Brief Information of the Compound and Protein
Compound Name
7-[N-[2-(dimethylsulfamoylamino)ethyl]-3,5-dimethoxy-anilino]-2-(1-methylpyrazol-4-yl)quinoxaline
    Show/Hide
PubChem ID
CID: 68208755
Canonical SMILES
COc1cc(OC)cc(N(CCNS(=O)(=O)N(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
    Show/Hide
Compound Formula C24H29N7O4S
Compound Structure
Protein Name
Fibroblast growth factor receptor 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P11362
Gene Name
FGFR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 18.2 nM
   TI
   LI
   LO
   TS
2
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5623 nM