Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-2-fluoro-5-hydroxybenzamide
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 PubChem ID
CID: 155818892
Canonical SMILES
CSc1nc(c([nH]1)-c1ccnc(NC(C)=O)c1)-c1cccc(NC(=O)c2cc(O)ccc2F)c1
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Compound Formula C24H20FN5O3S
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 5.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 6.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 8 nM
   TI
   LI
   LO
   TS