Brief Information of the Compound and Protein
Compound Name
N-(3-((3-(1H-pyrazol-4-yl)quinoxalin-6-yl)(3,5-dimethoxyphenyl)amino)propyl)-2,2,2-trifluoroacetamide, 2,2,2-trifluoroacetate salt
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PubChem ID
CID: 134157956
Canonical SMILES
COc1cc(OC)cc(N(CCCNC(=O)C(F)(F)F)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1.O=C(O)C(F)(F)F
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Compound Formula C26H24F6N6O5
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 30.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 9332.54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.7586 nM