Brief Information of the Compound and Protein
Compound Name
2-(3,5-dimethoxy-N-[7-[1-(trideuteriomethyl)pyrazol-4-yl]quinoxalin-2-yl]anilino)ethanol
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PubChem ID
CID: 134154678
Canonical SMILES
[2H]C([2H])([2H])n1cc(-c2ccc3ncc(N(CCO)c4cc(OC)cc(OC)c4)nc3c2)cn1
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Compound Formula C22H23N5O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 281.84 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.818 nM