| Compound ID |
Compound Name |
Compound Formula |
|
CP0544962
|
N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-2-[(1,3-dioxoisoindol-2-yl)methyl]-6-fluoro-3-hydroxybenzamide
Show/Hide
|
C33H25FN6O5S
|
3
|
| 1 |
EC50 = 5.8 nM
|
|
|
| 2 |
IC50 = 1.2 nM
|
|
|
| 3 |
IC50 = 32 nM
|
|
|
|
CP0078880
|
4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide
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|
C30H29ClN6O3
|
2
|
| 1 |
IC50 = 0.02 nM
|
|
|
| 2 |
IC50 = 0.8 nM
|
|
|
|
CP0033646
|
AZD-9291
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|
C28H33N7O2
|
14
|
| 1 |
IC50 = 0.02 nM
|
|
|
| 2 |
IC50 = 0.06 nM
|
|
|
| 3 |
IC50 = 0.2 nM
|
|
|
| 4 |
IC50 = 1.5 nM
|
|
|
| 5 |
IC50 = 2 nM
|
|
|
| 6 |
IC50 = 17 nM
|
|
|
| 7 |
IC50 = 19.04 nM
|
|
|
| 8 |
IC50 = 20.8 nM
|
|
|
| 9 |
IC50 = 90 nM
|
|
|
| 10 |
IC50 = 278 nM
|
|
|
| 11 |
IC50 = 495.7 nM
|
|
|
| 12 |
IC50 = 567.5 nM
|
|
|
| 13 |
IC50 = 1230 nM
|
|
|
| 14 |
IC50 > 1000 nM
|
|
|
|
CP0007142
|
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
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|
C29H26ClFN4O4S
|
3
|
| 1 |
IC50 = 0.06 nM
|
|
|
| 2 |
IC50 = 0.2 nM
|
|
|
| 3 |
IC50 = 24 nM
|
|
|
|
CP0500354
|
N-[5-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Show/Hide
|
C31H27N7O3
|
3
|
| 1 |
IC50 = 0.07 nM
|
|
|
| 2 |
IC50 = 0.1 nM
|
|
|
| 3 |
IC50 = 6 nM
|
|
|
|
CP0491530
|
N-[3-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C27H21ClN6O2
|
3
|
| 1 |
IC50 = 0.08 nM
|
|
|
| 2 |
IC50 = 0.1 nM
|
|
|
| 3 |
IC50 = 3.9 nM
|
|
|
|
CP0486641
|
N-[5-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]prop-2-enamide
Show/Hide
|
C31H30ClN7O3
|
3
|
| 1 |
IC50 = 0.09 nM
|
|
|
| 2 |
IC50 = 0.1 nM
|
|
|
| 3 |
IC50 = 2 nM
|
|
|
|
CP0571686
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C26H34FN7O3S
|
2
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 1050 nM
|
|
|
|
CP0059062
|
N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Show/Hide
|
C25H27ClN6O3
|
6
|
| 1 |
IC50 = 0.19 nM
|
|
|
| 2 |
IC50 = 0.42 nM
|
|
|
| 3 |
IC50 < 1 nM
|
|
|
| 4 |
IC50 = 10 nM
|
|
|
| 5 |
IC50 = 16 nM
|
|
|
| 6 |
IC50 = 2050 nM
|
|
|
|
CP0513510
|
N-[3-[4-[4-[(1,3-dioxoisoindol-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C30H22N6O3
|
3
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
| 3 |
IC50 = 33 nM
|
|
|
|
CP0568877
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C27H36FN7O3S
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 270 nM
|
|
|
|
CP0571685
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C27H35FN6O3S
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 385 nM
|
|
|
|
CP0325284
|
N-[3-[[4-[5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]pyridin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide
Show/Hide
|
C25H22FN5O2S
|
3
|
| 1 |
IC50 = 0.26 nM
|
|
|
| 2 |
IC50 = 6.5 nM
|
|
|
| 3 |
IC50 = 130 nM
|
|
|
|
CP0004106
|
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
Show/Hide
|
C28H26N4O3
|
2
|
| 1 |
IC50 = 0.29 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
|
CP0053637
|
(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Show/Hide
|
C24H25ClFN5O3
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 15.4 nM
|
|
|
|
CP0543294
|
(3S,4R)-3-fluoro-1-[4-[[8-[(2R,3S)-3-hydroxy-2-methylazetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C25H32FN7O2
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 4503 nM
|
|
|
|
CP0546825
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C28H37FN6O3S
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 505 nM
|
|
|
|
CP0546832
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R)-2-methylazetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C25H32FN7O
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 7289 nM
|
|
|
|
CP0545094
|
(3S,4R)-3-fluoro-4-methyl-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C28H37FN6O3S
|
2
|
| 1 |
IC50 = 0.4 nM
|
|
|
| 2 |
IC50 = 1089 nM
|
|
|
|
CP0564476
|
BLU-945
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|
C28H37FN6O3S
|
6
|
| 1 |
IC50 = 0.4 nM
|
|
|
| 2 |
IC50 = 0.7 nM
|
|
|
| 3 |
IC50 = 0.8 nM
|
|
|
| 4 |
IC50 = 7.4 nM
|
|
|
| 5 |
IC50 = 25 nM
|
|
|
| 6 |
IC50 = 683 nM
|
|
|
|
CP0546833
|
(3S,4R)-3-ethyl-3-fluoro-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C29H39FN6O3S
|
2
|
| 1 |
IC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 761 nM
|
|
|
|
CP0568875
|
(3S,4R)-3-fluoro-1-[4-[[8-[(2R,3S)-3-hydroxy-2-methylazetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C26H33FN6O2
|
2
|
| 1 |
IC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 2222 nM
|
|
|
|
CP0534286
|
1-[4-[(4-benzamidopyrimidin-2-yl)amino]-5-methoxy-2-(prop-2-enoylamino)phenyl]piperidine-4-carboxamide
Show/Hide
|
C27H29N7O4
|
2
|
| 1 |
IC50 = 0.5872 nM
|
|
|
| 2 |
IC50 = 180.6 nM
|
|
|
|
CP0568871
|
(3R,4R)-5,5-difluoro-4-methoxy-1-[4-[[8-[(2R,3S)-2-methyl-3-(methylsulfonylmethyl)azetidin-1-yl]-5-propan-2-ylisoquinolin-3-yl]amino]pyrimidin-2-yl]piperidin-3-ol
Show/Hide
|
C28H36F2N6O4S
|
2
|
| 1 |
IC50 = 0.7 nM
|
|
|
| 2 |
IC50 = 810 nM
|
|
|
|
CP0404834
|
N-[3-[[5-chloro-2-[4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C24H25ClN6O2
|
2
|
| 1 |
IC50 = 0.71 nM
|
|
|
| 2 |
IC50 = 448.7 nM
|
|
|
|
CP0573155
|
1-[6-[[2-[(3S,4R)-3-fluoro-4-hydroxy-3-methylpiperidin-1-yl]pyrimidin-4-yl]amino]-4-propan-2-yl-2,7-naphthyridin-1-yl]-N,N-dimethylazetidine-3-carboxamide
Show/Hide
|
C27H35FN8O2
|
2
|
| 1 |
IC50 = 0.9 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0036082
|
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Show/Hide
|
C22H24ClFN4O3
|
10
|
| 1 |
IC50 < 1 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
| 3 |
IC50 = 4 nM
|
|
|
| 4 |
IC50 = 15.5 nM
|
|
|
| 5 |
IC50 = 20 nM
|
|
|
| 6 |
IC50 = 33 nM
|
|
|
| 7 |
IC50 = 390 nM
|
|
|
| 8 |
IC50 = 823.3 nM
|
|
|
| 9 |
IC50 = 3170 nM
|
|
|
| 10 |
IC50 = 4990 nM
|
|
|
|
CP0385834
|
N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-(4-methylpiperazin-1-yl)phenyl]prop-2-enamide
Show/Hide
|
C28H31N7O2
|
5
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 < 1 nM
|
|
|
| 3 |
IC50 = 2 nM
|
|
|
| 4 |
Ki = 1.46 nM
|
|
|
| 5 |
Ki = 1.58 nM
|
|
|
|
CP0116990
|
AP-26113
Show/Hide
|
C29H39ClN7O2P
|
3
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
| 3 |
IC50 = 130 nM
|
|
|
|
CP0569543
|
1-[6-[[2-[(3S,4R)-3-fluoro-4-hydroxy-3-methylpiperidin-1-yl]pyrimidin-4-yl]amino]-4-propan-2-yl-2,7-naphthyridin-1-yl]-N-methylazetidine-3-carboxamide
Show/Hide
|
C26H33FN8O2
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0443808
|
N-[4-(2-fluoro-3-methylanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C18H15FN4O
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0568878
|
(3S,4R)-3-fluoro-1-[4-[[8-[(2R,3S)-3-hydroxy-2-methylazetidin-1-yl]-5-propan-2-yl-2,6-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C25H32FN7O2
|
2
|
| 1 |
IC50 = 1.8 nM
|
|
|
| 2 |
IC50 = 4194 nM
|
|
|
|
CP0065286
|
AVL-301
Show/Hide
|
C27H28F3N7O3
|
8
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
| 3 |
IC50 = 20 nM
|
|
|
| 4 |
IC50 = 21.5 nM
|
|
|
| 5 |
IC50 = 460 nM
|
|
|
| 6 |
IC50 = 500 nM
|
|
|
| 7 |
Ki = 1.65 nM
|
|
|
| 8 |
Ki = 1.75 nM
|
|
|
|
CP0374475
|
(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C19H18ClFN6O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0432954
|
N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C18H16ClFN4O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0432975
|
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-[di(propan-2-yl)amino]but-2-enamide
Show/Hide
|
C25H29ClFN5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0642885
|
N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide dihydrochloride
Show/Hide
|
C24H27Cl3FN5O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0419521
|
N-[5-methyl-1-(1-prop-2-enoylazepan-3-yl)benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
|
2
|
| 1 |
IC50 < 2 nM
|
|
|
| 2 |
IC50 = 830 nM
|
|
|
|
CP0569341
|
2-[(1,3-dioxoisoindol-2-yl)methyl]-6-fluoro-3-hydroxy-N-[3-[5-[2-[2-methoxy-5-(prop-2-enoylamino)anilino]pyridin-4-yl]-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]benzamide
Show/Hide
|
C41H32FN7O6S
|
3
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 4.9 nM
|
|
|
| 3 |
IC50 = 47 nM
|
|
|
|
CP0326484
|
N-[4-(4-bromo-2-fluoroanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C17H12BrFN4O
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0568873
|
(3S,4R)-1-[4-[[8-(azetidin-1-yl)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-fluoro-3-methylpiperidin-4-ol
Show/Hide
|
C24H30FN7O
|
2
|
| 1 |
IC50 = 2.1 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0037987
|
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Show/Hide
|
C22H23N3O4
|
8
|
| 1 |
IC50 = 2.17 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
| 3 |
IC50 = 30 nM
|
|
|
| 4 |
IC50 = 32 nM
|
|
|
| 5 |
IC50 = 60 nM
|
|
|
| 6 |
IC50 = 80 nM
|
|
|
| 7 |
IC50 = 160 nM
|
|
|
| 8 |
IC50 = 340 nM
|
|
|
|
CP0545095
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2R)-2-methylazetidin-1-yl]-5-propan-2-yl-2,6-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C25H32FN7O
|
2
|
| 1 |
IC50 = 2.2 nM
|
|
|
| 2 |
IC50 = 3420 nM
|
|
|
|
CP0459384
|
N-[2-[4-(dimethylamino)-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]benzamide
Show/Hide
|
C23H24N6O3
|
2
|
| 1 |
IC50 = 2.213 nM
|
|
|
| 2 |
IC50 = 125.1 nM
|
|
|
|
CP0546496
|
N-(3-bromo-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H11BrFN3O2
|
1
|
| 1 |
IC50 = 2.49 nM
|
|
|
|
CP0510166
|
N-[3-[[5-chloro-2-[4-(imidazol-1-ylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C23H20ClN7O
|
2
|
| 1 |
IC50 = 3.3 nM
|
|
|
| 2 |
IC50 = 1000 nM
|
|
|
|
CP0543295
|
(3S,4R)-3-fluoro-1-[4-[[8-(3-methoxyazetidin-1-yl)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C25H32FN7O2
|
2
|
| 1 |
IC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0567944
|
(3S,4R)-3-fluoro-1-[4-[[8-(3-hydroxyazetidin-1-yl)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C24H30FN7O2
|
2
|
| 1 |
IC50 = 3.6 nM
|
|
|
| 2 |
IC50 = 5521 nM
|
|
|
|
CP0561099
|
N-(3-chloro-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H11ClFN3O2
|
1
|
| 1 |
IC50 = 3.91 nM
|
|
|
|
CP0396216
|
N-[5-methyl-1-[3-(prop-2-enoylamino)phenyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H19F3N4O2
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0477918
|
N-[5-methyl-1-[(1R,3S)-3-(prop-2-enoylamino)cyclohexyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0495183
|
1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C25H30N6O2S
|
2
|
| 1 |
IC50 = 4.902 nM
|
|
|
| 2 |
IC50 = 359.33 nM
|
|
|
|
CP0568100
|
N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-2-fluoro-5-hydroxybenzamide
Show/Hide
|
C24H20FN5O3S
|
3
|
| 1 |
IC50 = 5.5 nM
|
|
|
| 2 |
IC50 = 6.2 nM
|
|
|
| 3 |
IC50 = 8 nM
|
|
|
|
CP0544267
|
1-[4-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C25H31N7O2
|
2
|
| 1 |
IC50 = 5.681 nM
|
|
|
| 2 |
IC50 = 36.08 nM
|
|
|
|
CP0198013
|
N-[4-[3-(2-chlorophenyl)-7-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]cyclohexyl]propanamide
Show/Hide
|
C33H41ClN8O2
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0153482
|
DACOMITINIB
Show/Hide
|
C24H25ClFN5O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0379990
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C30H31N7O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0406338
|
N-[4-(1H-indol-5-ylamino)-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C20H19N5O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0540561
|
N-(3-bromo-2,5-difluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H10BrF2N3O2
|
1
|
| 1 |
IC50 = 6.16 nM
|
|
|
|
CP0444249
|
N-(3-chlorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H12ClN3O2
|
1
|
| 1 |
IC50 = 6.41 nM
|
|
|
|
CP0495181
|
1-[4-[2-(4-morpholin-4-ylanilino)thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C24H27N5O3S
|
2
|
| 1 |
IC50 = 6.532 nM
|
|
|
| 2 |
IC50 = 197.03 nM
|
|
|
|
CP0431426
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C31H33N7O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0432689
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C32H33N7O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0458761
|
N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]cyclopentene-1-carboxamide
Show/Hide
|
C27H29ClFN5O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0545953
|
N-(5-bromo-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H11BrFN3O2
|
1
|
| 1 |
IC50 = 7.63 nM
|
|
|
|
CP0368845
|
2-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]ethanol
Show/Hide
|
C24H19FN4O
|
1
|
| 1 |
IC50 = 7.64 nM
|
|
|
|
CP0575022
|
1-[4-[[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxyanilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C26H35N7O3
|
2
|
| 1 |
IC50 = 7.696 nM
|
|
|
| 2 |
IC50 = 59.3 nM
|
|
|
|
CP0163868
|
4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime
Show/Hide
|
C20H18FN7O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0318731
|
5-(Dimethyl-hydrazonomethyl)-N-[1-(3-fluoro-benzyl)-1H-indazol-5-yl]-pyrimidine-4,6-diamine
Show/Hide
|
C21H21FN8
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0144546
|
3-(dimethylamino)-N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]propanamide
Show/Hide
|
C31H31N5O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0380016
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
Show/Hide
|
C33H35N7O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0568872
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-(methylamino)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C22H28FN7O
|
2
|
| 1 |
IC50 = 8.1 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0407941
|
N-[4-(3-bromoanilino)quinazolin-6-yl]furan-2-carboxamide
Show/Hide
|
C19H13BrN4O2
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0072497
|
4-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]butan-1-ol
Show/Hide
|
C26H23FN4O
|
1
|
| 1 |
IC50 = 8.83 nM
|
|
|
|
CP0407944
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-hydroxyphenyl)thiourea
Show/Hide
|
C21H16BrN5OS
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0454549
|
1-benzyl-3-[4-(3-bromoanilino)quinazolin-6-yl]urea
Show/Hide
|
C22H18BrN5O
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0281776
|
2-(4-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidin-5-yl)methyleneamino)piperazin-1-yl)ethanol
Show/Hide
|
C25H28FN9O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0445873
|
N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]propanamide
Show/Hide
|
C24H27ClFN5O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0564645
|
N-[3-[[5-fluoro-2-[4-(imidazol-1-ylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C23H20FN7O
|
2
|
| 1 |
IC50 = 9 nM
|
|
|
| 2 |
IC50 = 987 nM
|
|
|
|
CP0446694
|
N-[3-[[5-fluoro-2-[4-(2-imidazol-1-ylethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C24H22FN7O2
|
2
|
| 1 |
IC50 = 9.1 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0407945
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-methylthiourea
Show/Hide
|
C16H14BrN5S
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0507078
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-sulfamoylphenyl)thiourea
Show/Hide
|
C21H17BrN6O2S2
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0554089
|
1-[4-[5-chloro-2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C23H28ClFN6O2
|
2
|
| 1 |
IC50 = 9.6 nM
|
|
|
| 2 |
IC50 = 37.12 nM
|
|
|
|
CP0545480
|
1-[4-[2-(2-methoxy-4-morpholin-4-ylanilino)thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C25H29N5O4S
|
2
|
| 1 |
IC50 = 9.664 nM
|
|
|
| 2 |
IC50 = 246.21 nM
|
|
|
|
CP0379991
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C33H35N7O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0385108
|
N-[5-methyl-1-[3-[methyl(prop-2-enoyl)amino]phenyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C26H21F3N4O2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 22310 nM
|
|
|
|
CP0402978
|
4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-acetyloxy-9-(acetyloxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C38H59NO9
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
| 3 |
IC50 > 20000 nM
|
|
|
|
CP0444246
|
N-(3-bromo-2,6-difluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H10BrF2N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0407875
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-pyridin-3-ylthiourea
Show/Hide
|
C20H15BrN6S
|
1
|
| 1 |
IC50 = 10.2 nM
|
|
|
|
CP0545467
|
1-[4-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C25H29FN6O2S
|
2
|
| 1 |
IC50 = 10.32 nM
|
|
|
| 2 |
IC50 = 144.31 nM
|
|
|
|
CP0465699
|
N-(2-fluoro-3-iodophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H11FIN3O2
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0535799
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(2-morpholin-4-ylethyl)thiourea
Show/Hide
|
C21H23BrN6OS
|
1
|
| 1 |
IC50 = 10.7 nM
|
|
|
|
CP0571684
|
(3S,4R)-3-fluoro-1-[4-[[8-[3-(methoxymethyl)azetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]-3-methylpiperidin-4-ol
Show/Hide
|
C26H34FN7O2
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 10000 nM
|
|
|
|
CP0458413
|
1-benzyl-3-[4-(3-chloroanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C22H18ClN5S
|
1
|
| 1 |
IC50 = 11.4 nM
|
|
|
|
CP0647673
|
N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-(methyl-hydrazonomethyl)-pyrimidine-4,6-diamine
Show/Hide
|
C20H19FN8
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0374473
|
(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C21H20ClFN6O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0545481
|
1-[4-[5-chloro-2-[4-[[4-(hydroxymethyl)piperidin-1-yl]methyl]anilino]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C25H32ClN5O3
|
2
|
| 1 |
IC50 = 12.3 nM
|
|
|
| 2 |
IC50 = 179.52 nM
|
|
|
|
CP0573531
|
1-[4-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C26H33N7O3
|
2
|
| 1 |
IC50 = 12.32 nM
|
|
|
| 2 |
IC50 = 36.8 nM
|
|
|
|
CP0443939
|
3,4-dimethoxy-N-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]benzamide
Show/Hide
|
C28H33N7O5
|
2
|
| 1 |
IC50 = 12.57 nM
|
|
|
| 2 |
IC50 = 157.5 nM
|
|
|
|
CP0457419
|
N-[2-[[5-chloro-2-[4-(2-morpholin-4-ylethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C25H27ClN6O3
|
2
|
| 1 |
IC50 = 13.4 nM
|
|
|
| 2 |
IC50 = 491 nM
|
|
|
|
CP0576096
|
1-[4-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C25H30FN7O2
|
2
|
| 1 |
IC50 = 13.42 nM
|
|
|
| 2 |
IC50 = 119.04 nM
|
|
|
|
CP0565513
|
N-(3-bromophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H12BrN3O2
|
1
|
| 1 |
IC50 = 13.6 nM
|
|
|
|
CP0431411
|
(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-piperidin-1-ylbut-2-enamide
Show/Hide
|
C22H22ClFN6O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0572730
|
1-[4-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C26H32N6O3S
|
2
|
| 1 |
IC50 = 14.2 nM
|
|
|
| 2 |
IC50 = 246.9 nM
|
|
|
|
CP0374474
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[di(propan-2-yl)amino]but-2-enamide
Show/Hide
|
C34H39N7O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0483891
|
N-[2-[[5-chloro-2-[4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C24H25ClN6O2
|
2
|
| 1 |
IC50 = 15.3 nM
|
|
|
| 2 |
IC50 > 800 nM
|
|
|
|
CP0465700
|
N-(3-bromo-2,4-difluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H10BrF2N3O2
|
1
|
| 1 |
IC50 = 15.6 nM
|
|
|
|
CP0412869
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-phenylthiourea
Show/Hide
|
C21H16BrN5S
|
1
|
| 1 |
IC50 = 15.8 nM
|
|
|
|
CP0454551
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(2-chlorophenyl)thiourea
Show/Hide
|
C21H15BrClN5S
|
1
|
| 1 |
IC50 = 15.8 nM
|
|
|
|
CP0163871
|
4-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[(E)-morpholin-4-yliminomethyl]pyrimidine-4,6-diamine
Show/Hide
|
C23H23FN8O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0270656
|
4-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[(E)-(4-methylpiperazin-1-yl)iminomethyl]pyrimidine-4,6-diamine
Show/Hide
|
C24H26FN9
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0469119
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
|
C34H38N8O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0546823
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[[4-[(2R)-2-methylazetidin-1-yl]-1-propan-2-ylpyrido[3,4-d]pyridazin-7-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C24H31FN8O
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 8171 nM
|
|
|
|
CP0574136
|
N-(3-bromo-4-chloro-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H10BrClFN3O2
|
1
|
| 1 |
IC50 = 16.2 nM
|
|
|
|
CP0432974
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[(3S,5R)-3,5-dimethylpiperazin-1-yl]but-2-enamide
Show/Hide
|
C34H38N8O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0520421
|
N-[4-[(1-benzylindazol-5-yl)amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C26H24N6O2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0457418
|
N-[3-[[5-chloro-2-[2-methoxy-4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C25H27ClN6O3
|
2
|
| 1 |
IC50 = 17 nM
|
|
|
| 2 |
IC50 > 500 nM
|
|
|
|
CP0403368
|
1-benzyl-3-[4-(3-bromoanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C22H18BrN5S
|
1
|
| 1 |
IC50 = 17.2 nM
|
|
|
|
CP0444247
|
N-(2,3-difluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C16H11F2N3O2
|
1
|
| 1 |
IC50 = 18.9 nM
|
|
|
|
CP0453900
|
5-((4-aminopiperidin-1-yl)methyl)-N-(1-((5-methylpyridin-3-yl)methyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C26H29N9
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1
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| 1 |
IC50 = 19 nM
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CP0432357
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(4-amino-4-methylcyclohexyl) N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C30H34N8O2
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1
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| 1 |
IC50 = 19 nM
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CP0467076
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(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
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C22H23ClFN7O
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1
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| 1 |
IC50 = 19 nM
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CP0407952
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-chlorophenyl)urea
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C21H15BrClN5O
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1
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| 1 |
IC50 = 19.3 nM
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CP0407943
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-chlorophenyl)thiourea
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C21H15BrClN5S
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1
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| 1 |
IC50 = 19.5 nM
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CP0546495
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N-(3-ethynyl-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
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C18H12FN3O2
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1
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| 1 |
IC50 = 19.7 nM
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CP0485462
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4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylic acid
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C23H20N6O2
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1
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| 1 |
IC50 = 20 nM
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CP0442242
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N-[5-methyl-1-(1-prop-2-enoylpiperidin-3-yl)benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
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C24H23F3N4O2
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2
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 > 50000 nM
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CP0309077
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N-[(3E,5E)-1-methyl-3,5-bis[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-ylidene]hydroxylamine
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C22H28N6O
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1
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| 1 |
IC50 = 20 nM
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CP0566746
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(NZ)-N-[(3E,5E)-3-[(2-bromo-4,5-dimethoxyphenyl)methylidene]-1-methyl-5-[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-ylidene]hydroxylamine
Show/Hide
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C23H27BrN4O3
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1
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| 1 |
IC50 = 20 nM
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CP0477279
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4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-acetyloxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
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C36H57NO7
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3
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 100 nM
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| 3 |
IC50 > 20000 nM
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CP0568427
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1-[4-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
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C23H29ClN6O2
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2
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| 1 |
IC50 = 20.1 nM
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| 2 |
IC50 = 30.26 nM
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CP0495184
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1-[4-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
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C27H32N6O4S
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2
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| 1 |
IC50 = 20.23 nM
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| 2 |
IC50 = 60.74 nM
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CP0407880
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(3-chlorophenyl)thiourea
Show/Hide
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C21H15BrClN5S
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1
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| 1 |
IC50 = 20.6 nM
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CP0496951
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2-piperazin-1-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C29H33N9O2
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1
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| 1 |
IC50 = 21 nM
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CP0374478
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N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-2-methylprop-2-enamide
Show/Hide
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C25H27ClFN5O3
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1
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| 1 |
IC50 = 21 nM
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CP0379992
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(E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
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C30H32N6O4S
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1
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| 1 |
IC50 = 21 nM
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CP0432953
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N-[4-[(1-benzylindol-5-yl)amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
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C27H25N5O2
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1
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| 1 |
IC50 = 21 nM
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CP0444244
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N-(3,4-dibromo-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
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C16H10Br2FN3O2
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1
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| 1 |
IC50 = 21 nM
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CP0072495
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3-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]propan-1-ol
Show/Hide
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C25H21FN4O
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1
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| 1 |
IC50 = 21.1 nM
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CP0514142
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6-(4-aminophenyl)-N-[3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl]thieno[2,3-d]pyrimidin-4-amine
Show/Hide
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C25H16ClF3N4OS
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1
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| 1 |
IC50 = 21.4 nM
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CP0513310
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N-[2-[[5-chloro-2-[4-(3-morpholin-4-ylpropoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C26H29ClN6O3
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2
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| 1 |
IC50 = 21.5 nM
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| 2 |
IC50 = 766.6 nM
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CP0434909
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N-[2-[[5-chloro-2-[4-[(2-morpholin-4-ylacetyl)amino]anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C25H26ClN7O3
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2
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| 1 |
IC50 = 21.7 nM
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| 2 |
IC50 = 592.1 nM
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CP0406337
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(E)-N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]but-2-enamide
Show/Hide
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C25H27ClFN5O3
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1
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| 1 |
IC50 = 22 nM
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CP0407873
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]thiourea
Show/Hide
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C24H18BrN7O2S3
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1
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| 1 |
IC50 = 22 nM
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CP0538112
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3-(7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-ylamino)-2-fluorobenzonitrile
Show/Hide
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C17H11FN4O2
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1
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| 1 |
IC50 = 22 nM
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CP0475571
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(4-fluorophenyl)-4-oxobut-2-enoate
Show/Hide
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C26H21FO7
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1
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| 1 |
IC50 = 22.7 nM
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CP0418745
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[(3S)-morpholin-3-yl]methyl N-[5-ethyl-4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C28H29FN8O3
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1
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| 1 |
IC50 = 23 nM
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CP0496952
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(4-aminocyclohexyl) N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C29H32N8O2
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1
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| 1 |
IC50 = 23 nM
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CP0379993
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(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
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C33H36N8O2
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1
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| 1 |
IC50 = 23 nM
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CP0442803
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(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxyquinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
|
C32H34ClFN6O3
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1
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| 1 |
IC50 = 23 nM
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CP0556608
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(5-fluoro-2-methylphenyl)-4-oxobut-2-enoate
Show/Hide
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C27H23FO7
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1
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| 1 |
IC50 = 23.4 nM
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CP0546497
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3-(7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-ylamino)benzonitrile
Show/Hide
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C17H12N4O2
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1
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| 1 |
IC50 = 24 nM
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CP0490703
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N-[2-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C25H25ClN6O4
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2
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| 1 |
IC50 = 24.8 nM
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| 2 |
IC50 = 142.9 nM
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CP0406352
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(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
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C26H24ClFN6O2
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1
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| 1 |
IC50 = 25 nM
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CP0444245
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N-(3,4-dichloro-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
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C16H10Cl2FN3O2
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1
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| 1 |
IC50 = 25 nM
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CP0454552
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(3-chloro-4-fluorophenyl)thiourea
Show/Hide
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C21H14BrClFN5S
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1
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| 1 |
IC50 = 25.3 nM
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CP0340608
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(S)-N4-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((2-(methoxymethyl)pyrrolidin-1-ylimino)methyl)pyrimidine-4,6-diamine
Show/Hide
|
C25H27FN8O
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1
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| 1 |
IC50 = 26 nM
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CP0374470
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(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C32H33N7O3
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1
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| 1 |
IC50 = 26 nM
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CP0412872
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N-[4-(3-bromoanilino)quinazolin-6-yl]morpholine-4-carbothioamide
Show/Hide
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C19H18BrN5OS
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1
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| 1 |
IC50 = 26.9 nM
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CP0554108
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N-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C27H28F3N7O3
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2
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| 1 |
IC50 = 27.92 nM
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| 2 |
IC50 = 152.2 nM
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CP0558603
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-[(4-chlorophenyl)methyl]thiourea
Show/Hide
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C22H17BrClN5S
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1
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| 1 |
IC50 = 28.3 nM
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CP0427115
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4-(dimethylamino)-N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]butanamide
Show/Hide
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C32H33N5O3
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1
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| 1 |
IC50 = 29 nM
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CP0499123
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piperidin-4-ylmethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C29H32N8O2
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1
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| 1 |
IC50 = 30 nM
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CP0039472
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4-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[(E)-piperidin-1-yliminomethyl]pyrimidine-4,6-diamine
Show/Hide
|
C24H25FN8
|
1
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| 1 |
IC50 = 30 nM
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CP0146514
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N-[3-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
|
C22H26N8O2
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5
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| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 500 nM
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| 3 |
IC50 > 10000 nM
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| 4 |
Ki = 0.64 nM
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| 5 |
Ki = 70.2 nM
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CP0426072
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2-nitrooxyethyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C32H51NO6
|
3
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| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 110 nM
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| 3 |
IC50 > 20000 nM
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CP0163870
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(R,E)-N4-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((2-(methoxymethyl)pyrrolidin-1-ylimino)methyl)pyrimidine-4,6-diamine
Show/Hide
|
C25H27FN8O
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1
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| 1 |
IC50 = 31 nM
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CP0488435
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1-[4-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C27H33N7O4
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2
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| 1 |
IC50 = 31.35 nM
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| 2 |
IC50 = 132.65 nM
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CP0409402
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5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyrazin-2-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C23H25ClN8O
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1
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| 1 |
IC50 = 32 nM
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CP0227701
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[(3S)-morpholin-3-yl]methyl N-[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate
Show/Hide
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C27H27FN8O3
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1
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| 1 |
IC50 = 32 nM
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CP0475570
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(4-chlorophenyl)-4-oxobut-2-enoate
Show/Hide
|
C26H21ClO7
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1
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| 1 |
IC50 = 32.5 nM
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CP0531018
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1-[5-methoxy-4-[[4-[(3-methoxybenzoyl)amino]pyrimidin-2-yl]amino]-2-(prop-2-enoylamino)phenyl]piperidine-4-carboxamide
Show/Hide
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C28H31N7O5
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2
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| 1 |
IC50 = 32.61 nM
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| 2 |
IC50 = 50.5 nM
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CP0209615
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5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C26H27FN8
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1
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| 1 |
IC50 = 33 nM
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CP0510451
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[(3S)-morpholin-3-yl]methyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C28H30N8O3
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1
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| 1 |
IC50 = 33 nM
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CP0554109
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N-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]naphthalene-1-carboxamide
Show/Hide
|
C30H31N7O3
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2
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| 1 |
IC50 = 33.31 nM
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| 2 |
IC50 = 133.9 nM
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CP0483898
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5-(dimethylamino)-N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]pentanamide
Show/Hide
|
C33H35N5O3
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1
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| 1 |
IC50 = 34 nM
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CP0038066
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5-[(4-aminopiperidin-1-yl)methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H27FN8
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1
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| 1 |
IC50 = 35 nM
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CP0467823
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5-[[4-(aminomethyl)piperidin-1-yl]methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8
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1
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| 1 |
IC50 = 35 nM
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CP0489555
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N-hexadecyl-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
Show/Hide
|
C33H45NO5
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1
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| 1 |
IC50 = 35 nM
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CP0447298
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-bromophenyl)thiourea
Show/Hide
|
C21H15Br2N5S
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1
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| 1 |
IC50 = 35.4 nM
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CP0452779
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5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C24H26ClN7O
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1
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| 1 |
IC50 = 36 nM
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CP0379989
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N-[7-methoxy-4-(4-phenylmethoxyanilino)quinazolin-6-yl]propanamide
Show/Hide
|
C25H24N4O3
|
1
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| 1 |
IC50 = 36 nM
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CP0406339
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(E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C32H32N6O4S
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1
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| 1 |
IC50 = 36 nM
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CP0507077
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1-benzyl-3-[4-(3-methylanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C23H21N5S
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1
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| 1 |
IC50 = 36.8 nM
|
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CP0530498
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-pyridin-4-ylprop-2-enamide
Show/Hide
|
C31H29ClN8O3
|
3
|
| 1 |
IC50 = 37 nM
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|
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| 2 |
IC50 = 150 nM
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| 3 |
IC50 = 8700 nM
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CP0374477
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(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C28H26ClFN6O2
|
1
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| 1 |
IC50 = 37 nM
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CP0452780
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5-[(4-aminopiperidin-1-yl)methyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
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C25H26ClFN6O
|
1
|
| 1 |
IC50 = 38 nM
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CP0501034
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piperidin-3-ylmethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C29H32N8O2
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1
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| 1 |
IC50 = 38 nM
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CP0510452
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2-piperidin-1-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C30H34N8O2
|
1
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| 1 |
IC50 = 38 nM
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CP0458760
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(E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
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C30H30N6O4S
|
1
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| 1 |
IC50 = 38 nM
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CP0082996
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4-hydroxy-3-[4-(pyrazin-2-ylmethylamino)quinazolin-2-yl]benzonitrile
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C20H14N6O
|
2
|
| 1 |
IC50 = 38.7 nM
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| 2 |
IC50 > 50000 nM
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CP0254994
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2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}carbamate
Show/Hide
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C28H27N9O2
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1
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| 1 |
IC50 = 40 nM
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CP0483697
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4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(1H-imidazol-1-yl)propyl]pyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
Show/Hide
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C29H29N9O
|
1
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| 1 |
IC50 = 40 nM
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CP0459842
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5-[(4-aminopiperidin-1-yl)methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-6-methoxypyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
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C27H29FN8O
|
1
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| 1 |
IC50 = 40 nM
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CP0494681
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2-imidazol-1-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C28H27N9O2
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1
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| 1 |
IC50 = 40 nM
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CP0138773
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4-Anilinoquinazoline deriv. 45
Show/Hide
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C14H11BrN4
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1
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| 1 |
IC50 = 40 nM
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CP0310958
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6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1S)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Show/Hide
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C27H32N6
|
1
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| 1 |
IC50 = 40 nM
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CP0573650
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(3E,5E)-1-methyl-3,5-bis[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-one
Show/Hide
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C22H27N5O
|
1
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| 1 |
IC50 = 40 nM
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CP0402980
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4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
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C34H55NO7
|
3
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| 1 |
IC50 = 40 nM
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| 2 |
IC50 = 190 nM
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| 3 |
IC50 > 20000 nM
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CP0473347
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N-[2-[4-(dimethylamino)-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]-3,4-dimethoxybenzamide
Show/Hide
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C25H28N6O5
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2
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| 1 |
IC50 = 40.19 nM
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| 2 |
IC50 = 148.8 nM
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CP0364926
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N-[3-[[2-[4-(3-imidazol-1-ylpropoxy)anilino]-5-nitropyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C25H24N8O4
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2
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| 1 |
IC50 = 40.6 nM
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| 2 |
IC50 > 1000 nM
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CP0374476
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(E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
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C27H26N8O
|
1
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| 1 |
IC50 = 41 nM
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CP0540560
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N-[2-fluoro-3-(trifluoromethyl)phenyl]-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
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C17H11F4N3O2
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1
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| 1 |
IC50 = 41.4 nM
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CP0544268
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1-[4-[5-chloro-2-[4-[4-(2-hydroxyethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
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C24H31ClN6O3
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2
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| 1 |
IC50 = 42.06 nM
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| 2 |
IC50 = 123.7 nM
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CP0432356
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2-piperidin-4-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C30H34N8O2
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1
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| 1 |
IC50 = 44 nM
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CP0499124
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piperidin-2-ylmethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
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C29H32N8O2
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1
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| 1 |
IC50 = 45 nM
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CP0536379
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(4-methylphenyl)-4-oxobut-2-enoate
Show/Hide
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C27H24O7
|
1
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| 1 |
IC50 = 45.2 nM
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CP0567515
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N-[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C27H30F3N7O3
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2
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| 1 |
IC50 = 46.52 nM
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| 2 |
IC50 = 108.7 nM
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CP0511622
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5-((4-aminopiperidin-1-yl)methyl)-N-(1-(pyridin-2-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H27N9
|
1
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| 1 |
IC50 = 47 nM
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CP0434965
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N-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]methanesulfonamide
Show/Hide
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C26H18ClF3N4O3S2
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1
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| 1 |
IC50 = 47.1 nM
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CP0478911
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N-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]acetamide
Show/Hide
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C27H18ClF3N4O2S
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1
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| 1 |
IC50 = 47.7 nM
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CP0467822
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2-(1-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methyl)piperidin-4-ylamino)ethanol
Show/Hide
|
C28H31FN8O
|
1
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| 1 |
IC50 = 48 nM
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CP0484069
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5-((1,4-diazepan-1-yl)methyl)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H26ClFN6O
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1
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| 1 |
IC50 = 48 nM
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CP0430799
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hexadecyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
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C33H44O6
|
1
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| 1 |
IC50 = 48 nM
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CP0462401
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2-(dimethylamino)-N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]acetamide
Show/Hide
|
C30H29N5O3
|
1
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| 1 |
IC50 = 48 nM
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CP0444248
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N-(3-ethynylphenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
|
C18H13N3O2
|
1
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| 1 |
IC50 = 48.7 nM
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CP0561533
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(2,4-dichlorophenyl)thiourea
Show/Hide
|
C21H14BrCl2N5S
|
1
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| 1 |
IC50 = 48.9 nM
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CP0163869
|
4-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[(4-methoxyphenyl)iminomethyl]pyrimidine-4,6-diamine
Show/Hide
|
C26H22FN7O
|
1
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| 1 |
IC50 = 49 nM
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CP0483692
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ethyl 5-ethyl-4-(1H-indazol-5-ylamino)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
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C18H18N6O2
|
1
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| 1 |
IC50 = 50 nM
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CP0409406
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(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-aminopyrrolidin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H25FN8
|
1
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| 1 |
IC50 = 50 nM
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CP0464652
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5-[(4-amino-4-methylpiperidin-1-yl)methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8
|
1
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| 1 |
IC50 = 50 nM
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CP0428083
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N-[5-methyl-1-[3-(prop-2-enoylamino)propyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H21F3N4O2
|
2
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| 1 |
IC50 = 50 nM
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| 2 |
IC50 > 50000 nM
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CP0546834
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(3S,4R)-3-fluoro-1-[4-[[8-(methylamino)-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C21H26FN7O
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2
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| 1 |
IC50 = 50 nM
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| 2 |
IC50 > 10000 nM
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CP0443804
|
[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(4-ethylphenyl)-4-oxobut-2-enoate
Show/Hide
|
C28H26O7
|
1
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| 1 |
IC50 = 50.8 nM
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CP0814233
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N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-[(2,2,2-trifluoro-ethyl)-hydrazonomethyl]-pyrimidine-4,6-diamine
Show/Hide
|
C21H18F4N8
|
1
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| 1 |
IC50 = 52 nM
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CP0554107
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1-[4-[[4-[(3,4-dimethoxybenzoyl)amino]pyrimidin-2-yl]amino]-5-methoxy-2-(prop-2-enoylamino)phenyl]piperidine-4-carboxamide
Show/Hide
|
C29H33N7O6
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2
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| 1 |
IC50 = 54.69 nM
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| 2 |
IC50 = 128 nM
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CP0416866
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3-methoxy-N-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]benzamide
Show/Hide
|
C27H31N7O4
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2
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| 1 |
IC50 = 54.99 nM
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| 2 |
IC50 = 147.4 nM
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CP0458414
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1-[4-(3-chloroanilino)quinazolin-6-yl]-3-(5-chloropyridin-3-yl)thiourea
Show/Hide
|
C20H14Cl2N6S
|
1
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| 1 |
IC50 = 55.5 nM
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CP0431412
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(E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C29H28N8O
|
1
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| 1 |
IC50 = 57 nM
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CP0018477
|
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H16ClF3N4O3
|
1
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| 1 |
IC50 = 57 nM
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CP0562554
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N-[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]-3-methoxybenzamide
Show/Hide
|
C27H33N7O4
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2
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| 1 |
IC50 = 59 nM
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| 2 |
IC50 = 153.5 nM
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CP0399771
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ethyl 4-(3-bromoanilino)-5-ethylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C17H17BrN4O2
|
1
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| 1 |
IC50 = 60 nM
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CP0399584
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(R)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-aminopyrrolidin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H25FN8
|
1
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| 1 |
IC50 = 60 nM
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CP0467074
|
(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C31H31ClFN5O3
|
1
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| 1 |
IC50 = 60 nM
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CP0419522
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N-[5-methyl-1-[(1R,3R)-3-(prop-2-enoylamino)cyclohexyl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
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2
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| 1 |
IC50 = 60 nM
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| 2 |
IC50 > 50000 nM
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CP0407300
|
(3E,5E)-3-[(2-bromo-4,5-dimethoxyphenyl)methylidene]-1-methyl-5-[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-one
Show/Hide
|
C23H26BrN3O3
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1
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| 1 |
IC50 = 60 nM
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CP0474309
|
1-[4-(3-chloroanilino)quinazolin-6-yl]-3-(3,5-difluorophenyl)thiourea
Show/Hide
|
C21H14ClF2N5S
|
1
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| 1 |
IC50 = 60.1 nM
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CP0474307
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-[3-(trifluoromethyl)phenyl]thiourea
Show/Hide
|
C22H15BrF3N5S
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1
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| 1 |
IC50 = 60.7 nM
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CP0038067
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(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H26FN7O2
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1
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| 1 |
IC50 = 61 nM
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CP0432692
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N-[7-methoxy-4-[[1-(pyridin-2-ylmethyl)indol-5-yl]amino]quinazolin-6-yl]propanamide
Show/Hide
|
C26H24N6O2
|
1
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| 1 |
IC50 = 61 nM
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CP0453899
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N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[[4-(methylamino)piperidin-1-yl]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8
|
1
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| 1 |
IC50 = 63 nM
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CP0474303
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1-benzyl-3-[4-(3-hydroxyanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C22H19N5OS
|
1
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| 1 |
IC50 = 63.6 nM
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CP0431424
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N-[4-[4-(benzenesulfonamido)anilino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C24H23N5O4S
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1
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| 1 |
IC50 = 65 nM
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CP0476116
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N-[7-methoxy-4-(4-phenoxyanilino)quinazolin-6-yl]propanamide
Show/Hide
|
C24H22N4O3
|
1
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| 1 |
IC50 = 65 nM
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CP0559320
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1-[5-methoxy-2-(prop-2-enoylamino)-4-[[4-[[4-(trifluoromethyl)benzoyl]amino]pyrimidin-2-yl]amino]phenyl]piperidine-4-carboxamide
Show/Hide
|
C28H28F3N7O4
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2
|
| 1 |
IC50 = 65.34 nM
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| 2 |
IC50 = 127.2 nM
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CP0465177
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N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C25H22ClFN4O3
|
1
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| 1 |
IC50 = 67 nM
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CP0406340
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(E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxyquinazolin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C30H32N6O5S
|
1
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| 1 |
IC50 = 69 nM
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CP0456529
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4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-methylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
Show/Hide
|
C24H23N7O
|
1
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| 1 |
IC50 = 70 nM
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CP0511625
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5-[(4-aminopiperidin-1-yl)methyl]-N-[3-chloro-4-[(1-oxidopyridin-1-ium-2-yl)methoxy]phenyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C24H26ClN7O2
|
1
|
| 1 |
IC50 = 70 nM
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CP0285560
|
3-(3,4-Dimethylphenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C19H21N3OS
|
1
|
| 1 |
IC50 = 70 nM
|
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CP0356802
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N-[3-[4-(1H-indazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
|
C25H26N8O2
|
5
|
| 1 |
IC50 = 70 nM
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|
|
| 2 |
IC50 = 500 nM
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|
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| 3 |
IC50 = 1700 nM
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| 4 |
Ki = 0.32 nM
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| 5 |
Ki = 833 nM
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CP0801534
|
ERLOTINIB HYDROCHLORIDE
Show/Hide
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C22H24ClN3O4
|
1
|
| 1 |
IC50 = 70 nM
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CP0236216
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[3-oxo-3-[3-(pyridine-2-carbonylamino)anilino]propyl] 4-phenylpiperazine-1-carbodithioate
Show/Hide
|
C26H27N5O2S2
|
1
|
| 1 |
IC50 = 70 nM
|
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CP0467073
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[(2S,6R)-2,6-dimethylpiperazin-1-yl]but-2-enamide
Show/Hide
|
C34H38N8O2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
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CP0113747
|
2-methyl-N-[2-[3-(prop-2-enoylamino)anilino]pyrimidin-5-yl]-5-[[3-(trifluoromethyl)benzoyl]amino]benzamide
Show/Hide
|
C29H23F3N6O3
|
1
|
| 1 |
IC50 = 72 nM
|
|
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CP0076102
|
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
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C19H14FN3O3S
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1
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| 1 |
IC50 = 73.1 nM
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CP0534253
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2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide
Show/Hide
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C29H26FN5O3S
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1
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| 1 |
IC50 = 73.1 nM
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CP0431408
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(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[(2R,6S)-2,6-dimethylpiperidin-1-yl]but-2-enamide
Show/Hide
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C35H39N7O2
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1
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| 1 |
IC50 = 79 nM
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CP0489284
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N-[4-(1H-indazol-5-ylamino)-7-methoxyquinazolin-6-yl]propanamide
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C19H18N6O2
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1
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| 1 |
IC50 = 79 nM
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CP0489638
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1-(5-Chloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
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C21H19ClN2O2S
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1
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| 1 |
IC50 = 80 nM
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CP0427003
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4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)benzamide
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C18H20Cl2N2O2
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1
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| 1 |
IC50 = 80 nM
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CP0415555
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N-[3-[[5-fluoro-2-[4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C24H25FN6O2
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2
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| 1 |
IC50 = 80.8 nM
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| 2 |
IC50 = 500 nM
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CP0414600
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(1H-imidazol-5-yl)prop-2-enamide
Show/Hide
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C29H28ClN9O3
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3
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| 1 |
IC50 = 81 nM
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| 2 |
IC50 = 350 nM
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| 3 |
IC50 > 10000 nM
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CP0432690
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(E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxyquinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
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C31H35N7O4S
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1
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| 1 |
IC50 = 82 nM
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CP0115156
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopropylprop-2-enamide
Show/Hide
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C29H30ClN7O3
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3
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| 1 |
IC50 = 83 nM
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| 2 |
IC50 = 350 nM
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| 3 |
IC50 = 7200 nM
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CP0343779
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[2-oxo-2-[3-(pyridine-2-carbonylamino)anilino]ethyl] piperidine-1-carbodithioate
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C20H22N4O2S2
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1
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| 1 |
IC50 = 84 nM
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CP0452778
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5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-((5-methylpyridin-3-yl)methoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C25H28ClN7O
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1
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| 1 |
IC50 = 85 nM
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CP0379986
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N-[7-methoxy-4-[[(1R)-1-phenylethyl]amino]quinazolin-6-yl]propanamide
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C20H22N4O2
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1
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| 1 |
IC50 = 86 nM
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CP0380019
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N-[4-[[1-(furan-2-ylmethyl)indol-5-yl]amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
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C25H23N5O3
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1
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| 1 |
IC50 = 86 nM
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CP0483691
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ethyl 4-(3-chloro-4-fluoroanilino)-5-ethylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
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C17H16ClFN4O2
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1
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| 1 |
IC50 = 90 nM
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CP0859705
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2-(2-(5-Bromo-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
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C10H8BrN3O2S
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1
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| 1 |
IC50 = 90 nM
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CP0427002
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4-(Bis(2-chloroethyl)amino)-N-(1-naphthyl)benzamide
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C21H20Cl2N2O
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1
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| 1 |
IC50 = 90 nM
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CP0508917
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5-bromo-N-(4-chlorophenyl)sulfonylpyridine-3-carboxamide
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C12H8BrClN2O3S
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1
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| 1 |
IC50 = 90 nM
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CP0509089
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ethyl 2-amino-5-oxo-1-pyridin-3-yl-4-(tetrazolo[1,5-a]quinolin-4-yl)-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
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C26H23N7O3
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1
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| 1 |
IC50 = 90 nM
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CP0445872
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N-[1-(4-hydroxycyclohexyl)-7-methylbenzimidazol-2-yl]-3-(trifluoromethyl)benzamide
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C22H22F3N3O2
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3
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| 1 |
IC50 = 90 nM
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| 2 |
IC50 = 680 nM
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| 3 |
IC50 = 5270 nM
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CP0444135
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1-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]-3-(2-morpholin-4-ylethyl)urea
Show/Hide
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C32H28ClF3N6O3S
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1
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| 1 |
IC50 = 91.7 nM
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CP0380015
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N-[7-methoxy-4-[[1-(pyridin-2-ylmethyl)indazol-5-yl]amino]quinazolin-6-yl]propanamide
Show/Hide
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C25H23N7O2
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1
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| 1 |
IC50 = 94 nM
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CP0422009
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N-[3-[[5-chloro-2-[4-(2-morpholin-4-ylethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C25H27ClN6O3
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2
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| 1 |
IC50 = 94.7 nM
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| 2 |
IC50 = 961.3 nM
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CP0393198
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N-[3-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethyl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C25H25ClN6O3
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2
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| 1 |
IC50 = 96.6 nM
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| 2 |
IC50 < 500 nM
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CP0374472
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(E)-N-[7-ethoxy-4-[4-(pyridin-2-ylmethoxy)anilino]quinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
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C30H32N6O3
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1
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| 1 |
IC50 = 98 nM
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CP0514476
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N-[3-[[2-(4-imidazol-1-ylanilino)-5-nitropyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C22H18N8O3
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2
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| 1 |
IC50 = 98.2 nM
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| 2 |
IC50 > 1000 nM
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CP0568870
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6-[[2-[(3S,4R)-3-fluoro-4-hydroxypiperidin-1-yl]pyrimidin-4-yl]amino]-N-methyl-4-(propan-2-ylamino)pyridine-3-carboxamide
Show/Hide
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C19H26FN7O2
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2
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| 1 |
IC50 = 99 nM
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| 2 |
IC50 > 10000 nM
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CP0452781
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5-[[4-(dimethylamino)piperidin-1-yl]methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
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C28H31FN8
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1
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| 1 |
IC50 = 100 nM
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CP0469857
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N-[3-[4-(1H-pyrazol-5-ylamino)quinazolin-2-yl]phenyl]prop-2-enamide
Show/Hide
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C20H16N6O
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3
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| 1 |
IC50 = 100 nM
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| 2 |
IC50 = 500 nM
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| 3 |
IC50 = 1100 nM
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CP0514509
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N-[3-[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Show/Hide
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C25H24ClN5O4
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2
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| 1 |
IC50 = 100.5 nM
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| 2 |
IC50 = 996 nM
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CP0444052
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N-[3-[[5-nitro-2-[4-[3-(tetrazol-1-yl)propoxy]anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C23H22N10O4
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2
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| 1 |
IC50 = 100.6 nM
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| 2 |
IC50 > 1000 nM
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CP0396178
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N-[3-[[5-chloro-2-[4-[2-(1,2,4-triazol-1-yl)ethoxy]anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C23H21ClN8O2
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2
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| 1 |
IC50 = 103.4 nM
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| 2 |
IC50 > 1000 nM
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CP0437968
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(2-chloro-4-methylphenyl)-4-oxobut-2-enoate
Show/Hide
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C27H23ClO7
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1
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| 1 |
IC50 = 105.3 nM
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CP0180443
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N-[3-[[5-chloro-2-[4-(2-imidazol-1-ylethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C24H22ClN7O2
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2
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| 1 |
IC50 = 106 nM
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| 2 |
IC50 > 1000 nM
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CP0545096
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(3S,4R)-3-fluoro-3-methyl-1-[4-[[8-[(2S)-2-methylazetidin-1-yl]-5-propan-2-yl-2,7-naphthyridin-3-yl]amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
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C25H32FN7O
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2
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| 1 |
IC50 = 106 nM
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| 2 |
IC50 = 10000 nM
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CP0542132
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(3-fluoro-4-methylphenyl)-4-oxobut-2-enoate
Show/Hide
|
C27H23FO7
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1
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| 1 |
IC50 = 107.2 nM
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CP0452714
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N-[3-[[5-chloro-2-[4-(imidazol-1-ylmethyl)-2-methoxyanilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
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C24H22ClN7O2
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2
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| 1 |
IC50 = 109 nM
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| 2 |
IC50 = 506 nM
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CP0467824
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N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[(piperidin-4-ylamino)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H27FN8
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1
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| 1 |
IC50 = 110 nM
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CP0511624
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N-[1-[[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-4-yl]-2-hydroxyacetamide
Show/Hide
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C28H29FN8O2
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1
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| 1 |
IC50 = 110 nM
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CP0472044
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2-morpholin-4-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C29H32N8O3
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1
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| 1 |
IC50 = 111 nM
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CP0481820
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1-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]-3-cyclopropylurea
Show/Hide
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C29H21ClF3N5O2S
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1
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| 1 |
IC50 = 112 nM
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CP0454553
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-[2-fluoro-3-(trifluoromethyl)phenyl]thiourea
Show/Hide
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C22H14BrF4N5S
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1
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| 1 |
IC50 = 112.4 nM
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CP0473244
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N-[7-methoxy-4-[4-(pyridin-2-ylmethoxy)anilino]quinazolin-6-yl]propanamide
Show/Hide
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C24H23N5O3
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1
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| 1 |
IC50 = 116 nM
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CP0412278
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(3,4-dimethylphenyl)-4-oxobut-2-enoate
Show/Hide
|
C28H26O7
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1
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| 1 |
IC50 = 118.6 nM
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CP0396179
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N-[3-[[2-[4-[(2-imidazol-1-ylacetyl)amino]anilino]-5-nitropyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C24H21N9O4
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2
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| 1 |
IC50 = 118.7 nM
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| 2 |
IC50 > 1000 nM
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CP0475567
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(4-bromophenyl)-4-oxobut-2-enoate
Show/Hide
|
C26H21BrO7
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1
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| 1 |
IC50 = 119.7 nM
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CP0456526
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ethyl 4-[(1-benzylindazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C23H20N6O2
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1
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| 1 |
IC50 = 120 nM
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CP0483696
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4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
Show/Hide
|
C23H21N7O
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1
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| 1 |
IC50 = 120 nM
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CP0485460
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ethyl 4-[(1-benzylindazol-5-yl)amino]-5-ethylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C25H24N6O2
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1
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| 1 |
IC50 = 120 nM
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CP0489639
|
1-(5-Bromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C21H19BrN2O2S
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1
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| 1 |
IC50 = 120 nM
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CP0534790
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(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(3-nitrophenyl)prop-2-enamide
Show/Hide
|
C23H16BrN5O3
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1
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| 1 |
IC50 = 120 nM
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CP0540326
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N-[(E)-[2-(4-methoxyphenoxy)-6-methylquinolin-3-yl]methylideneamino]-2-(2-methyl-5-nitroimidazol-1-yl)acetamide
Show/Hide
|
C24H22N6O5
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2
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| 1 |
IC50 = 120 nM
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| 2 |
IC50 = 2180 nM
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CP0518144
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2-[5-(3,4-dimethylphenyl)-3-naphthalen-2-yl-3,4-dihydropyrazol-2-yl]-1,3-thiazol-4-one
Show/Hide
|
C24H21N3OS
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1
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| 1 |
IC50 = 120 nM
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CP0445502
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-fluorophenyl)prop-2-enamide
Show/Hide
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C32H29ClFN7O3
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3
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| 1 |
IC50 = 120 nM
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| 2 |
IC50 = 540 nM
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| 3 |
IC50 = 7000 nM
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CP0407946
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1-[4-(3-chloroanilino)quinazolin-6-yl]-3-(5-chloro-1,3-thiazol-2-yl)thiourea
Show/Hide
|
C18H12Cl2N6S2
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1
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| 1 |
IC50 = 120 nM
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CP0458415
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1-[4-(3-chloroanilino)quinazolin-6-yl]-3-(5-methyl-1,3,4-thiadiazol-2-yl)thiourea
Show/Hide
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C18H14ClN7S2
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1
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| 1 |
IC50 = 120 nM
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CP0550961
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(2-fluoro-4-methylphenyl)-4-oxobut-2-enoate
Show/Hide
|
C27H23FO7
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1
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| 1 |
IC50 = 120.2 nM
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CP0390838
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N-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]benzamide
Show/Hide
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C26H29N7O3
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2
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| 1 |
IC50 = 120.7 nM
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| 2 |
IC50 = 156.5 nM
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CP0380017
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(E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxyquinazolin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C32H32N6O5S
|
1
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| 1 |
IC50 = 122 nM
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CP0007430
|
IBRUTINIB
Show/Hide
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C25H24N6O2
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1
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| 1 |
IC50 = 123 nM
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CP0564561
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N-[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]-3,4-dimethoxybenzamide
Show/Hide
|
C28H35N7O5
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2
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| 1 |
IC50 = 123.2 nM
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| 2 |
IC50 = 187.2 nM
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CP0578163
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1-[4-[2-[(1-methylpyrazol-3-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C18H20N6O2S
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2
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| 1 |
IC50 = 126 nM
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| 2 |
IC50 = 224 nM
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CP0471252
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N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C26H23N5O4S
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1
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| 1 |
IC50 = 127 nM
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CP0452148
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3-(3,4-Dimethylphenyl)-5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C18H19N3OS
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1
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| 1 |
IC50 = 130 nM
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CP0458416
|
1-[4-(3-chloroanilino)quinazolin-6-yl]-3-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]thiourea
Show/Hide
|
C18H11ClF3N7S2
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1
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| 1 |
IC50 = 130 nM
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CP0431410
|
(E)-N-[7-methoxy-4-(4-phenoxyanilino)quinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
Show/Hide
|
C30H31N5O3
|
1
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| 1 |
IC50 = 132 nM
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CP0407874
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(3,4-dichlorophenyl)thiourea
Show/Hide
|
C21H14BrCl2N5S
|
1
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| 1 |
IC50 = 133.1 nM
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CP0545479
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1-[4-[2-[(1-methylpyrazol-4-yl)amino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C18H20N6O2S
|
2
|
| 1 |
IC50 = 135 nM
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| 2 |
IC50 = 196.02 nM
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CP0484499
|
N-[4-(benzylamino)-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
IC50 = 136 nM
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CP0412870
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1-[4-(3-chloroanilino)quinazolin-6-yl]-3-[4-(trifluoromethyl)-1,3-thiazol-2-yl]thiourea
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C19H12ClF3N6S2
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1
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| 1 |
IC50 = 137 nM
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CP0704687
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shikonin
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C16H16O5
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1
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| 1 |
IC50 = 139.2 nM
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CP0485694
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N-[1-(4-hydroxycyclohexyl)-5-methylbenzimidazol-2-yl]-3-(trifluoromethyl)benzamide
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C22H22F3N3O2
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3
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| 1 |
IC50 = 140 nM
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| 2 |
IC50 > 11780 nM
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| 3 |
IC50 > 8480 nM
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CP0476595
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N-[2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]pyrimidin-4-yl]benzamide
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C26H31N7O3
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2
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| 1 |
IC50 = 142.7 nM
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| 2 |
IC50 = 317.6 nM
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CP0470485
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[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(5-chloro-2-methylphenyl)-4-oxobut-2-enoate
Show/Hide
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C27H23ClO7
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1
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| 1 |
IC50 = 146.2 nM
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CP0513580
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1-[4-(3-bromoanilino)quinazolin-6-yl]-3-(3,5-dichlorophenyl)thiourea
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C21H14BrCl2N5S
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1
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| 1 |
IC50 = 146.3 nM
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CP0348177
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N-[3-(cyclohexylcarbamoylamino)phenyl]pyridine-2-carboxamide
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C19H22N4O2
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1
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| 1 |
IC50 = 147 nM
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CP0431358
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(E)-N-[7-methoxy-4-[4-(pyridin-2-ylmethyl)anilino]quinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
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C29H30N6O2
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1
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| 1 |
IC50 = 148 nM
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CP0511627
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5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyridin-3-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C24H26ClN7O
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1
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| 1 |
IC50 = 150 nM
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CP0431360
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(E)-N-[7-ethoxy-4-[4-(pyridin-2-ylmethoxy)anilino]quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
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C31H35N7O3
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1
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| 1 |
IC50 = 164 nM
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CP0485715
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3-(1H-imidazol-1-yl)propyl 4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate
Show/Hide
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C29H28N8O2
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1
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| 1 |
IC50 = 170 nM
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CP0467071
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N-[4-[(1-benzyl-2,3-dihydroindol-5-yl)amino]-7-methoxyquinazolin-6-yl]propanamide
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C27H27N5O2
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1
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| 1 |
IC50 = 175 nM
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CP0455269
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N-[4-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]acetamide
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C28H24N4O3
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1
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| 1 |
IC50 = 179 nM
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CP0395481
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N-[(E)-[6-methyl-2-(4-methylphenoxy)quinolin-3-yl]methylideneamino]-2-(2-methyl-5-nitroimidazol-1-yl)acetamide
Show/Hide
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C24H22N6O4
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2
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| 1 |
IC50 = 180 nM
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| 2 |
IC50 = 17000 nM
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CP0408612
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N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]acetamide
Show/Hide
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C24H27ClN6O3
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3
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| 1 |
IC50 = 180 nM
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| 2 |
IC50 = 490 nM
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| 3 |
IC50 > 10000 nM
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CP0464953
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(E)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
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C27H26N6O2
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1
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| 1 |
IC50 = 180 nM
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CP0453901
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5-((4-aminopiperidin-1-yl)methyl)-N-(1-(pyridin-3-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C25H27N9
|
1
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| 1 |
IC50 = 190 nM
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CP0511623
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5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-6-methoxypyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
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C27H29FN8O
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1
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| 1 |
IC50 = 190 nM
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CP0490282
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(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-(3-nitrophenyl)prop-2-enamide
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C23H16ClN5O3
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1
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| 1 |
IC50 = 190 nM
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CP0399774
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ethyl 4-[(1-benzylindazol-5-yl)amino]-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
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C24H22N6O2
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1
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| 1 |
IC50 = 200 nM
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CP0436087
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4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N,N-dimethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
Show/Hide
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C25H25N7O
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1
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| 1 |
IC50 = 200 nM
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CP0456527
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ethyl 4-[(1-benzylindazol-5-yl)amino]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
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C26H26N6O2
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1
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| 1 |
IC50 = 200 nM
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CP0483693
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4-Benzylamino-5-ethyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester
Show/Hide
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C18H20N4O2
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1
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| 1 |
IC50 = 200 nM
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CP0409404
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N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[[4-(2-methylsulfonylethylamino)piperidin-1-yl]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
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C29H33FN8O2S
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1
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| 1 |
IC50 = 200 nM
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CP0190702
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Anilinoquinazoline, 4c
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C14H11ClN4
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1
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| 1 |
IC50 = 200 nM
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CP0379899
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ethyl 2-amino-4-(7-methoxytetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
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C27H25N7O4
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1
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| 1 |
IC50 = 200 nM
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CP0385946
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N-[3-[4-(4-acetylpiperazin-1-yl)-6-(1H-indazol-3-ylamino)pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
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C26H26N8O3
|
3
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| 1 |
IC50 = 200 nM
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| 2 |
IC50 = 600 nM
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| 3 |
IC50 = 3600 nM
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CP0484469
|
(E)-4-(dimethylamino)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Show/Hide
|
C25H24N6O2
|
1
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| 1 |
IC50 = 201 nM
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CP0422550
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(2S)-2-[[5-(3-aminophenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino]-2-phenylethanol
Show/Hide
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C26H22N4O2
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1
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| 1 |
IC50 = 203 nM
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CP0575071
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1-[4-[[2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidin-1-yl]prop-2-en-1-one
Show/Hide
|
C18H21N7O2
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2
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| 1 |
IC50 = 203.8 nM
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| 2 |
IC50 = 387.42 nM
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CP0379988
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N-[7-methoxy-4-[4-(pyridin-2-ylmethyl)anilino]quinazolin-6-yl]propanamide
Show/Hide
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C24H23N5O2
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1
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| 1 |
IC50 = 205 nM
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CP0399775
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benzyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate
Show/Hide
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C30H27N7O2
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1
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| 1 |
IC50 = 210 nM
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CP0918204
|
(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)-4-hydroxybenzohydrazide
Show/Hide
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C19H16BrN5O4
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1
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| 1 |
IC50 = 210 nM
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CP0565987
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N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]acetamide
Show/Hide
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C28H24N4O3
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1
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| 1 |
IC50 = 218 nM
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CP0878675
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2-(5-(4-Bromophenyl)-3-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C19H16BrN3OS
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1
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| 1 |
IC50 = 240 nM
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CP0554328
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(2S)-2-[[5-(1,3-benzodioxol-5-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino]-2-phenylethanol
Show/Hide
|
C27H21N3O4
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1
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| 1 |
IC50 = 258 nM
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CP0465103
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N-[1-(4-hydroxycyclohexyl)benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
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C21H20F3N3O2
|
3
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| 1 |
IC50 = 260 nM
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| 2 |
IC50 = 2000 nM
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| 3 |
IC50 > 50000 nM
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CP0575964
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1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]propan-1-one
Show/Hide
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C25H32N6O2S
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2
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| 1 |
IC50 = 267.54 nM
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| 2 |
IC50 = 356.26 nM
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CP0395491
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N-[(E)-[2-(4-methoxyphenoxy)quinolin-3-yl]methylideneamino]-2-(2-methyl-5-nitroimidazol-1-yl)acetamide
Show/Hide
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C23H20N6O5
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2
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| 1 |
IC50 = 270 nM
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| 2 |
IC50 = 12020 nM
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CP0465104
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N-[1-(4-hydroxycyclohexyl)-6-methylbenzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
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C22H22F3N3O2
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3
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| 1 |
IC50 = 280 nM
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| 2 |
IC50 > 16000 nM
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| 3 |
IC50 > 50000 nM
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CP0544963
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N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-6-fluoro-3-hydroxy-2-[(3-oxo-1H-isoindol-2-yl)methyl]benzamide
Show/Hide
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C33H27FN6O4S
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2
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| 1 |
IC50 = 280 nM
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| 2 |
IC50 > 1000 nM
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CP0545097
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6-[[2-(4-hydroxypiperidin-1-yl)pyrimidin-4-yl]amino]-N-methyl-4-(propan-2-ylamino)pyridine-3-carboxamide
Show/Hide
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C19H27N7O2
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2
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| 1 |
IC50 = 290 nM
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| 2 |
IC50 > 10000 nM
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CP0385949
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N-[2-phenyl-6-(1H-pyrazol-5-ylamino)pyrimidin-4-yl]prop-2-enamide
Show/Hide
|
C16H14N6O
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3
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| 1 |
IC50 = 300 nM
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| 2 |
IC50 = 800 nM
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| 3 |
IC50 = 900 nM
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CP0385953
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N-[3-[4-[(5-bromo-1H-indazol-3-yl)amino]-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
|
C25H25BrN8O2
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3
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| 1 |
IC50 = 300 nM
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| 2 |
IC50 = 400 nM
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| 3 |
IC50 = 2900 nM
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CP0431430
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(E)-4-(dimethylamino)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Show/Hide
|
C25H25N7O
|
1
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| 1 |
IC50 = 304 nM
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CP0502039
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2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-tetradecylacetamide
Show/Hide
|
C31H41NO5
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1
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| 1 |
IC50 = 316 nM
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CP0410836
|
(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(furan-2-yl)prop-2-enamide
Show/Hide
|
C30H28ClN7O4
|
3
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| 1 |
IC50 = 330 nM
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| 2 |
IC50 = 1300 nM
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| 3 |
IC50 > 10000 nM
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CP0540894
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[3-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]phenyl]methanamine
Show/Hide
|
C29H22FN5
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1
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| 1 |
IC50 = 336 nM
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CP0471052
|
3-(3,4-Dimethylphenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C19H21N3S
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1
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| 1 |
IC50 = 340 nM
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CP0432693
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N-[4-[4-[hydroxy(phenyl)methyl]anilino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C25H24N4O3
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1
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| 1 |
IC50 = 343 nM
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CP0935721
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(Z)-2-((E)-3-phenyl-1-p-tolylallylidene)hydrazinecarbothioamide
Show/Hide
|
C17H17N3S
|
1
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| 1 |
IC50 = 350 nM
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CP0526522
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(2S)-2-[[5-(furan-3-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino]-2-phenylethanol
Show/Hide
|
C24H19N3O3
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1
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| 1 |
IC50 = 352 nM
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CP0531586
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(E)-4-(dimethylamino)-N-[[3-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]phenyl]methyl]but-2-enamide
Show/Hide
|
C35H31FN6O
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1
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| 1 |
IC50 = 364 nM
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CP0381613
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N-[(E)-[2-(4-fluorophenoxy)quinolin-3-yl]methylideneamino]-2-(2-methyl-5-nitroimidazol-1-yl)acetamide
Show/Hide
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C22H17FN6O4
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2
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| 1 |
IC50 = 370 nM
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| 2 |
IC50 = 21020 nM
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CP0516402
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N-[1-[[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C28H29FN8O
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1
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| 1 |
IC50 = 380 nM
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CP0380020
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N-[4-[4-(benzylamino)anilino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C25H25N5O2
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1
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| 1 |
IC50 = 383 nM
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CP0442810
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N-[7-methoxy-4-[4-(pyridin-4-ylmethyl)anilino]quinazolin-6-yl]propanamide
Show/Hide
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C24H23N5O2
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1
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| 1 |
IC50 = 388 nM
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CP0117004
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(2S)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol
Show/Hide
|
C26H21N3O2
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1
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| 1 |
IC50 = 393 nM
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CP0250168
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(2E,6E)-2-[(3,4-dihydroxyphenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H22O5
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1
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| 1 |
IC50 = 400 nM
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CP0501242
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4,4-dimethylpent-2-enamide
Show/Hide
|
C30H34ClN7O3
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3
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| 1 |
IC50 = 400 nM
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| 2 |
IC50 = 1300 nM
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| 3 |
IC50 > 10000 nM
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CP0401564
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N-[3-[4-(1H-pyrazol-5-ylamino)quinazolin-2-yl]phenyl]propanamide
Show/Hide
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C20H18N6O
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3
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| 1 |
IC50 = 400 nM
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| 2 |
IC50 = 1900 nM
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| 3 |
IC50 = 3700 nM
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CP0432972
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(E)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C27H27N7O
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1
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| 1 |
IC50 = 405 nM
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CP0919217
|
(Z)-2-((E)-3-(naphthalen-1-yl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C20H17N3S
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1
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| 1 |
IC50 = 410 nM
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CP0411583
|
N-[(E)-[2-(4-fluorophenoxy)-6-methylquinolin-3-yl]methylideneamino]-2-(2-methyl-5-nitroimidazol-1-yl)acetamide
Show/Hide
|
C23H19FN6O4
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2
|
| 1 |
IC50 = 420 nM
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| 2 |
IC50 = 430 nM
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CP0484471
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N-[7-methoxy-4-[[1-(2-methylpropyl)indol-5-yl]amino]quinazolin-6-yl]propanamide
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
IC50 = 421 nM
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CP0364775
|
(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-6-methoxy-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H28FN7O3
|
1
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| 1 |
IC50 = 430 nM
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CP0956570
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(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)-4-amino-benzohydrazide
Show/Hide
|
C19H17BrN6O3
|
1
|
| 1 |
IC50 = 430 nM
|
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CP0565988
|
(2S)-2-[[5-(furan-2-yl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino]-2-phenylethanol
Show/Hide
|
C24H19N3O3
|
1
|
| 1 |
IC50 = 434 nM
|
|
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CP0689377
|
SPEBRUTINIB
Show/Hide
|
C22H22FN5O3
|
1
|
| 1 |
IC50 = 442 nM
|
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CP0554329
|
(2S)-2-[(5-bromo-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol
Show/Hide
|
C20H16BrN3O2
|
1
|
| 1 |
IC50 = 452 nM
|
|
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CP0453059
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2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-octadecylacetamide
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C35H49NO5
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1
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| 1 |
IC50 = 464 nM
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CP0395767
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N-[5-(ethoxymethyl)-1-(4-hydroxycyclohexyl)benzimidazol-2-yl]-3-(trifluoromethyl)benzamide
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C24H26F3N3O3
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3
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| 1 |
IC50 = 470 nM
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| 2 |
IC50 = 2080 nM
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| 3 |
IC50 > 42000 nM
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CP0432588
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[4-[(1-benzylindazol-5-yl)amino]-5-ethylpyrrolo[2,1-f][1,2,4]triazin-6-yl]methanol
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C23H22N6O
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1
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| 1 |
IC50 = 490 nM
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CP0189377
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5-chloro-N-(1-hydroxy-3-phenylpropan-2-yl)-3-methyl-1H-indole-2-carboxamide
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C19H19ClN2O2
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1
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| 1 |
IC50 = 500 nM
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CP0493872
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N-[4-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]phenyl]-6-methylthieno[2,3-b]quinoline-2-carboxamide
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C30H24N2O4S
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1
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| 1 |
IC50 = 500 nM
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CP0565822
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2-bromo-6-(7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-ylamino)phenol
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C16H12BrN3O3
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1
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| 1 |
IC50 = 505.1 nM
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CP0379987
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N-[4-[4-(1,3-benzodioxol-5-yloxy)anilino]-7-methoxyquinazolin-6-yl]propanamide
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C25H22N4O5
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1
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| 1 |
IC50 = 509 nM
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CP0382276
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ethyl 2-amino-4-[5-chloro-3-methyl-1-(4-methylphenyl)pyrazol-4-yl]-7,7-dimethyl-5-oxo-1-pyridin-3-yl-6,8-dihydro-4H-quinoline-3-carboxylate
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C30H32ClN5O3
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1
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| 1 |
IC50 = 510 nM
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CP0445503
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-methylsulfanylphenyl)prop-2-enamide
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C33H32ClN7O3S
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3
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| 1 |
IC50 = 510 nM
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| 2 |
IC50 = 830 nM
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| 3 |
IC50 = 4800 nM
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CP0432973
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N-[7-methoxy-4-[[1-(pyridin-2-ylmethyl)-2,3-dihydroindol-5-yl]amino]quinazolin-6-yl]propanamide
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C26H26N6O2
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1
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| 1 |
IC50 = 519 nM
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CP0458759
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N-[4-[[6-(benzenesulfonamido)pyridin-3-yl]amino]-7-methoxyquinazolin-6-yl]propanamide
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C23H22N6O4S
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1
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| 1 |
IC50 = 522 nM
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CP0511633
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5-((4-aminopiperidin-1-yl)methyl)-N-(1-(pyridin-4-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
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C25H27N9
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1
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| 1 |
IC50 = 530 nM
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CP0540311
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N-[7-methoxy-4-(4-pyridin-3-yloxyanilino)quinazolin-6-yl]propanamide
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C23H21N5O3
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1
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| 1 |
IC50 = 531 nM
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CP0364773
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(S)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
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C25H25ClFN5O3
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1
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| 1 |
IC50 = 560 nM
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CP0853154
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2-(2-(5-Chloro-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
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C10H8ClN3O2S
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1
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| 1 |
IC50 = 560 nM
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CP0430870
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1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
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C21H18Cl2N2O2S
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1
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| 1 |
IC50 = 560 nM
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CP0383875
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4-(Bis(2-chloroethyl)amino)-N-p-tolylbenzamide
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C18H20Cl2N2O
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1
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| 1 |
IC50 = 580 nM
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CP0499767
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(2S)-2-[(5-chloro-6-phenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol
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C20H16ClN3O2
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1
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| 1 |
IC50 = 589 nM
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CP0939807
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(Z)-2-((E)-1-(4-chlorophenyl)-3-phenylallylidene)hydrazinecarbothioamide
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C16H14ClN3S
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1
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| 1 |
IC50 = 590 nM
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CP0431425
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N-[4-[4-(benzenesulfonamido)-3-fluoroanilino]-7-methoxyquinazolin-6-yl]propanamide
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C24H22FN5O4S
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1
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| 1 |
IC50 = 593 nM
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CP0410808
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N-[2-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
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C22H26N8O2
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3
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| 1 |
IC50 = 600 nM
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| 2 |
IC50 = 900 nM
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| 3 |
IC50 = 2100 nM
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CP0567338
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N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-(3-nitrophenoxy)pyrimidin-4-amine (14)
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C19H22N8O3
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3
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| 1 |
IC50 = 600 nM
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| 2 |
IC50 = 2300 nM
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| 3 |
IC50 = 3900 nM
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CP0483694
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ethyl 5-ethyl-4-(4-phenoxyanilino)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
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C23H22N4O3
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1
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| 1 |
IC50 = 610 nM
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CP0198957
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-phenyl)acrylate
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C21H19N3O4
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1
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| 1 |
IC50 = 620 nM
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CP0518143
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2-[5-(3,4-dimethylphenyl)-3-naphthalen-2-yl-3,4-dihydropyrazol-2-yl]-4-phenyl-4,5-dihydro-1,3-thiazole
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C30H27N3S
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1
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| 1 |
IC50 = 650 nM
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CP0489636
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1-(5-Chloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
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C21H18ClFN2OS
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1
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| 1 |
IC50 = 670 nM
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CP0006184
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6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione
Show/Hide
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C14H6O8
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1
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| 1 |
IC50 = 690 nM
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CP0517555
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octadecyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
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C35H48O6
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1
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| 1 |
IC50 = 692 nM
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CP0941578
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(Z)-2-((E)-3-(4-(benzyloxy)phenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
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C23H21N3OS
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1
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| 1 |
IC50 = 700 nM
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CP0380593
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N-(4-((4-((5-Methyl-1H-pyrazol-3-yl)amino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl)oxy)phenyl)propionamide (24)
Show/Hide
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C22H28N8O2
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3
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| 1 |
IC50 = 700 nM
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| 2 |
IC50 = 1900 nM
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| 3 |
IC50 > 10000 nM
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CP0488090
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(E)-4-(dimethylamino)-N-[3-[4-(1H-indazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]oxyphenyl]but-2-enamide
Show/Hide
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C28H33N9O2
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3
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| 1 |
IC50 = 700 nM
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| 2 |
IC50 = 3600 nM
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| 3 |
IC50 = 6700 nM
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CP0571430
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N-[4-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]phenyl]-6-methoxythieno[2,3-b]quinoline-2-carboxamide
Show/Hide
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C30H24N2O5S
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1
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| 1 |
IC50 = 700 nM
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CP0431409
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N-[7-methoxy-4-[[1-(pyridin-3-ylmethyl)indol-5-yl]amino]quinazolin-6-yl]propanamide
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C26H24N6O2
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1
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| 1 |
IC50 = 714 nM
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CP0445491
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(3-nitrophenyl)prop-2-enamide
Show/Hide
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C32H29ClN8O5
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3
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| 1 |
IC50 = 720 nM
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| 2 |
IC50 = 1800 nM
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| 3 |
IC50 > 10000 nM
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CP0332245
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4-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]-N-methylpyridine-2-carboxamide
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C26H22FN7O3
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1
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| 1 |
IC50 = 737 nM
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CP0432971
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N-[7-methoxy-4-[4-(2-phenylethyl)anilino]quinazolin-6-yl]propanamide
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C26H26N4O2
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1
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| 1 |
IC50 = 747 nM
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CP0521413
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4-(Bis(2-chloroethyl)amino)-N-(4-isopropylphenyl)benzamide
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C20H24Cl2N2O
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1
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| 1 |
IC50 = 750 nM
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CP0093667
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N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylpropanamide
Show/Hide
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C28H33ClN6O3
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3
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| 1 |
IC50 = 770 nM
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| 2 |
IC50 = 2000 nM
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| 3 |
IC50 > 10000 nM
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CP0531585
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3-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]phenol
Show/Hide
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C28H19FN4O
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1
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| 1 |
IC50 = 782 nM
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CP0571886
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N-(3-bromo-5-chloro-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
Show/Hide
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C16H10BrClFN3O2
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1
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| 1 |
IC50 = 782.8 nM
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CP0381870
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-4-methylpent-2-enamide
Show/Hide
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C29H32ClN7O3
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3
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| 1 |
IC50 = 800 nM
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| 2 |
IC50 = 1200 nM
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| 3 |
IC50 > 10000 nM
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CP0415673
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5-chloro-N-(1-hydroxy-3-phenylpropan-2-yl)-1H-indole-2-carboxamide
Show/Hide
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C18H17ClN2O2
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1
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| 1 |
IC50 = 800 nM
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CP0554327
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(2S)-2-[[5-(3-nitrophenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino]-2-phenylethanol
Show/Hide
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C26H20N4O4
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1
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| 1 |
IC50 = 820 nM
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CP0506140
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3-(3,4-Dimethylphenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C18H18FN3S
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1
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| 1 |
IC50 = 830 nM
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CP0281973
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-cyclopropylprop-2-enamide
Show/Hide
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C28H31ClN6O3
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3
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| 1 |
IC50 = 830 nM
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| 2 |
IC50 = 2800 nM
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| 3 |
IC50 = 5600 nM
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CP0380018
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(E)-4-(4-methylpiperazin-1-yl)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Show/Hide
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C28H30N8O
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1
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| 1 |
IC50 = 857 nM
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CP0376571
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1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
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C21H18Br2N2O2S
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1
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| 1 |
IC50 = 870 nM
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CP0441333
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4-[[[4-(3-bromoanilino)quinazolin-6-yl]amino]methyl]phenol
Show/Hide
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C21H17BrN4O
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1
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| 1 |
IC50 = 870 nM
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CP0068199
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9-(1-methylpyrazol-4-yl)-1-(1-prop-2-enoyl-2,3-dihydroindol-6-yl)benzo[h][1,6]naphthyridin-2-one
Show/Hide
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C27H21N5O2
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1
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| 1 |
IC50 = 874 nM
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CP0464950
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N-[4-[4-(3-fluorophenoxy)anilino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
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C24H21FN4O3
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1
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| 1 |
IC50 = 881 nM
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CP0385951
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N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine (15a)
Show/Hide
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C19H22N8O3
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3
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| 1 |
IC50 = 900 nM
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| 2 |
IC50 = 1800 nM
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| 3 |
IC50 > 10000 nM
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CP0416921
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N-[3-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
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C17H16N6O2
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3
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| 1 |
IC50 = 900 nM
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| 2 |
IC50 = 1800 nM
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| 3 |
IC50 > 10000 nM
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CP0543350
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3-ethyl-N-(1-hydroxy-3-phenylpropan-2-yl)-5-(trifluoromethyl)-1H-indole-2-carboxamide
Show/Hide
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C21H21F3N2O2
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1
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| 1 |
IC50 = 900 nM
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CP0526479
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ethyl 2-amino-4-[5-chloro-3-methyl-1-(4-methylphenyl)pyrazol-4-yl]-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
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C28H28ClN5O3
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1
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| 1 |
IC50 = 910 nM
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CP0520439
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4-(Bis(2-chloroethyl)amino)-N-(4-bromophenyl)benzamide
Show/Hide
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C17H17BrCl2N2O
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1
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| 1 |
IC50 = 940 nM
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CP0531039
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(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-(2-nitrophenyl)prop-2-enamide
Show/Hide
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C23H16ClN5O3
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1
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| 1 |
IC50 = 940 nM
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CP0469806
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(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-cyanophenyl)prop-2-enamide
Show/Hide
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C33H29ClN8O3
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3
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| 1 |
IC50 = 940 nM
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| 2 |
IC50 = 1800 nM
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| 3 |
IC50 > 10000 nM
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CP0540893
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3-[4-(4-fluorophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]propan-1-ol
Show/Hide
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C19H17FN4O
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1
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| 1 |
IC50 = 943 nM
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CP0446377
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1-benzyl-N-[6-(ethoxymethyl)-5-ethylpyrrolo[1,2-a][1,2,4]triazin-4-yl]-1H-indazol-5-amine
Show/Hide
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C25H26N6O
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1
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| 1 |
IC50 = 950 nM
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CP0456528
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ethyl 4-[(1-benzylindazol-5-yl)amino]-5-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
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C26H26N6O2
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1
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| 1 |
IC50 = 950 nM
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CP0415407
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1-(5-Chloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
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C21H19ClN2O3
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1
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| 1 |
IC50 = 960 nM
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CP0859405
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2-(2-(5-Fluoro-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
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C10H8FN3O2S
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1
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| 1 |
IC50 = 970 nM
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CP0429957
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1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
Show/Hide
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C21H18BrFN2OS
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1
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| 1 |
IC50 = 980 nM
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CP0497055
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tetradecyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
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C31H40O6
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1
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| 1 |
IC50 = 1010 nM
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CP0531038
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(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(2-nitrophenyl)prop-2-enamide
Show/Hide
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C23H16BrN5O3
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1
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| 1 |
IC50 = 1020 nM
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CP0541427
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ethyl 2-amino-4-[5-chloro-1-(4-chlorophenyl)-3-methylpyrazol-4-yl]-7,7-dimethyl-5-oxo-1-pyridin-3-yl-6,8-dihydro-4H-quinoline-3-carboxylate
Show/Hide
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C29H29Cl2N5O3
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1
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| 1 |
IC50 = 1030 nM
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CP0489670
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1-(5-Bromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
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C21H19BrN2O3
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1
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| 1 |
IC50 = 1070 nM
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CP0847129
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2-(5-Phenyl-3-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C19H17N3OS
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1
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| 1 |
IC50 = 1080 nM
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CP0483470
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2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}acetamide
Show/Hide
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C24H23N7O
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1
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| 1 |
IC50 = 1100 nM
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CP0543150
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methyl 2-amino-5-oxo-1-pyridin-3-yl-4-(tetrazolo[1,5-a]quinolin-4-yl)-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
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C25H21N7O3
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1
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| 1 |
IC50 = 1100 nM
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CP0428426
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N-[2-[4-(1H-pyrazol-5-ylamino)quinazolin-2-yl]phenyl]prop-2-enamide
Show/Hide
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C20H16N6O
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3
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| 1 |
IC50 = 1100 nM
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| 2 |
IC50 = 2700 nM
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| 3 |
IC50 > 10000 nM
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CP0309076
|
(2E,6E)-4-methyl-2,6-bis[(3,5,6-trimethylpyrazin-2-yl)methylidene]cyclohexan-1-one
Show/Hide
|
C23H28N4O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0176037
|
1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C21H18Br2N2O3
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0847122
|
2-(3,5-Dip-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C20H19N3OS
|
1
|
| 1 |
IC50 = 1160 nM
|
|
|
|
CP0397172
|
2-chloro-N-(4-chlorophenyl)sulfonyl-6-methylpyridine-3-carboxamide
Show/Hide
|
C13H10Cl2N2O3S
|
1
|
| 1 |
IC50 = 1190 nM
|
|
|
|
CP0449635
|
(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-cyclopentylprop-2-enamide
Show/Hide
|
C31H34ClN7O3
|
3
|
| 1 |
IC50 = 1200 nM
|
|
|
| 2 |
IC50 = 2200 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0479437
|
(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-(4-nitrophenyl)prop-2-enamide
Show/Hide
|
C32H29ClN8O5
|
3
|
| 1 |
IC50 = 1200 nM
|
|
|
| 2 |
IC50 = 2300 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0552315
|
N-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]phenyl]thieno[2,3-b]quinoline-2-carboxamide
Show/Hide
|
C30H24N2O5S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0452396
|
(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-chlorophenyl)prop-2-enamide
Show/Hide
|
C23H16BrClN4O
|
1
|
| 1 |
IC50 = 1210 nM
|
|
|
|
CP0880338
|
2-(2-(3,5-Dibromo-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H7Br2N3O2S
|
1
|
| 1 |
IC50 = 1240 nM
|
|
|
|
CP0847109
|
2-(5-(4-Bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16BrN3O2S
|
1
|
| 1 |
IC50 = 1260 nM
|
|
|
|
CP0415101
|
N-dodecyl-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
Show/Hide
|
C29H37NO5
|
1
|
| 1 |
IC50 = 1270 nM
|
|
|
|
CP0514949
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-(benzyloxy)phenyl)acrylate
Show/Hide
|
C22H21N3O5
|
1
|
| 1 |
IC50 = 1270 nM
|
|
|
|
CP0481743
|
methyl 2-amino-4-(7-methoxytetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C26H23N7O4
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0440594
|
2-[5-(3,4-dimethylphenyl)-3-naphthalen-1-yl-3,4-dihydropyrazol-2-yl]-1,3-thiazol-4-one
Show/Hide
|
C24H21N3OS
|
1
|
| 1 |
IC50 = 1320 nM
|
|
|
|
CP0491206
|
1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
Show/Hide
|
C21H17Cl2FN2OS
|
1
|
| 1 |
IC50 = 1340 nM
|
|
|
|
CP0504824
|
2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-icosylacetamide
Show/Hide
|
C37H53NO5
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0847124
|
2-(5-(4-Bromophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14BrN3OS
|
1
|
| 1 |
IC50 = 1350 nM
|
|
|
|
CP0522071
|
5-(4-Chlorophenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C18H18ClN3S
|
1
|
| 1 |
IC50 = 1360 nM
|
|
|
|
CP0485631
|
N-[1-(4-hydroxycyclohexyl)-4-methylbenzimidazol-2-yl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H22F3N3O2
|
3
|
| 1 |
IC50 = 1370 nM
|
|
|
| 2 |
IC50 = 11750 nM
|
|
|
| 3 |
IC50 > 50000 nM
|
|
|
|
CP0401567
|
2-(4-Aminophenoxy)-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine (15k)
Show/Hide
|
C19H24N8O
|
3
|
| 1 |
IC50 = 1400 nM
|
|
|
| 2 |
IC50 = 2100 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0493873
|
6-methoxy-N-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]phenyl]thieno[2,3-b]quinoline-2-carboxamide
Show/Hide
|
C31H26N2O6S
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0359026
|
4-[4-(4-fluorophenyl)-2-phenyl-1H-imidazol-5-yl]-2-phenyl-1H-pyrrolo[2,3-b]pyridine
Show/Hide
|
C28H19FN4
|
1
|
| 1 |
IC50 = 1430 nM
|
|
|
|
CP0373905
|
(E)-2-((E)-(3,5-Dichloro-2-hydroxybenzylidene)hydrazono)thiazolidin-4-one (5)
Show/Hide
|
C10H7Cl2N3O2S
|
1
|
| 1 |
IC50 = 1460 nM
|
|
|
|
CP0383873
|
4-(Bis(2-chloroethyl)amino)-N-(4-chlorophenyl)benzamide
Show/Hide
|
C17H17Cl3N2O
|
1
|
| 1 |
IC50 = 1490 nM
|
|
|
|
CP0114130
|
(2E,6E)-2-[(2-chlorophenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H21ClO3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0549692
|
6-N-[(5-bromothiophen-2-yl)methyl]-4-N-(3-chlorophenyl)quinazoline-4,6-diamine
Show/Hide
|
C19H14BrClN4S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0385833
|
(E)-4,4,4-trifluoro-N-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]but-2-enamide
Show/Hide
|
C23H25F3N8O2
|
3
|
| 1 |
IC50 = 1500 nM
|
|
|
| 2 |
IC50 = 2000 nM
|
|
|
| 3 |
IC50 = 2100 nM
|
|
|
|
CP0370065
|
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
Show/Hide
|
C17H12ClN3OS
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0523768
|
2-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)aniline
Show/Hide
|
C15H13N3OS
|
1
|
| 1 |
IC50 = 1510 nM
|
|
|
|
CP0919938
|
(Z)-2-((E)-3-(4-nitrophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14N4O2S
|
1
|
| 1 |
IC50 = 1570 nM
|
|
|
|
CP0414891
|
2-(2-methyl-5-nitroimidazol-1-yl)-N-[(E)-(6-methyl-2-phenoxyquinolin-3-yl)methylideneamino]acetamide
Show/Hide
|
C23H20N6O4
|
2
|
| 1 |
IC50 = 1580 nM
|
|
|
| 2 |
IC50 = 3170 nM
|
|
|
|
CP0517556
|
icosyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
|
C37H52O6
|
1
|
| 1 |
IC50 = 1589 nM
|
|
|
|
CP0439402
|
2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}acetic acid
Show/Hide
|
C24H22N6O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0415058
|
(2E,6E)-2-benzylidene-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H22O3
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0494743
|
N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-(2-nitrophenoxy)pyrimidin-4-amine (13)
Show/Hide
|
C19H22N8O3
|
3
|
| 1 |
IC50 = 1600 nM
|
|
|
| 2 |
IC50 = 1900 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0493874
|
N-[4-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]phenyl]thieno[2,3-b]quinoline-2-carboxamide
Show/Hide
|
C29H22N2O4S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0526874
|
4-N-(3-bromophenyl)-6-N-[(4-chlorophenyl)methyl]quinazoline-4,6-diamine
Show/Hide
|
C21H16BrClN4
|
1
|
| 1 |
IC50 = 1640 nM
|
|
|
|
CP0847108
|
2-(5-(4-Chlorophenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16ClN3OS
|
1
|
| 1 |
IC50 = 1660 nM
|
|
|
|
CP0380595
|
(E)-4-(dimethylamino)-N-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]but-2-enamide
Show/Hide
|
C25H33N9O2
|
3
|
| 1 |
IC50 = 1700 nM
|
|
|
| 2 |
IC50 = 1800 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0123972
|
3-benzyl-8-chloro-10-methyl-2H-pyrazino[1,2-a]indol-1-one
Show/Hide
|
C19H15ClN2O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0541522
|
5-(4-chlorophenyl)-2-(3,4,5-trimethoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
Show/Hide
|
C19H16ClN3O3S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0913242
|
2-(2-(4-Bromobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8BrN3OS
|
1
|
| 1 |
IC50 = 1720 nM
|
|
|
|
CP0498688
|
4-(Bis(2-chloroethyl)amino)-N-(4-fluorophenyl)benzamide
Show/Hide
|
C17H17Cl2FN2O
|
1
|
| 1 |
IC50 = 1720 nM
|
|
|
|
CP0497054
|
dodecyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
|
C29H36O6
|
1
|
| 1 |
IC50 = 1720 nM
|
|
|
|
CP0491207
|
1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
Show/Hide
|
C21H17Br2FN2OS
|
1
|
| 1 |
IC50 = 1760 nM
|
|
|
|
CP0401565
|
N-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
|
C22H26N8O2
|
3
|
| 1 |
IC50 = 1800 nM
|
|
|
| 2 |
IC50 = 2400 nM
|
|
|
| 3 |
IC50 = 3100 nM
|
|
|
|
CP0447436
|
1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C21H18Cl2N2O3
|
1
|
| 1 |
IC50 = 1860 nM
|
|
|
|
CP0452142
|
4-[[[4-(3-chloroanilino)quinazolin-6-yl]amino]methyl]phenol
Show/Hide
|
C21H17ClN4O
|
1
|
| 1 |
IC50 = 1870 nM
|
|
|
|
CP0906594
|
(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)-2-aminobenzohydrazide
Show/Hide
|
C19H17BrN6O3
|
1
|
| 1 |
IC50 = 1890 nM
|
|
|
|
CP0445303
|
(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(4-methylsulfonylphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C23H24O5S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0095684
|
N-(3-((4-((5-Methyl-1H-pyrazol-3-yl)amino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl)oxy)phenyl)propionamide (23)
Show/Hide
|
C22H28N8O2
|
2
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0193029
|
N-[2-phenyl-4-(1H-pyrazol-5-ylamino)quinazolin-7-yl]prop-2-enamide
Show/Hide
|
C20H16N6O
|
3
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
IC50 = 2200 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0456048
|
N-[3-[4-(4-methylpiperazin-1-yl)-6-(1H-pyrazol-5-ylamino)pyrimidin-2-yl]oxyphenyl]prop-2-enamide
Show/Hide
|
C21H24N8O2
|
3
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
IC50 = 2000 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0543062
|
(2E,6E)-2-[(2-bromo-4,5-dimethoxyphenyl)methylidene]-4-methyl-6-[(3,5,6-trimethylpyrazin-2-yl)methylidene]cyclohexan-1-one
Show/Hide
|
C24H27BrN2O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0859406
|
2-(2-(4-Chlorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8ClN3OS
|
1
|
| 1 |
IC50 = 1940 nM
|
|
|
|
CP0440140
|
1-(5-Chloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H18ClFN2O2
|
1
|
| 1 |
IC50 = 1980 nM
|
|
|
|
CP0080480
|
(2E,6E)-2,6-bis[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C24H26O5
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0897862
|
2-(5-(4-Fluorophenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16FN3OS
|
1
|
| 1 |
IC50 = 2010 nM
|
|
|
|
CP0910691
|
2-(3,5-Bis(4-bromophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13Br2N3OS
|
1
|
| 1 |
IC50 = 2030 nM
|
|
|
|
CP0915458
|
(Z)-2-((E)-3-(3-fluorophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14FN3S
|
1
|
| 1 |
IC50 = 2080 nM
|
|
|
|
CP0499485
|
5-bromo-N-(4-bromophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H8Br2N2O3S
|
1
|
| 1 |
IC50 = 2080 nM
|
|
|
|
CP0411221
|
ethyl 2-amino-4-(5-chloro-3-methyl-1-phenylpyrazol-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C27H26ClN5O3
|
1
|
| 1 |
IC50 = 2090 nM
|
|
|
|
CP0359710
|
(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(2-fluorophenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H21FO3
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0198892
|
N-[2-phenyl-4-(1H-pyrazol-5-ylamino)quinazolin-7-yl]propanamide
Show/Hide
|
C20H18N6O
|
3
|
| 1 |
IC50 = 2100 nM
|
|
|
| 2 |
IC50 = 2200 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0541957
|
N-decyl-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
Show/Hide
|
C27H33NO5
|
1
|
| 1 |
IC50 = 2140 nM
|
|
|
|
CP0486887
|
5-(4-Bromophenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C18H18BrN3S
|
1
|
| 1 |
IC50 = 2170 nM
|
|
|
|
CP0939808
|
(Z)-2-((E)-1-(4-bromophenyl)-3-(4-fluorophenyl)allylidene)hydrazinecarbothioamide
Show/Hide
|
C16H13BrFN3S
|
1
|
| 1 |
IC50 = 2170 nM
|
|
|
|
CP0845353
|
2-(2-(4-Fluorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8FN3OS
|
1
|
| 1 |
IC50 = 2180 nM
|
|
|
|
CP0122440
|
(2E,6E)-2-[(3-chlorophenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H21ClO3
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0400614
|
(Z)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-[4-(dimethylamino)phenyl]-2-(trifluoromethyl)prop-2-enamide
Show/Hide
|
C34H35ClF3N7O3
|
3
|
| 1 |
IC50 = 2200 nM
|
|
|
| 2 |
IC50 = 6300 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0539409
|
1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H18BrFN2O2
|
1
|
| 1 |
IC50 = 2240 nM
|
|
|
|
CP0847120
|
2-(5-(4-Bromophenyl)-3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13BrClN3OS
|
1
|
| 1 |
IC50 = 2280 nM
|
|
|
|
CP0853322
|
2-(3-(4-Methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H17N3O2S
|
1
|
| 1 |
IC50 = 2370 nM
|
|
|
|
CP0939806
|
(Z)-2-((E)-1,3-diphenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H15N3S
|
1
|
| 1 |
IC50 = 2380 nM
|
|
|
|
CP0403747
|
(E)-3-(5-bromothiophen-2-yl)-N-[4-(3-chloroanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C21H14BrClN4OS
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0866476
|
4-Methyl-2,6-bis-(3,5,6-trimethyl-pyrazin-2-ylmethylene)-cyclohexanone oxime
Show/Hide
|
C23H29N5O
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0248934
|
3-benzyl-8-chloro-2H-pyrazino[1,2-a]indol-1-one
Show/Hide
|
C18H13ClN2O
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0385950
|
N-[3-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]phenyl]prop-2-enamide
Show/Hide
|
C17H16N6O
|
3
|
| 1 |
IC50 = 2500 nM
|
|
|
| 2 |
IC50 = 2800 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0537256
|
(3E,5E)-1-propan-2-yl-3,5-bis[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-one
Show/Hide
|
C24H31N5O
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0956837
|
(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)-2-hydroxybenzohydrazide
Show/Hide
|
C19H16BrN5O4
|
1
|
| 1 |
IC50 = 2580 nM
|
|
|
|
CP0508916
|
N-(4-bromophenyl)sulfonyl-2-chloro-6-methylpyridine-3-carboxamide
Show/Hide
|
C13H10BrClN2O3S
|
1
|
| 1 |
IC50 = 2640 nM
|
|
|
|
CP0566941
|
2-[5-(4-methoxyphenyl)-3-naphthalen-2-yl-3,4-dihydropyrazol-2-yl]-1,3-thiazol-4-one
Show/Hide
|
C23H19N3O2S
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0569759
|
5-phenyl-2-(3,4,5-trimethoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
Show/Hide
|
C19H17N3O3S
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0484796
|
6-methoxy-N-[4-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]phenyl]thieno[2,3-b]quinoline-2-carboxamide
Show/Hide
|
C29H22N2O4S
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0490281
|
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-naphthalen-1-ylprop-2-enamide
Show/Hide
|
C27H19ClN4O
|
1
|
| 1 |
IC50 = 2810 nM
|
|
|
|
CP0361808
|
(NE)-N-[(2E,6E)-2-[(2-bromo-4,5-dimethoxyphenyl)methylidene]-4-methyl-6-[(3,5,6-trimethylpyrazin-2-yl)methylidene]cyclohexylidene]hydroxylamine
Show/Hide
|
C24H28BrN3O3
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0552316
|
N-[4-[(E)-3-(3-methoxyphenyl)prop-2-enoyl]phenyl]-6-methylthieno[2,3-b]quinoline-2-carboxamide
Show/Hide
|
C29H22N2O3S
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0427116
|
5,6-diphenyl-N-[(1R)-1-phenylethyl]furo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C26H21N3O
|
1
|
| 1 |
IC50 = 2991 nM
|
|
|
|
CP0910690
|
2-(3-Phenyl-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H17N3OS
|
1
|
| 1 |
IC50 = 3030 nM
|
|
|
|
CP0514554
|
3-(3,4-Dimethylphenyl)-5-(4-nitrophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C18H18N4O2S
|
1
|
| 1 |
IC50 = 3060 nM
|
|
|
|
CP0506648
|
(3E,5E)-3-[(2-chloro-4,5-dimethoxyphenyl)methylidene]-1-propan-2-yl-5-[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-one
Show/Hide
|
C25H30ClN3O3
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0497053
|
decyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
|
C27H32O6
|
1
|
| 1 |
IC50 = 3110 nM
|
|
|
|
CP0526875
|
4-N-(3-bromophenyl)-6-N-[(4-bromophenyl)methyl]quinazoline-4,6-diamine
Show/Hide
|
C21H16Br2N4
|
1
|
| 1 |
IC50 = 3130 nM
|
|
|
|
CP0878673
|
2-(3-(4-Bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14BrN3OS
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0455168
|
6-methyl-N-[4-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]phenyl]thieno[2,3-b]quinoline-2-carboxamide
Show/Hide
|
C31H26N2O5S
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0463542
|
2-[[[4-(3-bromoanilino)quinazolin-6-yl]amino]methyl]phenol
Show/Hide
|
C21H17BrN4O
|
1
|
| 1 |
IC50 = 3220 nM
|
|
|
|
CP0428346
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-bromophenyl)acrylate
Show/Hide
|
C15H14BrN3O4
|
1
|
| 1 |
IC50 = 3240 nM
|
|
|
|
CP0411010
|
2-[5-(4-methylphenyl)-3-naphthalen-2-yl-3,4-dihydropyrazol-2-yl]-1,3-thiazol-4-one
Show/Hide
|
C23H19N3OS
|
1
|
| 1 |
IC50 = 3250 nM
|
|
|
|
CP0853155
|
2-(2-(4-Methylbenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C11H11N3OS
|
1
|
| 1 |
IC50 = 3260 nM
|
|
|
|
CP0418411
|
5-bromo-N-(4-fluorophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H8BrFN2O3S
|
1
|
| 1 |
IC50 = 3270 nM
|
|
|
|
CP0848283
|
2-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H15N3OS
|
1
|
| 1 |
IC50 = 3380 nM
|
|
|
|
CP0549693
|
4-N-(3-chlorophenyl)-6-N-(thiophen-2-ylmethyl)quinazoline-4,6-diamine
Show/Hide
|
C19H15ClN4S
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0478753
|
N-[2-phenyl-6-(1H-pyrazol-5-ylamino)pyrimidin-4-yl]propanamide
Show/Hide
|
C16H16N6O
|
2
|
| 1 |
IC50 = 3400 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0568876
|
1-[6-[[2-[(3S,4R)-3-fluoro-4-hydroxy-3-methylpiperidin-1-yl]pyrimidin-4-yl]amino]-4-propan-2-yl-2,7-naphthyridin-1-yl]azetidine-3-carbonitrile
Show/Hide
|
C25H29FN8O
|
1
|
| 1 |
IC50 = 3401 nM
|
|
|
|
CP0502534
|
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-(4-nitrophenyl)prop-2-enamide
Show/Hide
|
C23H16ClN5O3
|
1
|
| 1 |
IC50 = 3450 nM
|
|
|
|
CP0429966
|
1-(2-Hydroxy-5-methylbenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C22H22N2O2S
|
1
|
| 1 |
IC50 = 3460 nM
|
|
|
|
CP0532333
|
(E)-3-(4-bromophenyl)-N-[4-(3-chloroanilino)quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C23H16BrClN4O
|
1
|
| 1 |
IC50 = 3490 nM
|
|
|
|
CP0868127
|
2-(5-(4-Chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14ClN3OS
|
1
|
| 1 |
IC50 = 3490 nM
|
|
|
|
CP0503182
|
2-[[[4-(3-chloroanilino)quinazolin-6-yl]amino]methyl]phenol
Show/Hide
|
C21H17ClN4O
|
1
|
| 1 |
IC50 = 3540 nM
|
|
|
|
CP0541956
|
2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-nonylacetamide
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
IC50 = 3580 nM
|
|
|
|
CP0380378
|
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-(2-chloropyridin-3-yl)prop-2-enamide
Show/Hide
|
C22H15Cl2N5O
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0532332
|
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-phenylprop-2-enamide
Show/Hide
|
C23H17ClN4O
|
1
|
| 1 |
IC50 = 3610 nM
|
|
|
|
CP0411851
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-chlorophenyl)acrylate
Show/Hide
|
C15H14ClN3O4
|
1
|
| 1 |
IC50 = 3620 nM
|
|
|
|
CP0917266
|
(Z)-2-((E)-3-(3-nitrophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14N4O2S
|
1
|
| 1 |
IC50 = 3740 nM
|
|
|
|
CP0400284
|
5-(2-Chlorophenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C18H18ClN3S
|
1
|
| 1 |
IC50 = 3870 nM
|
|
|
|
CP0411850
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(naphthalen-1-yl)acrylate
Show/Hide
|
C19H17N3O4
|
1
|
| 1 |
IC50 = 3880 nM
|
|
|
|
CP0102932
|
(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[[4-(dimethylamino)phenyl]methylidene]cyclohexan-1-one
Show/Hide
|
C24H27NO3
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0361807
|
N-[(3E,5E)-1-propan-2-yl-3,5-bis[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-ylidene]hydroxylamine
Show/Hide
|
C24H32N6O
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0189379
|
3-benzyl-10-ethyl-8-(trifluoromethyl)-2H-pyrazino[1,2-a]indol-1-one
Show/Hide
|
C21H17F3N2O
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0499495
|
2-[5-(3,4-dimethylphenyl)-3-naphthalen-1-yl-3,4-dihydropyrazol-2-yl]-4-phenyl-4,5-dihydro-1,3-thiazole
Show/Hide
|
C30H27N3S
|
1
|
| 1 |
IC50 = 3960 nM
|
|
|
|
CP0449760
|
6-N-[(6-bromopyridin-2-yl)methyl]-4-N-(3-chlorophenyl)quinazoline-4,6-diamine
Show/Hide
|
C20H15BrClN5
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0395480
|
N-[(E)-[2-(4-chlorophenoxy)quinolin-3-yl]methylideneamino]-2-(2-methyl-5-nitroimidazol-1-yl)acetamide
Show/Hide
|
C22H17ClN6O4
|
2
|
| 1 |
IC50 = 4100 nM
|
|
|
| 2 |
IC50 = 5120 nM
|
|
|
|
CP0427703
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-fluorophenyl)acrylate
Show/Hide
|
C15H14FN3O4
|
1
|
| 1 |
IC50 = 4120 nM
|
|
|
|
CP0878674
|
2-(3-(4-Bromophenyl)-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13BrClN3OS
|
1
|
| 1 |
IC50 = 4120 nM
|
|
|
|
CP0401471
|
1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H17Cl2FN2O2
|
1
|
| 1 |
IC50 = 4150 nM
|
|
|
|
CP0510446
|
2-amino-4-[5-chloro-1-(4-chlorophenyl)-3-methylpyrazol-4-yl]-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C25H20Cl2N6O
|
1
|
| 1 |
IC50 = 4150 nM
|
|
|
|
CP0471051
|
5-(2-Bromophenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C18H18BrN3S
|
1
|
| 1 |
IC50 = 4210 nM
|
|
|
|
CP0897863
|
2-(5-(4-Methoxyphenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C20H19N3O2S
|
1
|
| 1 |
IC50 = 4240 nM
|
|
|
|
CP0847125
|
2-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H17N3O2S
|
1
|
| 1 |
IC50 = 4270 nM
|
|
|
|
CP0468346
|
(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(2-bromophenyl)prop-2-enamide
Show/Hide
|
C23H16Br2N4O
|
1
|
| 1 |
IC50 = 4280 nM
|
|
|
|
CP0509090
|
methyl 2-amino-4-(7-methyltetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C26H23N7O3
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0483980
|
6-(dimethylamino)-N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]hexanamide
Show/Hide
|
C34H37N5O3
|
1
|
| 1 |
IC50 = 4327 nM
|
|
|
|
CP0427649
|
4-N-(3-chlorophenyl)-6-N-[(4-chlorophenyl)methyl]quinazoline-4,6-diamine
Show/Hide
|
C21H16Cl2N4
|
1
|
| 1 |
IC50 = 4410 nM
|
|
|
|
CP0510952
|
(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(4-hydroxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H22O4
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0520466
|
1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H17Br2FN2O2
|
1
|
| 1 |
IC50 = 4680 nM
|
|
|
|
CP0524064
|
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-pyridin-3-ylprop-2-enamide
Show/Hide
|
C22H16ClN5O
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0885035
|
2-(2-(4-Hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H9N3O2S
|
1
|
| 1 |
IC50 = 4710 nM
|
|
|
|
CP0921415
|
2-(5-(4-Bromophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13BrFN3OS
|
1
|
| 1 |
IC50 = 4790 nM
|
|
|
|
CP0235900
|
(2E,6E)-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C30H38O4
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0460317
|
2-amino-5-oxo-1-pyridin-3-yl-4-(tetrazolo[1,5-a]quinolin-4-yl)-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C24H18N8O
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0921414
|
2-(5-(4-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14FN3OS
|
1
|
| 1 |
IC50 = 4860 nM
|
|
|
|
CP0401566
|
2-(3-aminophenoxy)-6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine
Show/Hide
|
C19H24N8O
|
2
|
| 1 |
IC50 = 4900 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0453227
|
N-[3-[4-(1H-indazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]phenyl]prop-2-enamide
Show/Hide
|
C25H26N8O
|
3
|
| 1 |
IC50 = 4900 nM
|
|
|
| 2 |
IC50 = 5000 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0361809
|
(NE)-N-[(3E,5E)-3-[(2-bromo-4,5-dimethoxyphenyl)methylidene]-1-propan-2-yl-5-[(3,5,6-trimethylpyrazin-2-yl)methylidene]piperidin-4-ylidene]hydroxylamine
Show/Hide
|
C25H31BrN4O3
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0423570
|
nonyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
|
C26H30O6
|
1
|
| 1 |
IC50 = 4960 nM
|
|
|
|
CP0524148
|
4-N-(3-chlorophenyl)-6-N-(3-methylsulfanylpropyl)quinazoline-4,6-diamine
Show/Hide
|
C18H19ClN4S
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0919216
|
(Z)-2-((E)-3-(biphenyl-4-yl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C22H19N3S
|
1
|
| 1 |
IC50 = 5110 nM
|
|
|
|
CP0495971
|
2-benzylsulfanyl-5-(2-fluorophenyl)-1,3,4-oxadiazole
Show/Hide
|
C15H11FN2OS
|
1
|
| 1 |
IC50 = 5110 nM
|
|
|
|
CP0521758
|
(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-nitrophenyl)prop-2-enamide
Show/Hide
|
C23H16BrN5O3
|
1
|
| 1 |
IC50 = 5160 nM
|
|
|
|
CP0184868
|
(E)-N-(2-methoxyphenyl)-3-phenylprop-2-enamide
Show/Hide
|
C16H15NO2
|
1
|
| 1 |
IC50 = 5160 nM
|
|
|
|
CP0388316
|
3-(3,4-Dimethylphenyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C18H18FN3S
|
1
|
| 1 |
IC50 = 5190 nM
|
|
|
|
CP0521301
|
2-[5-(4-methylphenyl)-3-naphthalen-2-yl-3,4-dihydropyrazol-2-yl]-4-phenyl-4,5-dihydro-1,3-thiazole
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C29H25N3S
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1
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| 1 |
IC50 = 5260 nM
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CP0233300
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3-(3,4-Dichlorophenyl)-5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
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C16H13Cl2N3OS
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1
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| 1 |
IC50 = 5270 nM
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CP0450491
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(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(3-hydroxy-4-methoxyphenyl)methylidene]cyclohexan-1-one
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C23H24O5
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1
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| 1 |
IC50 = 5300 nM
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CP0541955
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2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxy-N-octylacetamide
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C25H29NO5
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1
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| 1 |
IC50 = 5330 nM
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CP0899898
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2-(3-(4-Chlorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C18H14ClN3OS
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1
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| 1 |
IC50 = 5340 nM
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CP0885544
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2-(5-(4-Chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C19H16ClN3O2S
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1
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| 1 |
IC50 = 5350 nM
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CP0379898
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2-amino-4-(7-methoxytetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
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C25H20N8O2
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1
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| 1 |
IC50 = 5400 nM
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CP0853520
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2-(3-(4-Methoxyphenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C20H19N3O2S
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1
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| 1 |
IC50 = 5460 nM
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CP0556670
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2-[5-(4-methoxyphenyl)-3-naphthalen-1-yl-3,4-dihydropyrazol-2-yl]-1,3-thiazol-4-one
Show/Hide
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C23H19N3O2S
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1
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| 1 |
IC50 = 5530 nM
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CP0918021
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2-(3-(4-bromophenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C19H16BrN3OS
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1
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| 1 |
IC50 = 5580 nM
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CP0235897
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(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(4-fluorophenyl)methylidene]cyclohexan-1-one
Show/Hide
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C22H21FO3
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1
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| 1 |
IC50 = 5600 nM
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CP0558747
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2-(4-methoxyphenyl)-5-phenyl-[1,3]thiazolo[3,2-b][1,2,4]triazole
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C17H13N3OS
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1
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| 1 |
IC50 = 5600 nM
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CP0500084
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6-N-[(4-bromophenyl)methyl]-4-N-(3-chlorophenyl)quinazoline-4,6-diamine
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C21H16BrClN4
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1
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| 1 |
IC50 = 5670 nM
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CP0297599
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2-benzylsulfanyl-5-(2-methylphenyl)-1,3,4-oxadiazole
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C16H14N2OS
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1
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| 1 |
IC50 = 5720 nM
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CP0471050
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3-(3,4-Dichlorophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C17H15Cl2N3OS
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1
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| 1 |
IC50 = 5740 nM
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CP0418466
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(naphthalen-2-yl)acrylate
Show/Hide
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C19H17N3O4
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1
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| 1 |
IC50 = 5760 nM
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CP0859407
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2-(2-(4-Methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one
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C11H11N3O2S
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1
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| 1 |
IC50 = 5780 nM
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CP0406247
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1-(2-Hydroxy-3,5-dimethylbenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
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C23H24N2O2S
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1
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| 1 |
IC50 = 5830 nM
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CP0500227
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octyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
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C25H28O6
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1
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| 1 |
IC50 = 5840 nM
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CP0467528
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4-(dimethylamino)-N-[2-methyl-3-[1-methyl-5-[4-(morpholine-4-carbonyl)-3-(prop-2-enoylamino)anilino]-6-oxopyridin-3-yl]phenyl]benzamide
Show/Hide
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C36H38N6O5
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1
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| 1 |
IC50 = 5882 nM
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CP0860905
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2-(5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C19H16FN3O2S
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1
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| 1 |
IC50 = 5950 nM
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CP0396709
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(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(3-methoxyphenyl)prop-2-enamide
Show/Hide
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C24H19BrN4O2
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1
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| 1 |
IC50 = 6020 nM
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CP0235898
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(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(3-methoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
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C23H24O4
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1
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| 1 |
IC50 = 6100 nM
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CP0904565
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(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)-4-methylbenzohydrazide
Show/Hide
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C20H18BrN5O3
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1
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| 1 |
IC50 = 6130 nM
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CP0414497
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ethyl 2-amino-4-[5-chloro-1-(4-chlorophenyl)-3-methylpyrazol-4-yl]-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
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C27H25Cl2N5O3
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1
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| 1 |
IC50 = 6150 nM
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CP0418471
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3-(3,4-Dichlorophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C16H12Cl2FN3S
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1
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| 1 |
IC50 = 6270 nM
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CP0417835
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N-heptyl-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
Show/Hide
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C24H27NO5
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1
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| 1 |
IC50 = 6280 nM
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CP0400612
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(Z)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-fluorophenyl)-2-(trifluoromethyl)prop-2-enamide
Show/Hide
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C32H29ClF4N6O3
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2
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| 1 |
IC50 = 6300 nM
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| 2 |
IC50 > 10000 nM
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CP0411009
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2-(3-naphthalen-2-yl-5-phenyl-3,4-dihydropyrazol-2-yl)-1,3-thiazol-4-one
Show/Hide
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C22H17N3OS
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1
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| 1 |
IC50 = 6310 nM
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CP0493531
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5-(2-Bromophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C16H12BrCl2N3S
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1
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| 1 |
IC50 = 6430 nM
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CP0885543
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2-(3-(4-Bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C18H13BrFN3OS
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1
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| 1 |
IC50 = 6480 nM
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CP0471049
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3-(3,4-Dichlorophenyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C16H12Cl2FN3S
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1
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| 1 |
IC50 = 6560 nM
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CP0425415
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(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-(3-methoxyphenyl)prop-2-enamide
Show/Hide
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C24H19ClN4O2
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1
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| 1 |
IC50 = 6630 nM
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CP0878669
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2-(3-(4-Chlorophenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C19H16ClN3OS
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1
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| 1 |
IC50 = 6670 nM
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CP0220150
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(2E,6E)-2-[(3-bromophenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
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C22H21BrO3
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1
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| 1 |
IC50 = 6800 nM
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CP0906060
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N-(1-(3-Acrylamidocyclopentyl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
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C24H23F3N4O2
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2
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| 1 |
IC50 = 6810 nM
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| 2 |
IC50 > 50000 nM
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CP0447434
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(E)-2((E)-(4-Nitrobenzylidene)hydrazono)thiazolidine-4-one (2)
Show/Hide
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C10H8N4O3S
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1
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| 1 |
IC50 = 6820 nM
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CP0467438
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-isopropylphenyl)acrylate
Show/Hide
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C18H21N3O4
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1
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| 1 |
IC50 = 6820 nM
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CP0438774
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5-(4-Bromophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C16H12BrCl2N3S
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1
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| 1 |
IC50 = 6850 nM
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CP0447341
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N-[2-methyl-3-[1-methyl-5-[4-(morpholine-4-carbonyl)-3-(prop-2-enoylamino)anilino]-6-oxopyridin-3-yl]phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide
Show/Hide
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C36H37N5O5S
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1
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| 1 |
IC50 = 6863 nM
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CP0481744
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ethyl 2-amino-4-(7-methyltetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
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C27H25N7O3
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1
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| 1 |
IC50 = 7000 nM
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CP0445302
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(2E,6E)-2-[(4-bromophenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
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C22H21BrO3
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1
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| 1 |
IC50 = 7100 nM
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CP0541521
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5-(4-chlorophenyl)-2-phenyl-[1,3]thiazolo[3,2-b][1,2,4]triazole
Show/Hide
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C16H10ClN3S
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1
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| 1 |
IC50 = 7200 nM
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CP0509049
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(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(4-methoxyphenyl)prop-2-enamide
Show/Hide
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C24H19BrN4O2
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1
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| 1 |
IC50 = 7220 nM
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CP0510467
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heptyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
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C24H26O6
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1
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| 1 |
IC50 = 7230 nM
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CP0373870
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5-(2-Chlorophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C16H12Cl3N3S
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1
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| 1 |
IC50 = 7280 nM
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CP0436841
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5-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C16H12Cl3N3S
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1
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| 1 |
IC50 = 7320 nM
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CP0069190
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(E)-N-(2-fluorophenyl)-3-phenylprop-2-enamide
Show/Hide
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C15H12FNO
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1
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| 1 |
IC50 = 7370 nM
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CP0452147
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3-(3,4-Dichlorophenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C17H15Cl2N3S
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1
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| 1 |
IC50 = 7380 nM
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CP0436088
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1-benzyl-N-{5-ethyl-6-[(ethylamino)methyl]pyrrolo[1,2-a][1,2,4]triazin-4-yl}-1H-indazol-5-amine
Show/Hide
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C25H27N7
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1
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| 1 |
IC50 = 7400 nM
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CP0523767
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2-benzylsulfanyl-5-(4-tert-butylphenyl)-1,3,4-oxadiazole
Show/Hide
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C19H20N2OS
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1
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| 1 |
IC50 = 7440 nM
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CP0924341
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2-(2-(3-Bromobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
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C10H8BrN3OS
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1
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| 1 |
IC50 = 7460 nM
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CP0321235
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(2E,6E)-2-(cyclohexylmethylidene)-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
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C22H28O3
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1
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| 1 |
IC50 = 7500 nM
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CP0373847
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1-(2-Hydroxy-5-methylbenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
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C22H22N2O3
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1
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| 1 |
IC50 = 7510 nM
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CP0399844
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2-(2-methyl-5-nitroimidazol-1-yl)-N-[(E)-[2-(4-methylphenoxy)quinolin-3-yl]methylideneamino]acetamide
Show/Hide
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C23H20N6O4
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2
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| 1 |
IC50 = 7670 nM
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| 2 |
IC50 = 23130 nM
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CP0452398
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(E)-N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(2-methoxyphenyl)prop-2-enamide
Show/Hide
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C24H19BrN4O2
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1
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| 1 |
IC50 = 7710 nM
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CP0487084
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3-(3,4-Dichlorophenyl)-5-(4-nitrophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H12Cl2N4O2S
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1
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| 1 |
IC50 = 7780 nM
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CP0492788
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4-(Bis(2-chloroethyl)amino)-N-(2-bromophenyl)benzamide
Show/Hide
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C17H17BrCl2N2O
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1
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| 1 |
IC50 = 7820 nM
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CP0514506
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethylcinnamate
Show/Hide
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C15H15N3O4
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1
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| 1 |
IC50 = 7830 nM
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CP0930947
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(Z)-2-((E)-3-(2-chlorophenyl)-1-(4-methoxyphenyl)allylidene)hydrazinecarbothioamide
Show/Hide
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C17H16ClN3OS
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1
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| 1 |
IC50 = 7830 nM
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CP0526523
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methyl (2S)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylacetate
Show/Hide
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C27H21N3O3
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1
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| 1 |
IC50 = 7893 nM
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CP0918022
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2-(3-(4-Bromophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16BrN3O2S
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1
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| 1 |
IC50 = 7960 nM
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CP0235896
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(2E,6E)-2-[(2-bromophenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H21BrO3
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1
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| 1 |
IC50 = 8000 nM
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CP0400282
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3-(3,4-Dibromophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C17H15Br2N3OS
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1
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| 1 |
IC50 = 8090 nM
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CP0483737
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methyl 2-amino-4-(7-chlorotetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C25H20ClN7O3
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1
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| 1 |
IC50 = 8100 nM
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CP0452143
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-p-tolylacrylate
Show/Hide
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C16H17N3O4
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1
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| 1 |
IC50 = 8110 nM
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CP0935261
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2-(3-(4-Fluorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14FN3OS
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1
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| 1 |
IC50 = 8140 nM
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CP0373869
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5-(4-Chlorophenyl)-3-(3,4-dibromophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
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C16H12Br2ClN3S
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1
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| 1 |
IC50 = 8150 nM
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CP0847128
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2-(3,5-Bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
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C18H13Cl2N3OS
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1
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| 1 |
IC50 = 8160 nM
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CP0904564
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(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)isonicotinohydrazide
Show/Hide
|
C18H15BrN6O3
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1
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| 1 |
IC50 = 8190 nM
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CP0890834
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2-(3-(4-Fluorophenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16FN3OS
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1
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| 1 |
IC50 = 8360 nM
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CP0430869
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1-(4-Fluorobenzyl)-1-(2-hydroxy-5-methylbenzyl)-3-phenylthiourea
Show/Hide
|
C22H21FN2OS
|
1
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| 1 |
IC50 = 8540 nM
|
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CP0847121
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2-(3-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16ClN3O2S
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1
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| 1 |
IC50 = 8580 nM
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CP0003494
|
US9187397, 1 (curcumin)
Show/Hide
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C21H20O6
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1
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| 1 |
IC50 = 8600 nM
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CP0055701
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N-[3-[4-(1H-indazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]oxyphenyl]propanamide
Show/Hide
|
C25H28N8O2
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2
|
| 1 |
IC50 = 8600 nM
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| 2 |
IC50 > 10000 nM
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CP0853058
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(Z)-2-((E)-1-(4-methoxyphenyl)-3-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C17H17N3OS
|
1
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| 1 |
IC50 = 8660 nM
|
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CP0395482
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N-[(E)-[2-(4-chlorophenoxy)-6-methylquinolin-3-yl]methylideneamino]-2-(2-methyl-5-nitroimidazol-1-yl)acetamide
Show/Hide
|
C23H19ClN6O4
|
2
|
| 1 |
IC50 = 8660 nM
|
|
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| 2 |
IC50 = 19000 nM
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CP0500155
|
N-hexyl-2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetamide
Show/Hide
|
C23H25NO5
|
1
|
| 1 |
IC50 = 8710 nM
|
|
|
|
CP0540617
|
(E)-N-[4-(3-chloroanilino)quinazolin-6-yl]-3-thiophen-2-ylprop-2-enamide
Show/Hide
|
C21H15ClN4OS
|
1
|
| 1 |
IC50 = 8800 nM
|
|
|
|
CP0885545
|
2-(3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C20H19N3O3S
|
1
|
| 1 |
IC50 = 8890 nM
|
|
|
|
CP0449626
|
(Z)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)-2-(trifluoromethyl)prop-2-enamide
Show/Hide
|
C33H32ClF3N6O4
|
2
|
| 1 |
IC50 = 8900 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0479155
|
3-(3,4-Dibromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H12Br2FN3S
|
1
|
| 1 |
IC50 = 8920 nM
|
|
|
|
CP0066849
|
(E)-N-(4-methoxyphenyl)-3-phenylprop-2-enamide
Show/Hide
|
C16H15NO2
|
1
|
| 1 |
IC50 = 9050 nM
|
|
|
|
CP0518741
|
hexyl 2-(5-hydroxy-4-oxo-2-phenylchromen-7-yl)oxyacetate
Show/Hide
|
C23H24O6
|
1
|
| 1 |
IC50 = 9120 nM
|
|
|
|
CP0522057
|
1-(2-Hydroxy-3,5-dimethylbenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 9260 nM
|
|
|
|
CP0419650
|
(E)-N-(2-ethoxyphenyl)-3-phenylprop-2-enamide
Show/Hide
|
C17H17NO2
|
1
|
| 1 |
IC50 = 9350 nM
|
|
|
|
CP0507694
|
4-(Bis(2-chloroethyl)amino)-N-(2-chlorophenyl)benzamide
Show/Hide
|
C17H17Cl3N2O
|
1
|
| 1 |
IC50 = 9460 nM
|
|
|
|
CP0919939
|
(Z)-2-((E)-1-(3,4-dichlorophenyl)-3-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H13Cl2N3S
|
1
|
| 1 |
IC50 = 9780 nM
|
|
|
|
CP0536839
|
2,5-diphenyl-[1,3]thiazolo[3,2-b][1,2,4]triazole
Show/Hide
|
C16H11N3S
|
1
|
| 1 |
IC50 = 9800 nM
|
|
|
|
CP0400283
|
3-(3,4-Dibromophenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C17H15Br2N3S
|
1
|
| 1 |
IC50 = 9830 nM
|
|
|
|
CP0156026
|
(E)-N-(2-chlorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H12ClNO
|
1
|
| 1 |
IC50 = 9860 nM
|
|
|
|
CP0565989
|
5,6-diphenyl-N-[(1R)-1-phenylpropyl]furo[2,3-d]pyrimidin-4-amine
Show/Hide
|
C27H23N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0440322
|
(E)-N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enamide
Show/Hide
|
C34H35ClN8O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0385948
|
N-[4-[4-(1H-pyrazol-5-ylamino)quinazolin-2-yl]phenyl]propanamide
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409540
|
N-[3-[4-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]propanamide
Show/Hide
|
C17H18N6O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0410810
|
N-[4-[4-(1H-pyrazol-5-ylamino)quinazolin-2-yl]phenyl]prop-2-enamide
Show/Hide
|
C20H16N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0448936
|
N-[2-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]oxyphenyl]propanamide
Show/Hide
|
C22H28N8O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0456040
|
N-[2-[4-(1H-pyrazol-5-ylamino)quinazolin-2-yl]phenyl]propanamide
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0555778
|
N-[3-[4-(4-methylpiperazin-1-yl)-6-(1H-pyrazol-5-ylamino)pyrimidin-2-yl]oxyphenyl]propanamide
Show/Hide
|
C21H26N8O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0414116
|
4-tert-butyl-N-[2-methyl-3-[1-methyl-5-[4-(morpholine-4-carbonyl)-3-(prop-2-enoylamino)anilino]-6-oxopyridin-3-yl]phenyl]benzamide
Show/Hide
|
C38H41N5O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0139001
|
N-(4-fluorophenyl)-1-methyl-3-[[methyl-[2-(4-phenylphenyl)ethyl]amino]methyl]indole-5-carboxamide
Show/Hide
|
C32H30FN3O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0575807
|
(3S,4R)-3-fluoro-3-methyl-1-[4-[(5-propan-2-yl-8-pyrrolidin-1-yl-2,7-naphthyridin-3-yl)amino]pyrimidin-2-yl]piperidin-4-ol
Show/Hide
|
C25H32FN7O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0144578
|
(E)-N-(4-fluorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H12FNO
|
1
|
| 1 |
IC50 = 10020 nM
|
|
|
|
CP0935989
|
(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)benzohydrazide
Show/Hide
|
C19H16BrN5O3
|
1
|
| 1 |
IC50 = 10020 nM
|
|
|
|
CP0452146
|
5-(4-Bromophenyl)-3-(3,4-dibromophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H12Br3N3S
|
1
|
| 1 |
IC50 = 10060 nM
|
|
|
|
CP0411220
|
2-amino-4-[5-chloro-3-methyl-1-(4-methylphenyl)pyrazol-4-yl]-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C26H23ClN6O
|
1
|
| 1 |
IC50 = 10120 nM
|
|
|
|
CP0449638
|
(E)-N-(4-ethoxyphenyl)-3-phenylprop-2-enamide
Show/Hide
|
C17H17NO2
|
1
|
| 1 |
IC50 = 10230 nM
|
|
|
|
CP0414892
|
2-(2-methyl-5-nitroimidazol-1-yl)-N-[(E)-(2-phenoxyquinolin-3-yl)methylideneamino]acetamide
Show/Hide
|
C22H18N6O4
|
2
|
| 1 |
IC50 = 10350 nM
|
|
|
| 2 |
IC50 = 15300 nM
|
|
|
|
CP0460316
|
2-amino-4-(7-methyltetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C25H20N8O
|
1
|
| 1 |
IC50 = 10400 nM
|
|
|
|
CP0000042
|
10-hydroxy-18-methoxybetaenone
Show/Hide
|
C22H36O6
|
1
|
| 1 |
IC50 = 10500 nM
|
|
|
|
CP0475654
|
3-(3,4-Dibromophenyl)-5-(4-nitrophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H12Br2N4O2S
|
1
|
| 1 |
IC50 = 10640 nM
|
|
|
|
CP0853521
|
2-(3-(4-Fluorophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16FN3O2S
|
1
|
| 1 |
IC50 = 10690 nM
|
|
|
|
CP0913243
|
2-(2-(3-Chlorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8ClN3OS
|
1
|
| 1 |
IC50 = 10780 nM
|
|
|
|
CP0473224
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-methoxyphenyl)acrylate
Show/Hide
|
C16H17N3O5
|
1
|
| 1 |
IC50 = 10850 nM
|
|
|
|
CP0847126
|
2-(5-(4-Chlorophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13ClFN3OS
|
1
|
| 1 |
IC50 = 10920 nM
|
|
|
|
CP0917416
|
(Z)-2-((E)-3-(3-methoxyphenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C17H17N3OS
|
1
|
| 1 |
IC50 = 10950 nM
|
|
|
|
CP0433642
|
5-(2-Bromophenyl)-3-(3,4-dibromophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H12Br3N3S
|
1
|
| 1 |
IC50 = 10970 nM
|
|
|
|
CP0434511
|
ethyl 2-amino-4-(5-chloro-3-methyl-1-phenylpyrazol-4-yl)-7,7-dimethyl-5-oxo-1-pyridin-3-yl-6,8-dihydro-4H-quinoline-3-carboxylate
Show/Hide
|
C29H30ClN5O3
|
1
|
| 1 |
IC50 = 11180 nM
|
|
|
|
CP0452141
|
4-N-(3-bromophenyl)-6-N-[(2-methoxyphenyl)methyl]quinazoline-4,6-diamine
Show/Hide
|
C22H19BrN4O
|
1
|
| 1 |
IC50 = 11220 nM
|
|
|
|
CP0506137
|
3-(3,4-Dibromophenyl)-5-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H13Br2N3OS
|
1
|
| 1 |
IC50 = 11270 nM
|
|
|
|
CP0492787
|
4-(Bis(2-chloroethyl)amino)-N-(2-fluorophenyl)benzamide
Show/Hide
|
C17H17Cl2FN2O
|
1
|
| 1 |
IC50 = 11570 nM
|
|
|
|
CP0414125
|
(E)-N-(2,4-difluorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H11F2NO
|
1
|
| 1 |
IC50 = 11690 nM
|
|
|
|
CP0508914
|
5-bromo-N-(4-methylphenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C13H11BrN2O3S
|
1
|
| 1 |
IC50 = 12110 nM
|
|
|
|
CP0908986
|
(Z)-2-((E)-1-(4-bromophenyl)-3-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14BrN3S
|
1
|
| 1 |
IC50 = 12240 nM
|
|
|
|
CP0514555
|
5-(2-Chlorophenyl)-3-(3,4-dibromophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H12Br2ClN3S
|
1
|
| 1 |
IC50 = 12260 nM
|
|
|
|
CP0284836
|
(E)-N-(2-methylphenyl)-3-phenylprop-2-enamide
Show/Hide
|
C16H15NO
|
1
|
| 1 |
IC50 = 12290 nM
|
|
|
|
CP0431327
|
2-benzylsulfanyl-5-(2-methoxyphenyl)-1,3,4-oxadiazole
Show/Hide
|
C16H14N2O2S
|
1
|
| 1 |
IC50 = 12320 nM
|
|
|
|
CP0427702
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-fluorophenyl)acrylate
Show/Hide
|
C15H14FN3O4
|
1
|
| 1 |
IC50 = 12420 nM
|
|
|
|
CP0903773
|
(E)-N'-(1-(4-bromophenyl)-2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylidene)-4-chlorobenzohydrazide
Show/Hide
|
C19H15BrClN5O3
|
1
|
| 1 |
IC50 = 12450 nM
|
|
|
|
CP0066866
|
(E)-N-(4-methylphenyl)-3-phenylprop-2-enamide
Show/Hide
|
C16H15NO
|
1
|
| 1 |
IC50 = 12690 nM
|
|
|
|
CP0515561
|
(E)-3-phenyl-N-(3,4,5-trifluorophenyl)prop-2-enamide
Show/Hide
|
C15H10F3NO
|
1
|
| 1 |
IC50 = 12880 nM
|
|
|
|
CP0553312
|
(E)-N-(3,5-difluorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H11F2NO
|
1
|
| 1 |
IC50 = 13230 nM
|
|
|
|
CP0436839
|
3-(3,4-Dibromophenyl)-5-(2-fluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Show/Hide
|
C16H12Br2FN3S
|
1
|
| 1 |
IC50 = 13370 nM
|
|
|
|
CP0859408
|
2-(2-(3-Fluorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8FN3OS
|
1
|
| 1 |
IC50 = 13530 nM
|
|
|
|
CP0065458
|
(E)-N-(4-chlorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H12ClNO
|
1
|
| 1 |
IC50 = 13710 nM
|
|
|
|
CP0400315
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-methoxyphenyl)acrylate
Show/Hide
|
C16H17N3O5
|
1
|
| 1 |
IC50 = 13870 nM
|
|
|
|
CP0495419
|
4-N-(3-chlorophenyl)-6-N-[(2-methoxyphenyl)methyl]quinazoline-4,6-diamine
Show/Hide
|
C22H19ClN4O
|
1
|
| 1 |
IC50 = 13880 nM
|
|
|
|
CP0481706
|
(E)-N-(3,5-dichlorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H11Cl2NO
|
1
|
| 1 |
IC50 = 13930 nM
|
|
|
|
CP0847127
|
2-(3-(4-Chlorophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13ClFN3OS
|
1
|
| 1 |
IC50 = 14210 nM
|
|
|
|
CP0428883
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-nitrophenyl)acrylate
Show/Hide
|
C15H14N4O6
|
1
|
| 1 |
IC50 = 14530 nM
|
|
|
|
CP0391441
|
(E)-3-phenyl-N-(4-propan-2-ylphenyl)prop-2-enamide
Show/Hide
|
C18H19NO
|
1
|
| 1 |
IC50 = 14580 nM
|
|
|
|
CP0067353
|
(E)-N-(3-chlorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H12ClNO
|
1
|
| 1 |
IC50 = 14590 nM
|
|
|
|
CP0557765
|
2-amino-4-[5-chloro-3-methyl-1-(4-methylphenyl)pyrazol-4-yl]-7,7-dimethyl-5-oxo-1-pyridin-3-yl-6,8-dihydro-4H-quinoline-3-carbonitrile
Show/Hide
|
C28H27ClN6O
|
1
|
| 1 |
IC50 = 14700 nM
|
|
|
|
CP0426999
|
4-(Bis(2-chloroethyl)amino)-N-methyl-N-phenylbenzamide
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 = 14720 nM
|
|
|
|
CP0917267
|
(Z)-2-((E)-3-(4-methoxyphenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C17H17N3OS
|
1
|
| 1 |
IC50 = 14830 nM
|
|
|
|
CP0499489
|
2-chloro-6-methyl-N-(4-methylphenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C14H13ClN2O3S
|
1
|
| 1 |
IC50 = 15020 nM
|
|
|
|
CP0493538
|
1-(3-(3,4-dimethylphenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C20H22N2O2
|
1
|
| 1 |
IC50 = 15240 nM
|
|
|
|
CP0450492
|
(2E,6E)-2-[(4-chlorophenyl)methylidene]-6-[(3,5-dimethoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C22H21ClO3
|
1
|
| 1 |
IC50 = 15300 nM
|
|
|
|
CP0471054
|
1-(3-(3,4-Dimethylphenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C19H19FN2O
|
1
|
| 1 |
IC50 = 15560 nM
|
|
|
|
CP0513096
|
N-(4-bromophenyl)sulfonyl-2-chloropyridine-3-carboxamide
Show/Hide
|
C12H8BrClN2O3S
|
1
|
| 1 |
IC50 = 15680 nM
|
|
|
|
CP0529421
|
(E)-N-(2-bromophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H12BrNO
|
1
|
| 1 |
IC50 = 15740 nM
|
|
|
|
CP0514556
|
1-(5-(4-chlorophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C17H13Cl3N2O
|
1
|
| 1 |
IC50 = 16140 nM
|
|
|
|
CP0485367
|
(E)-N-(2,4-dichlorophenyl)-3-phenylprop-2-enamide
Show/Hide
|
C15H11Cl2NO
|
1
|
| 1 |
IC50 = 16170 nM
|
|
|
|
CP0930351
|
N-(1-(1-Acryloylpiperidin-4-yl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H23F3N4O2
|
2
|
| 1 |
IC50 = 16460 nM
|
|
|
| 2 |
IC50 > 37670 nM
|
|
|
|
CP0087791
|
2-benzylsulfanyl-5-phenyl-1,3,4-oxadiazole
Show/Hide
|
C15H12N2OS
|
1
|
| 1 |
IC50 = 16630 nM
|
|
|
|
CP0494510
|
ethyl 2-amino-4-(7-chlorotetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C26H22ClN7O3
|
1
|
| 1 |
IC50 = 16700 nM
|
|
|
|
CP0878668
|
2-(3,5-Bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13F2N3OS
|
1
|
| 1 |
IC50 = 16920 nM
|
|
|
|
CP0400221
|
1-(3-(3,4-Dichlorophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C18H16Cl2N2O2
|
1
|
| 1 |
IC50 = 17190 nM
|
|
|
|
CP0433643
|
1-(5-(3,5-Dimethoxyphenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
IC50 = 17310 nM
|
|
|
|
CP0935720
|
(Z)-2-((E)-1-phenyl-3-p-tolylallylidene)hydrazinecarbothioamide
Show/Hide
|
C17H17N3S
|
1
|
| 1 |
IC50 = 17390 nM
|
|
|
|
CP0471055
|
1-(3-(3,4-Dimethylphenyl)-5-p-tolyl-4,5-dihydro-1Hpyrazol-1-yl)ethanone
Show/Hide
|
C20H22N2O
|
1
|
| 1 |
IC50 = 17490 nM
|
|
|
|
CP0492790
|
N-benzyl-4-[bis(2-chloroethyl)amino]benzamide
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 = 17510 nM
|
|
|
|
CP0553887
|
2-amino-4-(5-chloro-3-methyl-1-phenylpyrazol-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C25H21ClN6O
|
1
|
| 1 |
IC50 = 18020 nM
|
|
|
|
CP0407065
|
1-Butyl-1-(5-chloro-2-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C18H21ClN2OS
|
1
|
| 1 |
IC50 = 18120 nM
|
|
|
|
CP0499488
|
6-chloro-N-(4-chlorophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H8Cl2N2O3S
|
1
|
| 1 |
IC50 = 18150 nM
|
|
|
|
CP0509091
|
2-amino-4-(7-chlorotetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C24H17ClN8O
|
1
|
| 1 |
IC50 = 18300 nM
|
|
|
|
CP0522072
|
1-(3-(3,4-Dichlorophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C17H13Cl2FN2O
|
1
|
| 1 |
IC50 = 18350 nM
|
|
|
|
CP0426046
|
1-(5-(4-bromophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C17H13BrCl2N2O
|
1
|
| 1 |
IC50 = 18450 nM
|
|
|
|
CP0415057
|
(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(4-methoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C23H24O4
|
1
|
| 1 |
IC50 = 18600 nM
|
|
|
|
CP0918588
|
(Z)-2-((E)-3-(4-fluorophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14FN3S
|
1
|
| 1 |
IC50 = 19120 nM
|
|
|
|
CP0426998
|
4-(Bis(2-chloroethyl)amino)-N-(4-nitrophenyl)benzamide
Show/Hide
|
C17H17Cl2N3O3
|
1
|
| 1 |
IC50 = 19260 nM
|
|
|
|
CP0885036
|
2-(2-(3-Hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H9N3O2S
|
1
|
| 1 |
IC50 = 19320 nM
|
|
|
|
CP0493535
|
1-(3-(3,4-Dichlorophenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C18H16Cl2N2O
|
1
|
| 1 |
IC50 = 19320 nM
|
|
|
|
CP0489637
|
1-(4-Fluorobenzyl)-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylthiourea
Show/Hide
|
C23H23FN2OS
|
1
|
| 1 |
IC50 = 19410 nM
|
|
|
|
CP0184871
|
(E)-N-(3-methylphenyl)-3-phenylprop-2-enamide
Show/Hide
|
C16H15NO
|
1
|
| 1 |
IC50 = 19690 nM
|
|
|
|
CP0400287
|
1-(5-(4-Chlorophenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C19H19ClN2O
|
1
|
| 1 |
IC50 = 19730 nM
|
|
|
|
CP0503867
|
2-chloro-N-(4-chlorophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H8Cl2N2O3S
|
1
|
| 1 |
IC50 = 19830 nM
|
|
|
|
CP0039971
|
NSC-114945
Show/Hide
|
C30H48O3
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0272224
|
4-Epi-Hederagenin
Show/Hide
|
C30H48O4
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0402981
|
4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-10-(4-nitrobenzoyl)oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C41H58N2O9
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0426071
|
4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(E)-3-(1,3-benzodioxol-5-yl)prop-2-enoyl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C44H61NO9
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0426073
|
4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-10-phenylmethoxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C41H61NO6
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0530037
|
4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-2,2,6a,6b,9,9,12a-heptamethyl-10-prop-2-enoyloxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C37H57NO7
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0548765
|
4-nitrooxybutyl (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-benzoyloxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Show/Hide
|
C41H59NO7
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0388287
|
1-(3-(3,4-Dimethylphenyl)-5-phenyl-4,5-dihydro-1Hpyrazol-1-yl)ethanone
Show/Hide
|
C19H20N2O
|
1
|
| 1 |
IC50 = 20040 nM
|
|
|
|
CP0509661
|
N-(benzenesulfonyl)-5-bromopyridine-3-carboxamide
Show/Hide
|
C12H9BrN2O3S
|
1
|
| 1 |
IC50 = 20190 nM
|
|
|
|
CP0917417
|
(Z)-2-((E)-3-(4-chlorophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14ClN3S
|
1
|
| 1 |
IC50 = 20480 nM
|
|
|
|
CP0438768
|
1-(5-(4-bromophenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C19H19BrN2O
|
1
|
| 1 |
IC50 = 20610 nM
|
|
|
|
CP0510953
|
(2E,6E)-2-[(3,5-dimethoxyphenyl)methylidene]-6-[(2-methoxyphenyl)methylidene]cyclohexan-1-one
Show/Hide
|
C23H24O4
|
1
|
| 1 |
IC50 = 20800 nM
|
|
|
|
CP0372727
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2-chlorophenyl)acrylate
Show/Hide
|
C15H14ClN3O4
|
1
|
| 1 |
IC50 = 20810 nM
|
|
|
|
CP0400228
|
1-(5-(2-Chlorophenyl)-3-(3,4-dimethylphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C19H19ClN2O
|
1
|
| 1 |
IC50 = 21480 nM
|
|
|
|
CP0509663
|
N-(benzenesulfonyl)-2-chloro-6-methylpyridine-3-carboxamide
Show/Hide
|
C13H11ClN2O3S
|
1
|
| 1 |
IC50 = 21560 nM
|
|
|
|
CP0447437
|
1-(4-Fluorobenzyl)-1-(2-hydroxy-5-methylbenzyl)-3-phenylurea
Show/Hide
|
C22H21FN2O2
|
1
|
| 1 |
IC50 = 21710 nM
|
|
|
|
CP0491208
|
1-(5-Bromo-2-hydroxybenzyl)-1-butyl-3-phenylthiourea
Show/Hide
|
C18H21BrN2OS
|
1
|
| 1 |
IC50 = 22040 nM
|
|
|
|
CP0941577
|
(Z)-2-((E)-3-(2-fluorophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14FN3S
|
1
|
| 1 |
IC50 = 22360 nM
|
|
|
|
CP0498687
|
4-(Bis(2-chloroethyl)amino)-N-butylbenzamide
Show/Hide
|
C15H22Cl2N2O
|
1
|
| 1 |
IC50 = 22810 nM
|
|
|
|
CP0046712
|
(E)-N,3-diphenylprop-2-enamide
Show/Hide
|
C15H13NO
|
1
|
| 1 |
IC50 = 23160 nM
|
|
|
|
CP0943429
|
(Z)-2-((E)-3-(2-chlorophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14ClN3S
|
1
|
| 1 |
IC50 = 23270 nM
|
|
|
|
CP0905450
|
2-(2-(3-Methylbenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C11H11N3OS
|
1
|
| 1 |
IC50 = 23490 nM
|
|
|
|
CP0553905
|
2-amino-4-[5-chloro-1-(4-chlorophenyl)-3-methylpyrazol-4-yl]-7,7-dimethyl-5-oxo-1-pyridin-3-yl-6,8-dihydro-4H-quinoline-3-carbonitrile
Show/Hide
|
C27H24Cl2N6O
|
1
|
| 1 |
IC50 = 24050 nM
|
|
|
|
CP0473162
|
1-(5-(2-Chlorophenyl)-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C17H13Cl3N2O
|
1
|
| 1 |
IC50 = 24150 nM
|
|
|
|
CP0228398
|
(6E)-6-[4-(3-pyridinylmethylamino)-1H-quinazolin-2-ylidene]-1-cyclohexa-2,4-dienone
Show/Hide
|
C20H16N4O
|
1
|
| 1 |
IC50 = 24300 nM
|
|
|
|
CP0514950
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2-bromophenyl)acrylate
Show/Hide
|
C15H14BrN3O4
|
1
|
| 1 |
IC50 = 24320 nM
|
|
|
|
CP0429967
|
1-Butyl-1-(3,5-dichloro-2-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C18H20Cl2N2OS
|
1
|
| 1 |
IC50 = 24650 nM
|
|
|
|
CP0083178
|
N-(4-methylphenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C13H12N2O3S
|
1
|
| 1 |
IC50 = 24830 nM
|
|
|
|
CP0483695
|
ethyl 5-benzyl-4-[(1-benzylindazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C30H26N6O2
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0401884
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(2-nitrophenyl)acrylate
Show/Hide
|
C15H14N4O6
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0462400
|
N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]-5-methylhexanamide
Show/Hide
|
C33H34N4O3
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0273765
|
N-(4-chlorophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H9ClN2O3S
|
1
|
| 1 |
IC50 = 25360 nM
|
|
|
|
CP0438766
|
1-(3-(3,4-Dichlorophenyl)-5-(3,5-dimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
Show/Hide
|
C19H18Cl2N2O3
|
1
|
| 1 |
IC50 = 25470 nM
|
|
|
|
CP0893971
|
(Z)-2-((E)-3-(2-bromophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14BrN3S
|
1
|
| 1 |
IC50 = 26000 nM
|
|
|
|
CP0523769
|
2-benzylsulfanyl-5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazole
Show/Hide
|
C17H16N2O3S
|
1
|
| 1 |
IC50 = 26060 nM
|
|
|
|
CP0939805
|
(Z)-2-((E)-3-(4-bromophenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C16H14BrN3S
|
1
|
| 1 |
IC50 = 26560 nM
|
|
|
|
CP0517623
|
(E)-2((E)-(3-nitrobenzylidene)hydrazono)thiazolidin-4-one (8)
Show/Hide
|
C10H8N4O3S
|
1
|
| 1 |
IC50 = 26610 nM
|
|
|
|
CP0400314
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2-fluorophenyl)acrylate
Show/Hide
|
C15H14FN3O4
|
1
|
| 1 |
IC50 = 26740 nM
|
|
|
|
CP0913244
|
2-(2-Cyclooctylidenehydrazono)thiazolidin-4-one
Show/Hide
|
C11H17N3OS
|
1
|
| 1 |
IC50 = 27000 nM
|
|
|
|
CP0527182
|
2-chloro-N-(4-methylphenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C13H11ClN2O3S
|
1
|
| 1 |
IC50 = 27050 nM
|
|
|
|
CP0440139
|
1-(4-fluorobenzyl)-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylurea
Show/Hide
|
C23H23FN2O2
|
1
|
| 1 |
IC50 = 27350 nM
|
|
|
|
CP0004798
|
(R)-1,3,6,8-tetrahydroxy-2-(1-methoxyethyl)anthracene-9,10-dione
Show/Hide
|
C17H14O7
|
1
|
| 1 |
IC50 = 27500 nM
|
|
|
|
CP0499486
|
2-chloro-N-(4-fluorophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H8ClFN2O3S
|
1
|
| 1 |
IC50 = 28660 nM
|
|
|
|
CP0493536
|
1-(3-(3,4-Dichlorophenyl)-5-phenyl-4,5-dihydro-1Hpyrazol-1-yl)ethanone
Show/Hide
|
C17H14Cl2N2O
|
1
|
| 1 |
IC50 = 28690 nM
|
|
|
|
CP0495163
|
N-(4-bromophenyl)sulfonyl-6-chloropyridine-3-carboxamide
Show/Hide
|
C12H8BrClN2O3S
|
1
|
| 1 |
IC50 = 29070 nM
|
|
|
|
CP0421854
|
4-(Bis(2-chloroethyl)amino)-N,N-dipropylbenzamide
Show/Hide
|
C17H26Cl2N2O
|
1
|
| 1 |
IC50 = 29830 nM
|
|
|
|
CP0414989
|
N-TERT-BUTYLCINNAMAMIDE
Show/Hide
|
C13H17NO
|
1
|
| 1 |
IC50 = 29850 nM
|
|
|
|
CP0093615
|
N-(benzenesulfonyl)pyridine-3-carboxamide
Show/Hide
|
C12H10N2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0273768
|
N-(4-bromophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H9BrN2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0338191
|
N-(4-fluorophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H9FN2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0499487
|
6-chloro-N-(4-fluorophenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C12H8ClFN2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0508915
|
N-(benzenesulfonyl)-2-chloropyridine-3-carboxamide
Show/Hide
|
C12H9ClN2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0509662
|
6-chloro-N-(4-methylphenyl)sulfonylpyridine-3-carboxamide
Show/Hide
|
C13H11ClN2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0513097
|
N-(benzenesulfonyl)-6-chloropyridine-3-carboxamide
Show/Hide
|
C12H9ClN2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0498689
|
4-(Bis(2-chloroethyl)amino)-N,N-dibutylbenzamide
Show/Hide
|
C19H30Cl2N2O
|
1
|
| 1 |
IC50 = 31180 nM
|
|
|
|
CP0859409
|
2-(2-(3-Methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C11H11N3O2S
|
1
|
| 1 |
IC50 = 31250 nM
|
|
|
|
CP0427001
|
4-(Bis(2-chloroethyl)amino)-N-tert-butylbenzamide
Show/Hide
|
C15H22Cl2N2O
|
1
|
| 1 |
IC50 = 31430 nM
|
|
|
|
CP0491209
|
1-Butyl-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C18H20Br2N2OS
|
1
|
| 1 |
IC50 = 31940 nM
|
|
|
|
CP0427704
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(2-methoxyphenyl)acrylate
Show/Hide
|
C16H17N3O5
|
1
|
| 1 |
IC50 = 32000 nM
|
|
|
|
CP0489669
|
1-Butyl-1-(5-chloro-2-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C18H21ClN2O2
|
1
|
| 1 |
IC50 = 32120 nM
|
|
|
|
CP0555187
|
2-amino-4-(5-chloro-3-methyl-1-phenylpyrazol-4-yl)-7,7-dimethyl-5-oxo-1-pyridin-3-yl-6,8-dihydro-4H-quinoline-3-carbonitrile
Show/Hide
|
C27H25ClN6O
|
1
|
| 1 |
IC50 = 32130 nM
|
|
|
|
CP0868714
|
N-(1-(2-Acrylamidophenyl)-5-methyl-1H-benzo[d]imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H19F3N4O2
|
2
|
| 1 |
IC50 > 32770 nM
|
|
|
| 2 |
IC50 > 50000 nM
|
|
|
|
CP0923190
|
(Z)-2-((E)-3-(2-methoxyphenyl)-1-phenylallylidene)hydrazinecarbothioamide
Show/Hide
|
C17H17N3OS
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0523766
|
2-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-5-methylphenol
Show/Hide
|
C16H14N2O2S
|
1
|
| 1 |
IC50 = 34250 nM
|
|
|
|
CP0009041
|
5-propan-2-yl-7,8-dihydro-6H-indeno[1,2-b]indole-9,10-dione
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 > 35000 nM
|
|
|
|
CP0383876
|
4-(Bis(2-chloroethyl)amino)-N-cyclopentylbenzamide
Show/Hide
|
C16H22Cl2N2O
|
1
|
| 1 |
IC50 = 35290 nM
|
|
|
|
CP0913245
|
2-(2-Cycloheptylidenehydrazono)thiazolidin-4-one
Show/Hide
|
C10H15N3OS
|
1
|
| 1 |
IC50 = 36000 nM
|
|
|
|
CP0406246
|
1-(5-Bromo-2-hydroxybenzyl)-1-butyl-3-phenylurea
Show/Hide
|
C18H21BrN2O2
|
1
|
| 1 |
IC50 = 36880 nM
|
|
|
|
CP0003765
|
(R)-1,3,6,8-tetrahydroxy-2-(1-hydroxyethyl)anthracene-9,10-dione
Show/Hide
|
C16H12O7
|
1
|
| 1 |
IC50 = 37500 nM
|
|
|
|
CP0395790
|
2-benzylsulfanyl-5-(2-nitrophenyl)-1,3,4-oxadiazole
Show/Hide
|
C15H11N3O3S
|
1
|
| 1 |
IC50 = 38320 nM
|
|
|
|
CP0467518
|
2-benzylsulfanyl-5-(2-ethoxyphenyl)-1,3,4-oxadiazole
Show/Hide
|
C17H16N2O2S
|
1
|
| 1 |
IC50 = 38430 nM
|
|
|
|
CP0530021
|
N-DODECYLCINNAMAMIDE
Show/Hide
|
C21H33NO
|
1
|
| 1 |
IC50 = 38460 nM
|
|
|
|
CP0000043
|
(R)-1,2,3,6,8-pentahydroxy-7-(1-methoxyethyl)anthracene-9,10-dione
Show/Hide
|
C17H14O8
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
|
CP0924340
|
2-(2-Cyclohexylidenehydrazono)thiazolidin-4-one
Show/Hide
|
C9H13N3OS
|
1
|
| 1 |
IC50 = 41000 nM
|
|
|
|
CP0440209
|
1-Butyl-1-(2-hydroxy-5-methylbenzyl)-3-phenylthiourea
Show/Hide
|
C19H24N2OS
|
1
|
| 1 |
IC50 = 43210 nM
|
|
|
|
CP0885037
|
2-(2-Cyclobutylidenehydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C7H9N3OS
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0926266
|
2-(2-Cyclopentylidenehydrazono)thiazolidin-4-one
Show/Hide
|
C8H11N3OS
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0401403
|
1-Butyl-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C18H20Br2N2O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0429956
|
1-Butyl-1-(2-hydroxy-5-methylbenzyl)-3-phenylurea
Show/Hide
|
C19H24N2O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0430867
|
1-Butyl-1-(3,5-dichloro-2-hydroxybenzyl)-3-phenylturea
Show/Hide
|
C18H20Cl2N2O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0439054
|
1-Butyl-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylthiourea
Show/Hide
|
C23H24N2OS
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0491205
|
1-Butyl-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylurea
Show/Hide
|
C20H26N2O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0492789
|
4-(Bis(2-chloroethyl)amino)-N-(3-morpholinopropyl)benzamide
Show/Hide
|
C18H27Cl2N3O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0517599
|
4-(Bis(2-chloroethyl)amino)-N-dodecylbenzamide
Show/Hide
|
C23H38Cl2N2O
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0857254
|
N-(1-(1-Acryloylazepan-4-yl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0857255
|
N-(1-(cis-4-Acrylamidocyclohexyl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0919331
|
N-(1-(1-Acryloylpyrrolidin-3-yl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H21F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0930350
|
N-(1-(2-Acrylamidoethyl)-5-methyl-1H-benzo[d]imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H19F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0850462
|
N-(1-(4-Acrylamidophenyl)-5-methyl-1H-benzo[d]imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H19F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0906062
|
rac-N-(1-(trans-2-Acrylamidocyclohexyl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0929231
|
N-(1-(1-Acryloylazetidin-3-yl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H19F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0930352
|
N-(1-(trans-4-Acrylamidocyclohexyl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0958451
|
rac-N-(1-(cis-2-Acrylamidocyclohexyl)-5-methyl-1H-benzo[d]-imidazol-2-yl)-3-(trifluoromethyl)benzamide
Show/Hide
|
C25H25F3N4O2
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0327137
|
4-hydroxy-3-[4-(pyridin-3-ylmethylamino)quinazolin-2-yl]benzonitrile
Show/Hide
|
C21H15N5O
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0484722
|
methyl 4-hydroxy-3-[4-(pyridin-3-ylmethylamino)quinazolin-2-yl]benzoate
Show/Hide
|
C22H18N4O3
|
1
|
| 1 |
IC50 > 50000 nM
|
|
|
|
CP0010496
|
10-hydroxy-18-N-2-naphthyl-N-phenylaminobetaenone
Show/Hide
|
C37H45NO5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0438691
|
methyl 1-[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]pyrrolidine-2-carboxylate
Show/Hide
|
C27H27ClN6O5
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0464545
|
2-[[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]amino]acetic acid
Show/Hide
|
C23H21ClN6O5
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0554434
|
methyl 2-[[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]amino]propanoate
Show/Hide
|
C25H25ClN6O5
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0559128
|
methyl 2-[[2-[4-[[5-chloro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]acetyl]amino]acetate
Show/Hide
|
C24H23ClN6O5
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0404835
|
N-[3-[[5-chloro-2-[3-chloro-4-(2-morpholin-4-ylethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Show/Hide
|
C25H26Cl2N6O3
|
2
|
| 1 |
IC50 > 100 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0403369
|
1-benzyl-3-[4-(4-phenoxyanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C28H23N5OS
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0407942
|
1-benzyl-3-[4-[4-(pyridin-2-ylsulfamoyl)anilino]quinazolin-6-yl]thiourea
Show/Hide
|
C27H23N7O2S2
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0458419
|
1-benzyl-3-[4-(2,3-dimethylanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C24H23N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0458420
|
1-benzyl-3-[4-(4-tert-butylanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C26H27N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0472393
|
1-benzyl-3-[4-(4-bromoanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C22H18BrN5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0474304
|
1-benzyl-3-[4-(4-sulfamoylanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C22H20N6O2S2
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0474306
|
1-benzyl-3-[4-[4-(diaminomethylideneamino)sulfonylanilino]quinazolin-6-yl]thiourea
Show/Hide
|
C23H22N8O2S2
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0474308
|
1-[3,5-bis(trifluoromethyl)phenyl]-3-[4-(3-bromoanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C23H14BrF6N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0507076
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-[4-(trifluoromethyl)phenyl]thiourea
Show/Hide
|
C22H15BrF3N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0513578
|
1-benzyl-3-[4-(2-bromoanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C22H18BrN5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0513579
|
1-benzyl-3-[4-(pyridin-3-ylamino)quinazolin-6-yl]thiourea
Show/Hide
|
C21H18N6S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0547399
|
1-benzyl-3-[4-(4-propan-2-ylanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C25H25N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0547400
|
1-benzyl-3-[4-(4-phenylanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C28H23N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0558591
|
1-[4-(3-bromoanilino)quinazolin-6-yl]-3-[4-chloro-3-(trifluoromethyl)phenyl]thiourea
Show/Hide
|
C22H14BrClF3N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0558602
|
1-benzyl-3-[4-(4-hydroxyanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C22H19N5OS
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0561540
|
1-benzyl-3-[4-(3-ethylanilino)quinazolin-6-yl]thiourea
Show/Hide
|
C24H23N5S
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0443805
|
[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(2,4-dimethylphenyl)-4-oxobut-2-enoate
Show/Hide
|
C28H26O7
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0475569
|
[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(2,5-dimethylphenyl)-4-oxobut-2-enoate
Show/Hide
|
C28H26O7
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0550963
|
[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-(3-bromo-4-methylphenyl)-4-oxobut-2-enoate
Show/Hide
|
C27H23BrO7
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0560076
|
[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (Z)-4-oxo-4-phenylbut-2-enoate
Show/Hide
|
C26H22O7
|
1
|
| 1 |
IC50 > 150 nM
|
|
|
|
CP0158854
|
6-(2-chlorophenyl)-5-methyl-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-8-[(3S)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C34H40ClN7O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0359309
|
6-(4-chlorophenyl)-5-methyl-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C34H40ClN7O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0363703
|
6-(3-chlorophenyl)-5-methyl-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-8-[(3R)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C34H40ClN7O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0561757
|
5-methyl-2-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-6-phenyl-8-[(3R)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C34H41N7O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0910828
|
N-(3-chlorobenzyl)-6-nitro-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C18H13ClN4O2
|
1
|
| 1 |
Ki = 80 nM
|
|
|
|
CP0853484
|
N4-(3-bromobenzyl)-9H-pyrido[2,3-b]indole-4,6-diamine
Show/Hide
|
C18H15BrN4
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0952563
|
N-(3-bromobenzyl)-6-nitro-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C18H13BrN4O2
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0902054
|
N4-(3-chlorobenzyl)-9H-pyrido[2,3-b]indole-4,6-diamine
Show/Hide
|
C18H15ClN4
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0966032
|
N4-(3-methoxybenzyl)benzofuro[2,3-b]pyridine-4,6-diamine
Show/Hide
|
C19H17N3O2
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0957790
|
N4-(3-bromobenzyl)benzofuro[2,3-b]pyridine-4,6-diamine
Show/Hide
|
C18H14BrN3O
|
1
|
| 1 |
Ki = 230 nM
|
|
|
|
CP0902055
|
N4-(3-methoxybenzyl)-9H-pyrido[2,3-b]indole-4,6-diamine
Show/Hide
|
C19H18N4O
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0968343
|
N-(3-methoxybenzyl)-6-nitro-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C19H16N4O3
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0902051
|
N4-(3-chlorobenzyl)benzofuro[2,3-b]pyridine-4,6-diamine
Show/Hide
|
C18H14ClN3O
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0883772
|
N-(3-bromobenzyl)-6-nitrobenzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C18H12BrN3O3
|
1
|
| 1 |
Ki = 680 nM
|
|
|
|
CP0883773
|
N-(4-bromobenzyl)-6-nitrobenzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C18H12BrN3O3
|
1
|
| 1 |
Ki = 810 nM
|
|
|
|
CP0950866
|
6-nitro-N-(3-nitrobenzyl)benzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C18H12N4O5
|
1
|
| 1 |
Ki = 930 nM
|
|
|
|
CP0853486
|
N4-(3-aminobenzyl)benzofuro[2,3-b]pyridine-4,6-diamine
Show/Hide
|
C18H16N4O
|
1
|
| 1 |
Ki = 940 nM
|
|
|
|
CP0957789
|
N-(3-chlorobenzyl)-6-nitrobenzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C18H12ClN3O3
|
1
|
| 1 |
Ki = 1360 nM
|
|
|
|
CP0026959
|
N-[(4-methoxyphenyl)methyl]-[1]benzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C19H16N2O2
|
1
|
| 1 |
Ki = 1430 nM
|
|
|
|
CP0941811
|
N-(4-methoxybenzyl)-6-nitrobenzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C19H15N3O4
|
1
|
| 1 |
Ki = 2050 nM
|
|
|
|
CP0853485
|
N-(4-chlorobenzyl)-6-nitrobenzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C18H12ClN3O3
|
1
|
| 1 |
Ki = 2520 nM
|
|
|
|
CP0853483
|
N-(3-methoxybenzyl)-6-nitrobenzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C19H15N3O4
|
1
|
| 1 |
Ki = 2740 nM
|
|
|
|
CP0952562
|
N-(3-aminobenzyl)-6-nitrobenzofuro[2,3-b]pyridin-4-amine
Show/Hide
|
C18H14N4O3
|
1
|
| 1 |
Ki = 3590 nM
|
|
|
