Brief Information of the Compound and Protein
Compound Name
N-(2,6-difluoro-3,5-dimethoxyphenyl)-N-(3-(3-methoxypyridin-2-yl)prop-2-ynyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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PubChem ID
CID: 89447476
Canonical SMILES
COc1cccnc1C#CCN(c1ccc2ncc(-c3cnn(C)c3)nc2c1)c1c(F)c(OC)cc(OC)c1F
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Compound Formula C29H24F2N6O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 0.6026 nM
   TI
   LI
   LO
   TS
2
IC50 = 7244.36 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.738 nM