Brief Information of the Compound and Protein
Compound Name
2-((3,5-dimethoxycyclohexa-2,4-dienyl)(3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
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PubChem ID
CID: 134142040
Canonical SMILES
COC1=CC(N(CCO)c2ccc3ncc(-c4cn(C)nc4C(F)(F)F)nc3c2)CC(OC)=C1
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Compound Formula C23H24F3N5O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 2570.4 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 64.57 nM