Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-1-((S)-3-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-2-hydroxypropyl)pyrrolidine-3-carbonitrile hydrochloride
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 PubChem ID
CID: 134151339
Canonical SMILES
COc1cc(OC)cc(N(C[C@@H](O)CN2CC[C@H](C#N)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1.Cl
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Compound Formula C28H32ClN7O3
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 38.02 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.129 nM