 nM
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| 2 |
IC50 > 10000 nM
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CP0856841
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1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-ol
Show/Hide
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C25H29N5O3
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2
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| 1 |
IC50 = 213.8 nM
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| 2 |
IC50 > 10000 nM
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CP0649794
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2-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
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C23H25N5O4
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2
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| 1 |
IC50 = 218.78 nM
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| 2 |
IC50 > 10000 nM
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CP0672790
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cyclopropyl(4-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperazin-1-yl)methanone
Show/Hide
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C30H35N7O3
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2
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| 1 |
IC50 = 218.78 nM
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| 2 |
IC50 > 10000 nM
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CP0698815
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N-(3-(3-chloropyrazin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C27H22ClN7O2
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2
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| 1 |
IC50 = 218.78 nM
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| 2 |
IC50 = 3388.44 nM
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CP0702103
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N-(3-fluoro-5-methoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
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C25H28ClFN6O
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2
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| 1 |
IC50 = 218.78 nM
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| 2 |
IC50 > 10000 nM
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CP0803483
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N-[2-(4-Acetylpiperazin-1-yl)ethyl]-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H33N7O3
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2
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| 1 |
IC50 = 218.78 nM
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| 2 |
IC50 > 10000 nM
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CP0672906
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N-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propyl)-2,2,2-trifluoroacetamide
Show/Hide
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C25H25F3N6O3
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2
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| 1 |
IC50 = 223.87 nM
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| 2 |
IC50 > 10000 nM
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CP0692275
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2-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1-methyl-1H-pyrazol-5-yl)ethanol
Show/Hide
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C24H27N5O4
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2
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| 1 |
IC50 = 223.87 nM
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| 2 |
IC50 > 10000 nM
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CP0704180
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N1-(2-chloro-5-methoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
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C24H28Cl2N6O
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2
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| 1 |
IC50 = 223.87 nM
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| 2 |
IC50 > 10000 nM
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CP0686854
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3-{(Cyclopropylmethyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}-5-fluoro-N-methylbenzamide
Show/Hide
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C24H23FN6O
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2
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| 1 |
IC50 = 229.09 nM
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| 2 |
IC50 >= 10000 nM
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CP0701248
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N-((1H-pyrrolo[3,2-b]pyridin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H25N7O2
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2
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| 1 |
IC50 = 229.09 nM
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| 2 |
IC50 > 10000 nM
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CP0664743
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(S)-N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
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C23H26N6O2
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2
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| 1 |
IC50 = 234.42 nM
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| 2 |
IC50 > 10000 nM
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CP0701294
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(S)-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,2-diamine
Show/Hide
|
C23H26N6O2
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2
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| 1 |
IC50 = 234.42 nM
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| 2 |
IC50 > 10000 nM
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CP0717319
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N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2-chloro-5-methoxyphenyl)-N2-isopropylethane-1,2-diamine hydrochloride
Show/Hide
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C23H26Cl2N6O
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2
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| 1 |
IC50 = 239.88 nM
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| 2 |
IC50 > 10000 nM
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CP0822997
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N-[3-(6-Aminopyridin-2-yl)prop-2-yn-1-yl]-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H25N7O2
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2
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| 1 |
IC50 = 239.88 nM
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| 2 |
IC50 = 7585.78 nM
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CP0799271
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(Z)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-one oxime
Show/Hide
|
C23H24N6O3
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2
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| 1 |
IC50 = 245.47 nM
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| 2 |
IC50 > 10000 nM
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CP0657860
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N-(2-(3-aminopyrrolidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
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C26H32ClN7O2
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2
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| 1 |
IC50 = 251.19 nM
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| 2 |
IC50 > 10000 nM
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CP0692235
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(R)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-(2,2,2-trifluoroethylamino)propan-2-ol
Show/Hide
|
C25H27F3N6O3
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2
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| 1 |
IC50 = 251.19 nM
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| 2 |
IC50 > 10000 nM
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CP0692274
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N-(3,5-dimethoxyphenyl)-N-(2-fluoroethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C22H22FN5O2
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2
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| 1 |
IC50 = 251.19 nM
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| 2 |
IC50 = 3019.95 nM
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CP0692295
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(R)-(1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-2-yl)methanol
Show/Hide
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C27H32N6O3
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2
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| 1 |
IC50 = 251.19 nM
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| 2 |
IC50 > 10000 nM
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CP0698819
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N-(3,5-dimethoxyphenyl)-N-(2-(2,6-dimethylpiperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C29H36N6O2
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2
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| 1 |
IC50 = 251.19 nM
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| 2 |
IC50 > 10000 nM
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CP0758214
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(S)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1,1,1-trifluoropropan-2-yl acetate
Show/Hide
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C25H24F3N5O4
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2
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| 1 |
IC50 = 251.19 nM
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| 2 |
IC50 > 10000 nM
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CP0850943
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2-(4-(7-((3-fluoro-5-methoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
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C22H22FN5O3
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2
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| 1 |
IC50 = 251.19 nM
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| 2 |
IC50 > 10000 nM
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CP0657877
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2-[3-methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-5-(trideuteriomethoxy)anilino]ethanol
Show/Hide
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C22H23N5O3
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2
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| 1 |
IC50 = 257.04 nM
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| 2 |
IC50 > 3019.95 nM
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CP0667761
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(S)-1-((3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)-3-methoxypropan-2-ol hydrochloride
Show/Hide
|
C26H33ClN6O4
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2
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| 1 |
IC50 = 257.04 nM
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| 2 |
IC50 > 10000 nM
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CP0704644
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N-(3,5-dimethoxyphenyl)-N-((1-methyl-1H-imidazol-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C25H25N7O2
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2
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| 1 |
IC50 = 257.04 nM
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| 2 |
IC50 > 10000 nM
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CP0717313
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyridin-2-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C29H30N6O2
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2
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| 1 |
IC50 = 257.04 nM
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| 2 |
IC50 > 10000 nM
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CP0744804
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(S)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-yl acetate
Show/Hide
|
C26H29N5O5
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2
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| 1 |
IC50 = 269.15 nM
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| 2 |
IC50 > 10000 nM
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CP0751773
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N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H31ClF2N6O2
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2
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| 1 |
IC50 = 269.15 nM
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| 2 |
IC50 > 10000 nM
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CP0690265
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(6-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyridin-2-yl)methanol
Show/Hide
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C29H26N6O3
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2
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| 1 |
IC50 = 275.42 nM
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| 2 |
IC50 = 8709.64 nM
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CP0719608
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2-(4-(7-((3,5-dimethoxyphenyl)(3-hydroxypropyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C25H28N6O4
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2
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| 1 |
IC50 = 275.42 nM
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| 2 |
IC50 > 10000 nM
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CP0726561
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H23N5O3
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2
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| 1 |
IC50 = 275.42 nM
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| 2 |
IC50 > 10000 nM
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CP0863057
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N-(3,5-dimethoxyphenyl)-N-(2-((3R,5S)-3,5-dimethylpiperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O2
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2
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| 1 |
IC50 = 275.42 nM
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| 2 |
IC50 > 10000 nM
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CP0664753
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3-((2-hydroxyethyl)(3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C25H28N6O4
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2
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| 1 |
IC50 = 281.84 nM
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| 2 |
IC50 > 10000 nM
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CP0701274
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2-(3,5-dimethoxy-N-[7-[1-(trideuteriomethyl)pyrazol-4-yl]quinoxalin-2-yl]anilino)ethanol
Show/Hide
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C22H23N5O3
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2
|
| 1 |
IC50 = 281.84 nM
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| 2 |
IC50 > 10000 nM
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CP0850937
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1-(3,3-difluoropyrrolidin-1-yl)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-ol hydrochloride
Show/Hide
|
C27H31ClF2N6O3
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2
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| 1 |
IC50 = 281.84 nM
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| 2 |
IC50 > 10000 nM
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CP0701267
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2-(4-(7-(((5-chlorothiophen-2-yl)methyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C26H24ClN5O3S
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2
|
| 1 |
IC50 = 288.4 nM
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| 2 |
IC50 > 10000 nM
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CP0751761
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tert-butyl 4-(4-(7-((3,5-dimethoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
Show/Hide
|
C31H38N6O5
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2
|
| 1 |
IC50 = 288.4 nM
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| 2 |
IC50 > 10000 nM
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CP0683691
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N-(3,5-dimethoxyphenyl)-N-(2-methoxyethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 295.12 nM
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| 2 |
IC50 > 10000 nM
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CP0692293
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N-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)cyclopropanecarboxamide
Show/Hide
|
C26H28N6O3
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2
|
| 1 |
IC50 = 295.12 nM
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| 2 |
IC50 > 10000 nM
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CP0698839
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Ethyl 1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidine-4-carboxylate
Show/Hide
|
C30H36N6O4
|
2
|
| 1 |
IC50 = 302 nM
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| 2 |
IC50 > 10000 nM
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CP0744814
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)propane-1,3-diamine
Show/Hide
|
C22H24N6O2
|
2
|
| 1 |
IC50 = 302 nM
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| 2 |
IC50 > 10000 nM
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CP0690539
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(piperidin-4-yl)prop-2-ynyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H31ClN6O2
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2
|
| 1 |
IC50 = 309.03 nM
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| 2 |
IC50 = 6309.57 nM
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CP0692276
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6-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)picolinonitrile
Show/Hide
|
C29H23N7O2
|
2
|
| 1 |
IC50 = 309.03 nM
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| 2 |
IC50 > 10000 nM
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CP0726453
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2-(4-(7-((3,5-dimethoxyphenyl)(2-(methylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C25H29N7O3
|
2
|
| 1 |
IC50 = 309.03 nM
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| 2 |
IC50 > 10000 nM
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CP0751771
|
2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)ethanol
Show/Hide
|
C21H21N5O3
|
2
|
| 1 |
IC50 = 309.03 nM
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| 2 |
IC50 > 10000 nM
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CP0822984
|
(E)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-one oxime
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 309.03 nM
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| 2 |
IC50 > 10000 nM
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CP0692255
|
(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)phenyl)methanol
Show/Hide
|
C27H32N6O2
|
2
|
| 1 |
IC50 = 316.23 nM
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| 2 |
IC50 > 10000 nM
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CP0657881
|
3-((2-hydroxyethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
Show/Hide
|
C21H21N5O3
|
2
|
| 1 |
IC50 = 323.59 nM
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| 2 |
IC50 > 10000 nM
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CP0672905
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(methylamino)pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
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C28H36ClN7O2
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2
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| 1 |
IC50 = 323.59 nM
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| 2 |
IC50 > 10000 nM
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CP0673338
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-ethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
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C23H26N6O2
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2
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| 1 |
IC50 = 323.59 nM
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| 2 |
IC50 > 10000 nM
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CP0757781
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2-(4-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1H-1,2,3-triazol-1-yl)ethanol
Show/Hide
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C25H26N8O3
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2
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| 1 |
IC50 = 323.59 nM
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| 2 |
IC50 > 10000 nM
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CP0672827
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N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
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C26H30ClF3N6O2
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2
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| 1 |
IC50 = 346.74 nM
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| 2 |
IC50 > 10000 nM
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CP0701264
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N-((5-chlorothiophen-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C25H22ClN5O2S
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2
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| 1 |
IC50 = 346.74 nM
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| 2 |
IC50 > 10000 nM
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CP0746822
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4-(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)piperazin-2-one
Show/Hide
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C26H29N7O3
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2
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| 1 |
IC50 = 354.81 nM
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| 2 |
IC50 > 10000 nM
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CP0775909
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2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
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C26H28N6O3
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2
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| 1 |
IC50 = 354.81 nM
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| 2 |
IC50 > 10000 nM
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CP0664717
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-2-yl)methyl)quinoxalin-6-amine
Show/Hide
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C25H27N5O3
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2
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| 1 |
IC50 = 363.08 nM
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| 2 |
IC50 > 10000 nM
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CP0673333
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N-(3,5-dimethoxyphenyl)-N-(2-(3-(dimethylamino)pyrrolidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H35N7O2
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2
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| 1 |
IC50 = 363.08 nM
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| 2 |
IC50 > 10000 nM
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CP0698830
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3-((3-fluoro-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
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C22H22FN5O2
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2
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| 1 |
IC50 = 363.08 nM
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| 2 |
IC50 > 10000 nM
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CP0702259
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(piperidin-4-yl)ethyl)quinoxalin-6-amine
Show/Hide
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C27H32N6O2
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2
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| 1 |
IC50 = 363.08 nM
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| 2 |
IC50 > 10000 nM
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CP0708033
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((3-methyloxetan-3-yl)methyl)quinoxalin-6-amine
Show/Hide
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C25H27N5O3
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2
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| 1 |
IC50 = 363.08 nM
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| 2 |
IC50 > 10000 nM
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CP0690290
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((3-methylisoxazol-5-yl)methyl)quinoxalin-6-amine
Show/Hide
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C25H24N6O3
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2
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| 1 |
IC50 = 380.19 nM
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| 2 |
IC50 > 10000 nM
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CP0746842
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N-(3,5-dimethoxyphenyl)-N-((6-methoxypyridin-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C27H26N6O3
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2
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| 1 |
IC50 = 380.19 nM
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| 2 |
IC50 > 10000 nM
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CP0773267
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3-[(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)amino]propanenitrile
Show/Hide
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C25H27N7O2
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2
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| 1 |
IC50 = 380.19 nM
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| 2 |
IC50 > 10000 nM
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CP0692281
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N-(3,5-dimethoxyphenyl)-N-ethyl-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C22H23N5O2
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2
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| 1 |
IC50 = 389.05 nM
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| 2 |
IC50 > 10000 nM
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CP0698846
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N1-(3,5-dimethoxyphenyl)-N1-(3-(5-((dimethylamino)methyl)-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-isopropylethane-1,2-diamine
Show/Hide
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C28H37N7O2
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2
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| 1 |
IC50 = 389.05 nM
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| 2 |
IC50 > 10000 nM
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CP0698927
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N-((2H-1,2,3-triazol-4-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C23H22N8O2
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2
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| 1 |
IC50 = 389.05 nM
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| 2 |
IC50 > 10000 nM
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CP0704646
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-propyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine hydrochloride
Show/Hide
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C24H29ClN6O2
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2
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| 1 |
IC50 = 389.05 nM
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| 2 |
IC50 > 10000 nM
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CP0708037
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-4-yl)propyl)quinoxalin-6-amine
Show/Hide
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C28H28N6O2
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2
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| 1 |
IC50 = 389.05 nM
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| 2 |
IC50 >= 10000 nM
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CP0664769
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(R)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propane-1,2-diol
Show/Hide
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C23H25N5O4
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2
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| 1 |
IC50 = 416.87 nM
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| 2 |
IC50 > 10000 nM
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CP0692461
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N1-cyclopropyl-N2-(3,5-dimethoxyphenyl)-N2-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
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C25H28N6O2
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2
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| 1 |
IC50 = 416.87 nM
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| 2 |
IC50 > 10000 nM
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CP0756693
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N-(2-(1H-pyrazol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
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C25H26ClN7O2
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2
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| 1 |
IC50 = 416.87 nM
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| 2 |
IC50 > 10000 nM
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CP0775902
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1-amino-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-2-ol
Show/Hide
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C23H26N6O3
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2
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| 1 |
IC50 = 416.87 nM
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| 2 |
IC50 > 10000 nM
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CP0850935
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H33N5O3
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2
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| 1 |
IC50 = 416.87 nM
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| 2 |
IC50 > 10000 nM
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CP0864355
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3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(cyclopropylmethyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
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C24H24N6O2
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2
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| 1 |
IC50 = 416.87 nM
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| 2 |
IC50 > 10000 nM
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CP0672845
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanamide
Show/Hide
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C23H24N6O3
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2
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| 1 |
IC50 = 426.58 nM
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| 2 |
IC50 > 10000 nM
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CP0649799
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl methylcarbamate
Show/Hide
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C24H26N6O4
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2
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| 1 |
IC50 = 436.52 nM
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| 2 |
IC50 > 10000 nM
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CP0672724
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N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C24H25F3N6O2
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2
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| 1 |
IC50 = 436.52 nM
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| 2 |
IC50 > 10000 nM
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CP0683435
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N-(3,5-dimethoxyphenyl)-N-(furan-2-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C25H23N5O3
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2
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| 1 |
IC50 = 436.52 nM
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| 2 |
IC50 > 10000 nM
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CP0688373
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2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N,N-dimethylacetamide
Show/Hide
|
C27H30N6O3
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2
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| 1 |
IC50 = 436.52 nM
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| 2 |
IC50 > 10000 nM
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CP0751769
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3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanenitrile
Show/Hide
|
C23H22N6O2
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2
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| 1 |
IC50 = 436.52 nM
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| 2 |
IC50 > 10000 nM
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CP0657940
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(oxetan-3-yl)quinoxalin-6-amine
Show/Hide
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C23H23N5O3
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2
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| 1 |
IC50 = 446.68 nM
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| 2 |
IC50 > 10000 nM
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CP0692270
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3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
Show/Hide
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C23H23N5O2
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2
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| 1 |
IC50 = 446.68 nM
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| 2 |
IC50 > 10000 nM
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CP0704130
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(piperazin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
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2
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| 1 |
IC50 = 446.68 nM
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| 2 |
IC50 > 10000 nM
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CP0720054
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N-(3,5-dimethoxyphenyl)-N-((3-methoxypiperidin-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H33ClN6O3
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2
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| 1 |
IC50 = 446.68 nM
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| 2 |
IC50 > 10000 nM
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CP0692297
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N-(3,5-dimethoxyphenyl)-N-(3-((2S,6R)-2,6-dimethylmorpholino)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O3
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2
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| 1 |
IC50 = 457.09 nM
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| 2 |
IC50 > 10000 nM
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CP0744808
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H34N6O4S
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2
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| 1 |
IC50 = 457.09 nM
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| 2 |
IC50 > 10000 nM
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CP0775913
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((1-methylpiperidin-4-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O2
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2
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| 1 |
IC50 = 457.09 nM
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| 2 |
IC50 > 10000 nM
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CP0744816
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((1R,2R)-2-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)cyclopropyl)methanol
Show/Hide
|
C25H27N5O3
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2
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| 1 |
IC50 = 467.74 nM
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| 2 |
IC50 > 10000 nM
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CP0664763
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4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)nicotinonitrile
Show/Hide
|
C29H23N7O2
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2
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| 1 |
IC50 = 478.63 nM
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| 2 |
IC50 = 1096.48 nM
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CP0673342
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N-(3,5-dimethoxyphenyl)-N-(3-(2-methyl-1H-imidazol-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H29N7O2
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2
|
| 1 |
IC50 = 478.63 nM
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| 2 |
IC50 > 10000 nM
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CP0799261
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N-(3,5-dimethoxyphenyl)-N-(furo[3,2-b]pyridin-2-ylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H24N6O3
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2
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| 1 |
IC50 = 478.63 nM
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| 2 |
IC50 = 1862.09 nM
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CP0649786
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N-(3,5-dimethoxyphenyl)-N-methyl-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C21H21N5O2
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2
|
| 1 |
IC50 = 501.19 nM
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| 2 |
IC50 > 10000 nM
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CP0749421
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N-(2,6-dichloro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C23H19Cl2N5O2
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2
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| 1 |
IC50 = 501.19 nM
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| 2 |
IC50 > 10000 nM
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CP0698821
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)butane-1,4-diamine
Show/Hide
|
C24H28N6O2
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2
|
| 1 |
IC50 = 512.86 nM
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| 2 |
IC50 > 10000 nM
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CP0688434
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2-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide
Show/Hide
|
C26H28N8O4S
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2
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| 1 |
IC50 = 524.81 nM
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| 2 |
IC50 > 10000 nM
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CP0701307
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(Z)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrimidin-2-yl)allyl)quinoxalin-6-amine
Show/Hide
|
C27H25N7O2
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2
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| 1 |
IC50 = 524.81 nM
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| 2 |
IC50 > 10000 nM
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CP0692226
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N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C32H39ClF2N6O3
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2
|
| 1 |
IC50 = 537.03 nM
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| 2 |
IC50 > 10000 nM
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CP0675654
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1-(3-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}propyl)pyrrolidin-2-one
Show/Hide
|
C27H30N6O3
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2
|
| 1 |
IC50 = 549.54 nM
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| 2 |
IC50 > 10000 nM
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CP0692265
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,2-trifluoroethyl)ethane-1,2-diamine
Show/Hide
|
C24H25F3N6O2
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2
|
| 1 |
IC50 = 549.54 nM
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| 2 |
IC50 > 10000 nM
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CP0708038
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrimidin-2-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C27H27N7O2
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2
|
| 1 |
IC50 = 549.54 nM
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| 2 |
IC50 = 2570.4 nM
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CP0888134
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N-(3-(3,3-difluoroazetidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H28F2N6O2
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2
|
| 1 |
IC50 = 549.54 nM
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| 2 |
IC50 > 10000 nM
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CP0864935
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N-(3,5-dimethoxyphenyl)-N-(2-((3R,5R)-3,5-dimethylpiperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H37ClN6O2
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2
|
| 1 |
IC50 = 562.34 nM
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| 2 |
IC50 > 10000 nM
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CP0673346
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N-(3,5-dimethoxyphenyl)-N-(3-(2,5-dimethyl-1H-imidazol-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H32ClN7O2
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2
|
| 1 |
IC50 = 588.84 nM
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| 2 |
IC50 > 10000 nM
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CP0772378
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N'-[3-fluoro-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C21H21FN6O
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2
|
| 1 |
IC50 = 588.84 nM
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| 2 |
IC50 > 10000 nM
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CP0707089
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N1-(3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine hydrochloride
Show/Hide
|
C27H33ClF3N7O2
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2
|
| 1 |
IC50 = 602.56 nM
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| 2 |
IC50 = 9120.11 nM
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CP0744815
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N-(3,5-dimethoxyphenyl)-N-(2-((2S,6R)-2,6-dimethylmorpholino)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C28H35ClN6O3
|
2
|
| 1 |
IC50 = 616.6 nM
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| 2 |
IC50 > 10000 nM
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CP0664761
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2-((3,5-dimethoxyphenyl)(3-(5-ethyl-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C24H27N5O3
|
2
|
| 1 |
IC50 = 630.96 nM
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| 2 |
IC50 = 9772.37 nM
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CP0688444
|
(Z)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-one oxime
Show/Hide
|
C25H28N6O3
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700936
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C26H29N5O3
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701269
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(thiophen-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H23N5O2S
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
IC50 > 3019.95 nM
|
|
|
|
CP0749418
|
3-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)oxazolidin-2-one
Show/Hide
|
C25H26N6O4
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0829305
|
2-((3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)ethanol hydrochloride
Show/Hide
|
C24H29ClN6O3
|
2
|
| 1 |
IC50 = 630.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0722354
|
1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-methylpropan-2-ol
Show/Hide
|
C24H27N5O3
|
2
|
| 1 |
IC50 = 645.65 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775912
|
N-(3,5-dimethoxyphenyl)-N-((2-methylthiazol-4-yl)methyl)-3-(1-(2-(piperazin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H34N8O2S
|
2
|
| 1 |
IC50 = 645.65 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672903
|
3-((3-fluoro-5-methoxyphenyl)(3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
|
C23H24FN5O3
|
2
|
| 1 |
IC50 = 660.69 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664722
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetic acid hydrochloride
Show/Hide
|
C22H22ClN5O4
|
2
|
| 1 |
IC50 = 676.08 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701296
|
(1S,4S)-tert-butyl 5-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
Show/Hide
|
C32H39N7O4
|
2
|
| 1 |
IC50 = 676.08 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704634
|
2-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(cyclopropylmethyl)amino)-5-methoxyphenoxy)ethanol
Show/Hide
|
C24H25N5O3
|
2
|
| 1 |
IC50 = 676.08 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701304
|
4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)tetrahydro-2H-pyran-4-ol
Show/Hide
|
C28H29N5O4
|
2
|
| 1 |
IC50 = 691.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0775910
|
3-{4-[3-(4-{7-[(Cyclopropylmethyl)(3,5-dimethoxyphenyl)amino]quinoxalin-2-yl}-1H-pyrazol-1-yl)propyl]piperazin-1-yl}propan-1-ol hydrochloride
Show/Hide
|
C33H44ClN7O3
|
2
|
| 1 |
IC50 = 691.83 nM
|
|
|
| 2 |
IC50 = 5623.41 nM
|
|
|
|
CP0667778
|
N-[2-[4-[7-[N-(cyclopropylmethyl)-3,5-dimethoxy-anilino]quinoxalin-2-yl]pyrazol-1-yl]ethyl]methanesulfonamide
Show/Hide
|
C26H30N6O4S
|
2
|
| 1 |
IC50 = 724.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672777
|
N-allyl-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H23N5O2
|
2
|
| 1 |
IC50 = 724.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672828
|
N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H30N6O3
|
2
|
| 1 |
IC50 = 724.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717317
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-methylacetamide
Show/Hide
|
C23H24N6O3
|
2
|
| 1 |
IC50 = 724.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667765
|
methyl 2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyrimidine-4-carboxylate
Show/Hide
|
C29H25N7O4
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 = 4168.69 nM
|
|
|
|
CP0672907
|
N-(2-(4-aminopiperidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686855
|
N-(3,5-dimethoxyphenyl)-N-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H37N7O2
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 = 5754.4 nM
|
|
|
|
CP0726549
|
1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidin-2-one
Show/Hide
|
C26H28N6O3
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726555
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-methoxyethyl)acetamide
Show/Hide
|
C28H32N6O4
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0756691
|
(R/S)-1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)piperidine-3-carbonitrile
Show/Hide
|
C28H31N7O2
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0805802
|
(Z)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methoxypropan-2-one oxime
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 741.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649788
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
IC50 = 758.58 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667755
|
(R/S)-3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)pyrrolidin-3-ol
Show/Hide
|
C27H28N6O3
|
2
|
| 1 |
IC50 = 776.25 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649796
|
1-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-3-(piperidin-1-yl)propan-2-ol
Show/Hide
|
C31H38N6O3
|
2
|
| 1 |
IC50 = 794.33 nM
|
|
|
| 2 |
IC50 = 6918.31 nM
|
|
|
|
CP0672775
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((1-methylpiperidin-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H36N6O2
|
2
|
| 1 |
IC50 = 794.33 nM
|
|
|
| 2 |
IC50 = 8912.51 nM
|
|
|
|
CP0692269
|
N-(3,5-dimethoxyphenyl)-N-(2-(2,5-dimethyl-1H-imidazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H29N7O2
|
2
|
| 1 |
IC50 = 794.33 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0804304
|
2-[4-(7-{(Cyclopropylmethyl)[3-(2-hydroxyethoxy)-5-methoxyphenyl]amino}quinoxalin-2-yl)-1H-pyrazol-1-yl]ethanol hydrochloride
Show/Hide
|
C26H30ClN5O4
|
2
|
| 1 |
IC50 = 794.33 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0873125
|
2-(4-(7-((2-aminoethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol hydrochloride
Show/Hide
|
C23H27ClN6O3
|
2
|
| 1 |
IC50 = 794.33 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649793
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(piperidin-4-ylmethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H34N6O2
|
2
|
| 1 |
IC50 = 812.83 nM
|
|
|
| 2 |
IC50 = 8511.38 nM
|
|
|
|
CP0673345
|
N-(3,5-dimethoxyphenyl)-N-((1,5-dimethyl-1H-pyrazol-3-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N7O2
|
2
|
| 1 |
IC50 = 812.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704651
|
3-((2-aminoethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenol
Show/Hide
|
C21H22N6O2
|
2
|
| 1 |
IC50 = 812.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701263
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((4-methoxypiperidin-4-yl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H36N6O3
|
2
|
| 1 |
IC50 = 831.76 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702260
|
1-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)-2-methylpropan-2-ol
Show/Hide
|
C23H25N5O3
|
2
|
| 1 |
IC50 = 831.76 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717312
|
(R/S)-3-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)tetrahydrofuran-3-ol
Show/Hide
|
C27H27N5O4
|
2
|
| 1 |
IC50 = 831.76 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649803
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-1-(3-hydroxypyrrolidin-1-yl)ethanone
Show/Hide
|
C29H32N6O4
|
2
|
| 1 |
IC50 = 851.14 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692273
|
3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-hydroxypropyl)amino)-5-methoxyphenol
Show/Hide
|
C21H21N5O3
|
2
|
| 1 |
IC50 = 851.14 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657878
|
N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H29ClF2N6O2
|
2
|
| 1 |
IC50 = 870.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688424
|
N-(3-(3,3-difluoropyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H28F2N6O2
|
2
|
| 1 |
IC50 = 870.96 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657835
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(piperidin-1-yl)pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
|
C32H41N7O2
|
2
|
| 1 |
IC50 = 912.01 nM
|
|
|
| 2 |
IC50 = 9332.54 nM
|
|
|
|
CP0701308
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(4-methylpyridin-2-yl)acetamide
Show/Hide
|
C28H27N7O3
|
2
|
| 1 |
IC50 = 912.01 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672783
|
2-(4-(2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethyl)piperazin-1-yl)ethanol hydrochloride
Show/Hide
|
C31H40ClN7O3
|
2
|
| 1 |
IC50 = 977.24 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702438
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,2-trifluoroethyl)propane-1,2-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 977.24 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0061016
|
3-(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenol
Show/Hide
|
C17H18N4O
|
1
|
| 1 |
IC50 = 990 nM
|
|
|
|
CP0649791
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N,2-dimethylpropanamide
Show/Hide
|
C28H32N6O3
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649792
|
ethyl 2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetate
Show/Hide
|
C24H25N5O4
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0686573
|
N-(3,5-dimethoxyphenyl)-N-(3-(4-methoxypyrimidin-2-yl)propyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H29N7O3
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701295
|
3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(2,2,2-trifluoroethylamino)propyl)amino)phenol
Show/Hide
|
C24H25F3N6O2
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0771748
|
3-((2-aminoethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C23H25N7O2
|
2
|
| 1 |
IC50 = 1023.29 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704125
|
N-(3,5-dimethoxyphenyl)-N-(3-(2-methoxypyridin-4-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
2
|
| 1 |
IC50 = 1047.13 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649797
|
2-(3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenoxy)ethanol
Show/Hide
|
C25H27N5O3
|
2
|
| 1 |
IC50 = 1071.52 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701255
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)butane-1,2-diamine
Show/Hide
|
C28H36N6O2
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701259
|
N1-(3,5-dimethoxyphenyl)-N2-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C23H26N6O2
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704630
|
(S)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyrrolidin-2-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C25H28N6O2
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0748515
|
(Z)-N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)allyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O3
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0762383
|
N1-(3,5-dimethoxyphenyl)-N2-isopropyl-3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)butane-1,2-diamine hydrochloride
Show/Hide
|
C28H37ClN6O2
|
2
|
| 1 |
IC50 = 1096.48 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0657876
|
2-((2-chloro-5-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C21H20ClN5O2
|
2
|
| 1 |
IC50 = 1122.02 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
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CP0664738
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H23N5O2
|
2
|
| 1 |
IC50 = 1122.02 nM
|
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|
| 2 |
IC50 > 10000 nM
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CP0673329
|
N-(3,5-dimethoxyphenyl)-N-((2-methylthiazol-4-yl)methyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H22N6O2S
|
2
|
| 1 |
IC50 = 1122.02 nM
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| 2 |
IC50 > 10000 nM
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CP0672902
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(piperazin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H36ClN7O2
|
2
|
| 1 |
IC50 = 1148.15 nM
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| 2 |
IC50 > 10000 nM
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CP0698820
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N-(2-(3-aminopiperidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N7O2
|
2
|
| 1 |
IC50 = 1148.15 nM
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| 2 |
IC50 > 10000 nM
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CP0717784
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N-(3,5-Dimethoxyphenyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
Show/Hide
|
C22H24N6O2
|
2
|
| 1 |
IC50 = 1148.15 nM
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| 2 |
IC50 > 10000 nM
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CP0649804
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C23H21N5O2
|
2
|
| 1 |
IC50 = 1174.9 nM
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| 2 |
IC50 > 10000 nM
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CP0664786
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C24H28N6O4S
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2
|
| 1 |
IC50 = 1174.9 nM
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| 2 |
IC50 > 10000 nM
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CP0702432
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N-(3,5-dimethoxyphenyl)-N-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H37N7O2
|
2
|
| 1 |
IC50 = 1174.9 nM
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| 2 |
IC50 > 10000 nM
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CP0649798
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2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-hydroxyethyl)acetamide
Show/Hide
|
C27H30N6O4
|
2
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| 1 |
IC50 = 1202.26 nM
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| 2 |
IC50 > 10000 nM
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CP0657942
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2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-fluoro-5-methoxyphenyl)amino)ethanol
Show/Hide
|
C20H18FN5O2
|
2
|
| 1 |
IC50 = 1202.26 nM
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| 2 |
IC50 > 10000 nM
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CP0672780
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3-((3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C29H35N7O3
|
2
|
| 1 |
IC50 = 1202.26 nM
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| 2 |
IC50 > 10000 nM
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CP0686864
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3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(2,2,2-trifluoroethylamino)propyl)amino)-5-methoxyphenol hydrochloride
Show/Hide
|
C23H24ClF3N6O2
|
2
|
| 1 |
IC50 = 1202.26 nM
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| 2 |
IC50 > 10000 nM
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CP0701311
|
2-(3-((cyclopropylmethyl)(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenoxy)ethanol
Show/Hide
|
C27H31N5O5S
|
2
|
| 1 |
IC50 = 1202.26 nM
|
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| 2 |
IC50 > 10000 nM
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CP0704632
|
N1-(3,5-dimethoxyphenyl)-N2-methyl-N1-(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H30N6O4S
|
2
|
| 1 |
IC50 = 1202.26 nM
|
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| 2 |
IC50 > 10000 nM
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CP0864428
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2-hydroxyethyl)acetamide
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 1202.26 nM
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| 2 |
IC50 > 10000 nM
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|
|
|
CP0019908
|
BDBM50242742
Show/Hide
|
C30H40ClN7O3S
|
1
|
| 1 |
IC50 = 1216 nM
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CP0667779
|
3-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)propane-1,2-diol
Show/Hide
|
C26H29N5O4
|
2
|
| 1 |
IC50 = 1318.26 nM
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| 2 |
IC50 = 8511.38 nM
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CP0702096
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(piperidin-4-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C30H37ClN6O2
|
2
|
| 1 |
IC50 = 1318.26 nM
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|
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| 2 |
IC50 = 5623.41 nM
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CP0720055
|
2-(4-(3-((2-aminoethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-6-yl)-1H-pyrazol-1-yl)-N-methylacetamide
Show/Hide
|
C24H27N7O3
|
2
|
| 1 |
IC50 = 1318.26 nM
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| 2 |
IC50 > 10000 nM
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CP0698824
|
N-(3,5-Dimethoxyphenyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]-N'-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C25H27F3N6O2
|
2
|
| 1 |
IC50 = 1348.96 nM
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| 2 |
IC50 > 10000 nM
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CP0701300
|
4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)picolinonitrile
Show/Hide
|
C29H23N7O2
|
2
|
| 1 |
IC50 = 1412.54 nM
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|
| 2 |
IC50 = 6760.83 nM
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CP0702108
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(pyridin-4-ylmethyl)quinoxalin-6-amine
Show/Hide
|
C26H24N6O2
|
2
|
| 1 |
IC50 = 1412.54 nM
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|
| 2 |
IC50 > 10000 nM
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CP0672784
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C29H35ClN6O2
|
2
|
| 1 |
IC50 = 1445.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
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|
CP0686497
|
N-(3,5-dimethoxyphenyl)-N-(2-(2,4-dimethyl-1H-imidazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C27H30ClN7O2
|
2
|
| 1 |
IC50 = 1479.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0850942
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(methylamino)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H30N6O2
|
2
|
| 1 |
IC50 = 1479.11 nM
|
|
|
| 2 |
IC50 = 6456.54 nM
|
|
|
|
CP0667762
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((1-methyl-1H-pyrrolo[3,2-b]pyridin-2-yl)methyl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O2
|
2
|
| 1 |
IC50 = 1513.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0701268
|
2-(3-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)azetidin-1-yl)ethanol
Show/Hide
|
C28H32N6O3
|
2
|
| 1 |
IC50 = 1513.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0719253
|
N-(3,5-dimethoxyphenyl)-N-(2-(2-methyl-1H-imidazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N7O2
|
2
|
| 1 |
IC50 = 1513.56 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0701256
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C28H32N6O2
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 = 6456.54 nM
|
|
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|
CP0720061
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(1-(2-(methylsulfonyl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)propane-1,3-diamine
Show/Hide
|
C25H30N6O4S
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0726455
|
N-(2-(4,4-difluoropiperidin-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H30F2N6O2
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0756689
|
N-((5-chlorothiophen-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(piperazin-1-yl)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C30H33Cl2N7O2S
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 = 2754.23 nM
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CP0851333
|
4-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)piperidin-4-ol
Show/Hide
|
C26H30N6O3
|
2
|
| 1 |
IC50 = 1584.89 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0657861
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2-(pyrrolidin-1-yl)ethyl)acetamide
Show/Hide
|
C28H33N7O3
|
2
|
| 1 |
IC50 = 1621.81 nM
|
|
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| 2 |
IC50 > 10000 nM
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CP0667777
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-(methylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-methylacetamide hydrochloride
Show/Hide
|
C25H30ClN7O3
|
2
|
| 1 |
IC50 = 1621.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0692266
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-methoxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H29N5O3
|
2
|
| 1 |
IC50 = 1621.81 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
|
|
CP0657066
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C21H23ClN6O2
|
2
|
| 1 |
IC50 = 1659.59 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0698826
|
N-(3,5-dimethoxyphenyl)-N-((1-isopropylpiperidin-4-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O2
|
2
|
| 1 |
IC50 = 1698.24 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664782
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(3,5-dimethoxyphenyl)-N2-methylethane-1,2-diamine
Show/Hide
|
C22H24N6O2
|
2
|
| 1 |
IC50 = 1737.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0864427
|
3-((3-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-hydroxypropyl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C25H28N6O4
|
2
|
| 1 |
IC50 = 1737.8 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701260
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(3-morpholinopropyl)-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C30H37ClN6O3
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707159
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-isopropylacetamide
Show/Hide
|
C25H28N6O3
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707163
|
2-((3,5-dimethoxyphenyl)(3-(5-((dimethylamino)methyl)-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C25H30N6O3
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0708030
|
2-((3-ethoxy-5-fluorophenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C22H22FN5O2
|
2
|
| 1 |
IC50 = 1778.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667759
|
N-(3,5-dimethoxyphenyl)-N-((4,6-dimethoxypyrimidin-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H27N7O4
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692300
|
2-(4-(7-((3,5-dimethoxyphenyl)(2-(methylamino)ethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C24H28N6O3
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0748526
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(3-(trifluoromethyl)pyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H23F3N6O2
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0850936
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2-methoxyethyl)acetamide
Show/Hide
|
C25H28N6O4
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0864426
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-1-(pyrrolidin-1-yl)ethanone
Show/Hide
|
C26H28N6O3
|
2
|
| 1 |
IC50 = 1819.7 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649800
|
(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(3-(pyrrolidin-1-yl)propyl)amino)phenyl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C31H37N7O2
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667776
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-methoxyethyl)-2-methylpropanamide
Show/Hide
|
C30H36N6O4
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672899
|
N-(3,5-dimethoxyphenyl)-N-(2-(3-methyl-1H-1,2,4-triazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H26N8O2
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0701312
|
4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)piperidin-4-ol
Show/Hide
|
C28H30N6O3
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0786937
|
N-(cyclopentylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H29N5O2
|
2
|
| 1 |
IC50 = 1862.09 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664656
|
4-((4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)methyl)piperidin-4-ol
Show/Hide
|
C29H34N6O3
|
2
|
| 1 |
IC50 = 1905.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664764
|
N1-(3,5-dimethoxyphenyl)-N1-(3-(5-ethyl-1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,2-trifluoroethyl)ethane-1,2-diamine
Show/Hide
|
C26H29F3N6O2
|
2
|
| 1 |
IC50 = 1905.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688466
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H25N5O2
|
2
|
| 1 |
IC50 = 1905.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0690292
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(3-(2-(methylsulfonyl)ethylamino)propyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H36N6O4S
|
2
|
| 1 |
IC50 = 1949.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0707219
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(3-methoxypyridin-2-yl)acetamide
Show/Hide
|
C28H27N7O4
|
2
|
| 1 |
IC50 = 1949.84 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0767025
|
N-(2-aminoethyl)-2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetamide hydrochloride
Show/Hide
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C24H28ClN7O3
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2
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| 1 |
IC50 = 1949.84 nM
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| 2 |
IC50 > 10000 nM
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CP0667772
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N-(3,5-dimethoxyphenyl)-N-((6-(dimethylamino)pyridin-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C28H29N7O2
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2
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| 1 |
IC50 = 1995.26 nM
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| 2 |
IC50 > 10000 nM
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CP0667775
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1-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-2-methylpropan-2-ol
Show/Hide
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C27H31N5O3
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2
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| 1 |
IC50 = 1995.26 nM
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| 2 |
IC50 > 10000 nM
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CP0704647
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N1-(3-fluoro-5-methoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
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C21H21FN6O
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2
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| 1 |
IC50 = 1995.26 nM
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| 2 |
IC50 > 10000 nM
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CP0664657
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2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-hydroxyethyl)-2-methylpropanamide
Show/Hide
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C29H34N6O4
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2
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| 1 |
IC50 = 2041.74 nM
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| 2 |
IC50 > 10000 nM
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CP0664718
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2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-N-(2-(pyrrolidin-1-yl)ethyl)acetamide
Show/Hide
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C31H37N7O3
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2
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| 1 |
IC50 = 2041.74 nM
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| 2 |
IC50 > 10000 nM
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CP0704179
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N-(3-chlorobenzyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C27H24ClN5O2
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2
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| 1 |
IC50 = 2041.74 nM
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| 2 |
IC50 > 10000 nM
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CP0738547
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7-[N-(cyclopropylmethyl)-3,5-dimethoxy-anilino]-2-[1-[2-(dimethylsulfamoylamino)ethyl]pyrazol-4-yl]quinoxaline
Show/Hide
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C27H33N7O4S
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2
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| 1 |
IC50 = 2041.74 nM
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| 2 |
IC50 > 10000 nM
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CP0664785
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(S)-1-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)pyrrolidine-2-carboxylic acid hydrochloride
Show/Hide
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C27H31ClN6O4
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2
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| 1 |
IC50 = 2089.3 nM
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| 2 |
IC50 > 10000 nM
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CP0701278
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2-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(2-chloro-5-methoxyphenyl)amino)ethanol hydrochloride
Show/Hide
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C20H19Cl2N5O2
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2
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| 1 |
IC50 = 2089.3 nM
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| 2 |
IC50 > 10000 nM
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CP0418567
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3-[4-amino-7-[3-(hydroxymethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-5-yl]phenol
Show/Hide
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C17H18N4O2
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1
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| 1 |
IC50 = 2100 nM
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CP0664658
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N1-(cyclopropylmethyl)-N3-methyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)benzene-1,3-diamine
Show/Hide
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C23H24N6
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2
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| 1 |
IC50 = 2137.96 nM
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| 2 |
IC50 > 10000 nM
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CP0672834
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N-(2,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
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C27H33ClN6O2
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2
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| 1 |
IC50 = 2137.96 nM
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| 2 |
IC50 > 10000 nM
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CP0749415
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2-(3-((2-aminoethyl)(7-(1-methyl-1H-pyrazol-4-yl)quinoxalin-2-yl)amino)-5-fluorophenoxy)ethanol
Show/Hide
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C22H23FN6O2
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2
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| 1 |
IC50 = 2137.96 nM
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| 2 |
IC50 > 10000 nM
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CP0698827
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(E)-1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-one oxime
Show/Hide
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C25H28N6O3
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2
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| 1 |
IC50 = 2187.76 nM
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| 2 |
IC50 > 10000 nM
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CP0701305
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(Z)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyridin-2-yl)allyl)quinoxalin-6-amine
Show/Hide
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C29H28N6O2
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2
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| 1 |
IC50 = 2187.76 nM
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| 2 |
IC50 > 10000 nM
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CP0672891
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(E)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(4-methylpyridin-2-yl)allyl)quinoxalin-6-amine
Show/Hide
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C29H28N6O2
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2
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| 1 |
IC50 = 2238.72 nM
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| 2 |
IC50 > 10000 nM
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CP0673350
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2-((3-methoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
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C21H21N5O2
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2
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| 1 |
IC50 = 2238.72 nM
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| 2 |
IC50 > 10000 nM
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CP0664720
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N-(3-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((3-methylisoxazol-5-yl)methyl)quinoxalin-6-amine
Show/Hide
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C24H22N6O2
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2
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| 1 |
IC50 = 2290.87 nM
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| 2 |
IC50 > 10000 nM
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CP0688449
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N-(3,5-dimethoxyphenyl)-N-(dimethylsulfamoyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C22H24N6O4S
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2
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| 1 |
IC50 = 2290.87 nM
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| 2 |
IC50 > 10000 nM
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CP0744800
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N-(2-(1H-pyrazol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C25H25N7O2
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2
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| 1 |
IC50 = 2290.87 nM
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| 2 |
IC50 > 10000 nM
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CP0803486
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2-((3,5-dimethoxyphenyl)(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
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C24H27N5O3
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2
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| 1 |
IC50 = 2290.87 nM
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| 2 |
IC50 > 10000 nM
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CP0707213
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2-(3-((2-aminoethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenoxy)ethanol hydrochloride
Show/Hide
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C23H27ClN6O3
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2
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| 1 |
IC50 = 2344.23 nM
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| 2 |
IC50 > 10000 nM
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CP0664748
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N1-(3,5-dichlorophenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
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C23H24Cl2N6
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2
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| 1 |
IC50 = 2398.83 nM
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| 2 |
IC50 = 5754.4 nM
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CP0698823
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2-((2,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol hydrochloride
Show/Hide
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C22H24ClN5O3
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2
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| 1 |
IC50 = 2398.83 nM
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| 2 |
IC50 > 10000 nM
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CP0720052
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(3,3,3-trifluoropropyl)ethane-1,2-diamine
Show/Hide
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C25H27F3N6O2
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2
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| 1 |
IC50 = 2454.71 nM
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| 2 |
IC50 > 10000 nM
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CP0673321
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)quinoxalin-6-amine
Show/Hide
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C28H31F3N6O2
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2
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| 1 |
IC50 = 2511.89 nM
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| 2 |
IC50 > 10000 nM
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CP0649787
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3-(1-(3-aminopropyl)-1H-pyrazol-4-yl)-N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine
Show/Hide
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C26H30N6O2
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2
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| 1 |
IC50 = 2570.4 nM
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| 2 |
IC50 > 10000 nM
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CP0692302
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2-((3,5-dimethoxycyclohexa-2,4-dienyl)(3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
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C23H24F3N5O3
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2
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| 1 |
IC50 = 2570.4 nM
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| 2 |
IC50 > 10000 nM
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CP0688439
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(E)-N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)allyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C29H28N6O3
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2
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| 1 |
IC50 = 2630.27 nM
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| 2 |
IC50 > 10000 nM
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CP0692282
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyridin-3-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
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C28H24N6O2
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2
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| 1 |
IC50 = 2630.27 nM
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| 2 |
IC50 > 10000 nM
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CP0686567
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3-((3,5-dimethoxyphenyl)(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propan-1-ol
Show/Hide
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C25H29N5O3
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2
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| 1 |
IC50 = 2691.53 nM
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| 2 |
IC50 > 10000 nM
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CP0831841
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-fluoroethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C25H26FN5O2
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2
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| 1 |
IC50 = 2754.23 nM
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| 2 |
IC50 > 10000 nM
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CP0866314
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N1-(3,5-dimethoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)ethane-1,2-diamine
Show/Hide
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C31H41N7O2
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2
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| 1 |
IC50 = 2754.23 nM
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| 2 |
IC50 > 10000 nM
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CP0692277
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N-(3,5-dimethoxyphenyl)-N-(3-(3-methoxyphenyl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C30H27N5O3
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2
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| 1 |
IC50 = 2818.38 nM
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| 2 |
IC50 = 8317.64 nM
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CP0701262
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)acetamide
Show/Hide
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C22H22N6O3
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2
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| 1 |
IC50 = 2818.38 nM
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| 2 |
IC50 > 10000 nM
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CP0692286
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((2-(pyridin-4-yl)cyclopropyl)methyl)quinoxalin-6-amine
Show/Hide
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C29H28N6O2
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2
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| 1 |
IC50 = 2884.03 nM
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| 2 |
IC50 > 10000 nM
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CP0701282
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2-(5-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1,3,4-oxadiazol-2-ylamino)ethanol
Show/Hide
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C25H26N8O4
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2
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| 1 |
IC50 = 3019.95 nM
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| 2 |
IC50 > 10000 nM
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CP0806540
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N-(2-(4H-1,2,4-triazol-4-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H24N8O2
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2
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| 1 |
IC50 = 3090.3 nM
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| 2 |
IC50 > 10000 nM
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CP0388615
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3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-(1,3-thiazol-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
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C23H26N6O3S
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1
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| 1 |
IC50 = 3100 nM
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CP0673347
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N1-(3-fluoro-5-methoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C24H24F4N6O
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2
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| 1 |
IC50 = 3162.28 nM
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| 2 |
IC50 > 10000 nM
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CP0698818
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N-benzyl-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C27H25N5O2
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2
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| 1 |
IC50 = 3162.28 nM
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| 2 |
IC50 > 10000 nM
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CP0664715
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-isobutyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C27H31N5O2
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2
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| 1 |
IC50 = 3235.94 nM
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| 2 |
IC50 > 10000 nM
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CP0667766
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N-(2-(1H-pyrrol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
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C26H27ClN6O2
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2
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| 1 |
IC50 = 3235.94 nM
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| 2 |
IC50 > 10000 nM
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CP0707091
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N-(2-(1H-pyrrol-1-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H26N6O2
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2
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| 1 |
IC50 = 3235.94 nM
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| 2 |
IC50 > 10000 nM
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CP0848581
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N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-((trimethylsilyl)methyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H33N5O2Si
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2
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| 1 |
IC50 = 3235.94 nM
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| 2 |
IC50 > 10000 nM
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CP0690291
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N-(2-methoxyethyl)-N-(3-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C22H23N5O2
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2
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| 1 |
IC50 = 3630.78 nM
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| 2 |
IC50 > 10000 nM
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CP0692228
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N1-(3-ethoxy-5-fluorophenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C22H23FN6O
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2
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| 1 |
IC50 = 3630.78 nM
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| 2 |
IC50 > 10000 nM
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CP0726485
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2-(4-(7-((cyclopropylmethyl)(phenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C23H23N5O
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2
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| 1 |
IC50 = 3630.78 nM
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| 2 |
IC50 > 10000 nM
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CP0744807
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N-(3,5-dimethoxyphenyl)-N-(2-(5-methyl-1H-pyrazol-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N7O2
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2
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| 1 |
IC50 = 3630.78 nM
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| 2 |
IC50 > 10000 nM
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CP0692218
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N1-(2,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine
Show/Hide
|
C25H30N6O2
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2
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| 1 |
IC50 = 3715.35 nM
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| 2 |
IC50 > 10000 nM
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CP0672898
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(2-(2,4,4-trimethyl-4,5-dihydro-1H-imidazol-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C28H33N7O2
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2
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| 1 |
IC50 = 3981.07 nM
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| 2 |
IC50 > 10000 nM
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CP0690287
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N-(3-(5-aminopyrazin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H24N8O2
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2
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| 1 |
IC50 = 3981.07 nM
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| 2 |
IC50 > 10000 nM
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CP0667770
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(1-methyl-1H-pyrazol-4-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C27H25N7O2
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2
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| 1 |
IC50 = 4073.8 nM
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| 2 |
IC50 > 10000 nM
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CP0717321
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N-allyl-N-(3-fluoro-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C22H20FN5O
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2
|
| 1 |
IC50 = 4073.8 nM
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| 2 |
IC50 > 10000 nM
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CP0707090
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N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(5-methylpyridin-2-yl)prop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O2
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2
|
| 1 |
IC50 = 4168.69 nM
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| 2 |
IC50 > 10000 nM
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CP0700930
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3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)propanoic acid hydrochloride
Show/Hide
|
C23H24ClN5O4
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2
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| 1 |
IC50 = 4466.84 nM
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| 2 |
IC50 > 10000 nM
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CP0717315
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N-((1,4-dibenzylpiperazin-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C39H41N7O2
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2
|
| 1 |
IC50 = 4677.35 nM
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| 2 |
IC50 > 10000 nM
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CP0657869
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2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-isopropylpropanamide
Show/Hide
|
C26H30N6O3
|
2
|
| 1 |
IC50 = 4786.3 nM
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| 2 |
IC50 > 10000 nM
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CP0692292
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N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2,5-dimethoxyphenyl)-N2-isopropylethane-1,2-diamine
Show/Hide
|
C24H28N6O2
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704629
|
2-(4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)-2-methyl-1-(piperazin-1-yl)propan-1-one
Show/Hide
|
C31H37N7O3
|
2
|
| 1 |
IC50 = 4897.79 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692260
|
N-(3,5-dimethoxyphenyl)-N-((1-ethyl-1H-imidazol-2-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N7O2
|
2
|
| 1 |
IC50 = 5248.07 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0667767
|
(R/S)-3-((2,3-dihydroxypropyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxy-N-methylbenzamide
Show/Hide
|
C24H26N6O4
|
2
|
| 1 |
IC50 = 5370.32 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0683614
|
N1-(3-(1H-pyrazol-4-yl)quinoxalin-6-yl)-N1-(2,5-dimethoxyphenyl)ethane-1,2-diamine hydrochloride
Show/Hide
|
C21H23ClN6O2
|
2
|
| 1 |
IC50 = 5495.41 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0851636
|
2-(4-(7-((3-(2-hydroxyethoxy)-5-methoxyphenyl)(2-hydroxyethyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C24H27N5O5
|
2
|
| 1 |
IC50 = 5623.41 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664742
|
(3-((3-hydroxypropyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenyl)(pyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C27H31ClN6O3
|
2
|
| 1 |
IC50 = 5888.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0704126
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-phenylprop-2-ynyl)quinoxalin-6-amine
Show/Hide
|
C29H25N5O2
|
2
|
| 1 |
IC50 = 5888.44 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649783
|
1-(4-((3-aminopropyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2,6-dimethoxyphenyl)-2,2,2-trifluoroethanol
Show/Hide
|
C25H27F3N6O3
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0664766
|
tert-butyl 4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)piperidine-1-carboxylate
Show/Hide
|
C33H38N6O4
|
2
|
| 1 |
IC50 = 6165.95 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672900
|
N-(3-(3-aminophenyl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O2
|
2
|
| 1 |
IC50 = 6309.57 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0751770
|
3-(1-(2-aminoethyl)-1H-pyrazol-4-yl)-N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine
Show/Hide
|
C25H28N6O2
|
2
|
| 1 |
IC50 = 6309.57 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0811738
|
N-(3,5-dimethoxyphenyl)-N-(3-(1-methyl-1H-imidazol-5-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H25N7O2
|
2
|
| 1 |
IC50 = 6309.57 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702433
|
N-(2-chlorobenzyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H24ClN5O2
|
2
|
| 1 |
IC50 = 6456.54 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0692460
|
N-((5-chlorothiophen-2-yl)methyl)-3-(1-((5-chlorothiophen-2-yl)methyl)-1H-pyrazol-4-yl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amine
Show/Hide
|
C29H23Cl2N5O2S2
|
2
|
| 1 |
IC50 = 6760.83 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0700925
|
N-(3-chloro-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H22ClN5O
|
2
|
| 1 |
IC50 = 6918.31 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0673323
|
2-(3-methoxy-5-((3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)(2-(methylamino)ethyl)amino)phenoxy)ethanol hydrochloride
Show/Hide
|
C24H29ClN6O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0688442
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-(methoxymethyl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H27N5O2
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0773259
|
N-(3,5-dimethoxyphenyl)-N-(3-(6-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
2
|
| 1 |
IC50 = 7079.46 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0748524
|
N-(3,5-dimethoxyphenyl)-N-(4-(4-methoxypyrimidin-2-yl)-2-methylbut-3-yn-2-yl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C30H29N7O3
|
2
|
| 1 |
IC50 = 7244.36 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717813
|
N-(3-(4-aminophenyl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O2
|
2
|
| 1 |
IC50 = 7585.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0757780
|
4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)benzonitrile
Show/Hide
|
C30H24N6O2
|
2
|
| 1 |
IC50 = 7585.78 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0702094
|
N-(3,5-dimethoxyphenyl)-N-(3-(2,6-dimethoxypyrimidin-4-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H27N7O4
|
2
|
| 1 |
IC50 = 7943.28 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0726479
|
tert-butyl 4-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)-4-hydroxypiperidine-1-carboxylate, oxalate salt
Show/Hide
|
C35H40N6O9
|
2
|
| 1 |
IC50 = 8317.64 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649790
|
2-(2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl)isoindoline-1,3-dione
Show/Hide
|
C30H26N6O4
|
2
|
| 1 |
IC50 = 8912.51 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0717814
|
2-(3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)prop-1-ynyl)benzonitrile
Show/Hide
|
C30H24N6O2
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0786936
|
N-(cyclopropylmethyl)-N-(3-((dimethylamino)methyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H30N6O
|
2
|
| 1 |
IC50 = 9120.11 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0672829
|
N-(3-cyclohexylprop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H31N5O2
|
2
|
| 1 |
IC50 = 9549.93 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0649782
|
N-(cyclopropylmethyl)-N-(3-((ethyl(methyl)amino)methyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H32N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649785
|
1-(1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-yloxy)-3-methylbutan-2-ol
Show/Hide
|
C30H39N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649795
|
N-(3-(aminomethyl)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C24H27ClN6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0649814
|
N-(3-(1,3-dioxolan-2-yl)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H27N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667771
|
2-((3,5-dimethoxycyclohexa-2,4-dienyl)(3-(1-methyl-3,5-bis(trifluoromethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
Show/Hide
|
C24H23F6N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672833
|
3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxybenzonitrile
Show/Hide
|
C24H22N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672904
|
2-(4-(7-((cyclopropylmethyl)(3-fluoro-5-methoxyphenyl)amino)quinoxalin-2-yl)-1H-pyrazol-1-yl)ethanol
Show/Hide
|
C24H24FN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672908
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-vinylphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C25H26ClN5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688426
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(4-phenylbut-3-ynyl)quinoxalin-6-amine
Show/Hide
|
C30H27N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688464
|
N-(3-(5H-pyrrolo[2,3-b]pyrazin-2-yl)prop-2-ynyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H24N8O2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0701252
|
(3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-5-methoxyphenyl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C28H30N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0701254
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(((1S,2S)-2-(pyridin-2-yl)cyclopropyl)methyl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0702102
|
N-(4-chlorobenzyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H24ClN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0702435
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-(2-methoxyethyl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30ClN5O2
|
2
|
| 1 |
IC50 > 10000 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0704131
|
1-(1-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-3-methylbutan-2-yloxy)-3-methylbutan-2-ol hydrochloride
Show/Hide
|
C30H40ClN5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704177
|
N-(2-chloro-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30Cl2N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0707222
|
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(methylsulfonyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H25N5O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0708029
|
N-(3,5-dimethoxyphenyl)-N-(3-(1-methyl-1H-imidazol-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C27H25N7O2
|
2
|
| 1 |
IC50 >= 10000 nM
|
|
|
| 2 |
IC50 < 120.23 nM
|
|
|
|
CP0719594
|
4-(7-((cyclopropylmethyl)(3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)-N,N-dimethyl-1H-pyrazole-1-sulfonamide
Show/Hide
|
C25H28N6O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0726426
|
N-(3,5-dimethoxyphenyl)-3-(1-isobutyl-1H-pyrazol-4-yl)-N-(2-(5-methyl-1H-1,2,4-triazol-1-yl)ethyl)quinoxalin-6-amine
Show/Hide
|
C28H32N8O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0726447
|
N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(trifluoromethoxy)phenyl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C23H21ClF3N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0749392
|
N-(2-(1H-tetrazol-5-yl)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H23N9O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0773301
|
N-(3,5-dimethoxyphenyl)-N-((1-(4-methoxypyrimidin-2-yl)piperidin-4-yl)methyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C31H34N8O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0805838
|
N-((5-chlorothiophen-2-yl)methyl)-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H20ClN5O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0837741
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-(2-(methylamino)ethoxy)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H30N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0657883
|
N1-(3,5-dichlorophenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine
Show/Hide
|
C23H21Cl2F3N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0667773
|
N-(cyclopropylmethyl)-N-(3-isopropoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H27N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0672897
|
N-(cyclopropylmethyl)-N-(3-methoxy-5-(trifluoromethyl)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C24H22F3N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0675665
|
N-(cyclopropylmethyl)-N-(3-(ethoxymethyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0675666
|
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethylphosphonic acid hydrobromide
Show/Hide
|
C22H25BrN5O5P
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688430
|
N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-phenylquinoxalin-6-amine
Show/Hide
|
C22H21N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0688431
|
N-(3,5-dimethoxyphenyl)-N-(3-(5-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C29H26N6O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0690294
|
N-(cyclopropylmethyl)-N-(3-isopropoxy-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
|
C26H30ClN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0690540
|
ethyl 2-(4-(((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetate
Show/Hide
|
C27H28N8O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0692303
|
N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(((1R,2R)-2-(pyridin-2-yl)cyclopropyl)methyl)quinoxalin-6-amine
Show/Hide
|
C29H28N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0698817
|
N-(3-(2-aminoethoxy)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C25H28N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0701261
|
3-((cyclopropylmethyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)benzonitrile
Show/Hide
|
C23H20N6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0704156
|
N-(cyclopropylmethyl)-N-(3-(difluoromethoxy)phenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
|
C23H21F2N5O
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1
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| 1 |
IC50 > 10000 nM
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CP0704631
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N-(3-(cyclopropylmethoxy)-5-methoxyphenyl)-N-(cyclopropylmethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
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C27H30ClN5O2
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0704713
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N1-(3,4-difluoro-5-methoxyphenyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)-N3-(2,2,2-trifluoroethyl)propane-1,3-diamine hydrochloride
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C24H24ClF5N6O
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0726451
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N-(cyclopropylmethyl)-N-(2,3-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C24H25N5O2
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0744812
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N-(cyclopropylmethyl)-N-phenyl-3-(1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
Show/Hide
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C21H20ClN5
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0751768
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N1-(cyclopropylmethyl)-N3,N3-dimethyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)benzene-1,3-diamine hydrochloride
Show/Hide
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C24H27ClN6
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0776290
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N-(cyclopropylmethyl)-N-(3-fluoro-5-methoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine
Show/Hide
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C22H20FN5O
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0803485
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N-(3-((diethylamino)methyl)-5-methoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-(3-(pyrrolidin-1-yl)propyl)quinoxalin-6-amine
Show/Hide
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C31H41N7O
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1
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| 1 |
IC50 > 10000 nM
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|
|
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CP0138866
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1-[4-[3-[4-amino-5-(2-fluoro-5-hydroxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
Show/Hide
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C22H25FN6O2
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1
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| 1 |
IC50 > 11000 nM
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|
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CP0388616
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3-(3,4-dimethoxyphenyl)-5-(1-methylpiperidin-4-yl)oxy-6-phenylpyrazolo[1,5-a]pyrimidin-7-amine
Show/Hide
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C26H29N5O3
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1
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| 1 |
IC50 > 5600 nM
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