Brief Information of the Compound and Protein
Compound Name
N-[3-[4-(1H-pyrazol-5-ylamino)quinazolin-2-yl]phenyl]propanamide
    Show/Hide
PubChem ID
CID: 122186135
Canonical SMILES
CCC(=O)Nc1cccc(c1)-c1nc(Nc2cc[nH]n2)c2ccccc2n1
    Show/Hide
Compound Formula C20H18N6O
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
2
IC50 = 1900 nM
   TI
   LI
   LO
   TS
3
IC50 = 3700 nM
   TI
   LI
   LO
   TS