General Information of the Compound
| Compound ID |
CP0139001
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| Compound Name |
N-(4-fluorophenyl)-1-methyl-3-[[methyl-[2-(4-phenylphenyl)ethyl]amino]methyl]indole-5-carboxamide
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| Structure |
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| Formula |
C32H30FN3O
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| Molecular Weight |
491.61
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| Canonical SMILES |
CN(CCc1ccc(cc1)-c1ccccc1)Cc1cn(C)c2ccc(cc12)C(=O)Nc1ccc(F)cc1
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| InChI |
InChI=1S/C32H30FN3O/c1-35(19-18-23-8-10-25(11-9-23)24-6-4-3-5-7-24)21-27-22-36(2)31-17-12-26(20-30(27)31)32(37)34-29-15-13-28(33)14-16-29/h3-17,20,22H,18-19,21H2,1-2H3,(H,34,37)
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| InChIKey |
XYNOVGMRAYSMEO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01093, 3-phosphoinositide-dependent protein kinase 1
Protein ID: PT01390, BDNF/NT-3 growth factors receptor
Protein ID: PT01210, Casein kinase II subunit alpha
Protein ID: PT01246, Casein kinase II subunit alpha'
Protein ID: PT01080, Dual specificity mitogen-activated protein kinase kinase 1
Protein ID: PT01030, Dual specificity protein kinase CLK1
Protein ID: PT00922, Epidermal growth factor receptor
Protein ID: PT01091, Fibroblast growth factor receptor 1
Protein ID: PT01115, Fibroblast growth factor receptor 2
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT01141, Focal adhesion kinase 1
Protein ID: PT01201, Hepatocyte growth factor receptor
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT01572, Mitogen-activated protein kinase 15
Protein ID: PT02105, Mitogen-activated protein kinase 7
Protein ID: PT02262, Mitogen-activated protein kinase kinase kinase 1
Protein ID: PT01092, Platelet-derived growth factor receptor alpha
Protein ID: PT00844, Platelet-derived growth factor receptor beta
Protein ID: PT00879, Proto-oncogene tyrosine-protein kinase Src
Protein ID: PT01131, RAC-beta serine/threonine-protein kinase
Protein ID: PT01233, Receptor tyrosine-protein kinase erbB-2
Protein ID: PT01159, Receptor tyrosine-protein kinase erbB-4
Protein ID: PT01165, SRSF protein kinase 1
Protein ID: PT01071, Tyrosine-protein kinase ABL1
Protein ID: PT01142, Vascular endothelial growth factor receptor 1
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Protein ID: PT00925, Vascular endothelial growth factor receptor 3
Protein ID: PT01675, Wee1-like protein kinase
Cell Viability or Cytotoxicity Assay