Brief Information of the Compound and Protein
Compound Name
2-bromo-6-(7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-ylamino)phenol
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Canonical SMILES
Oc1c(Br)cccc1Nc1ncnc2cc3OCCOc3cc12
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Compound Formula C16H12BrN3O3
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 505.1 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 729.1 nM
   TI
   LI
   LO
   TS