Brief Information of the Compound and Protein
Compound Name
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-6-amine
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PubChem ID
CID: 68209368
Canonical SMILES
COc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C5CCNCC5)c4)nc3c2)c1
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Compound Formula C28H32N6O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 1584.89 nM
   TI
   LI
   LO
   TS
2
IC50 = 6456.54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.023 nM