Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]prop-2-en-1-one
    Show/Hide
 PubChem ID
CID: 168290060
Canonical SMILES
CN1CCN(CC1)c1ccc(Nc2nc(OC3CCN(CC3)C(=O)C=C)c3sccc3n2)cc1F
    Show/Hide
Compound Formula C25H29FN6O2S
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 10.32 nM
   TI
   LI
   LO
   TS
2
IC50 = 144.31 nM
   TI
   LI
   LO
   TS