General Information of the Cell Line
Cell Line ID
CL000102
Cell Line Name
U-87MG ATCC
Synonyms
U-87MG
U-87 MG
U87 MG
U-87-MG
U87-MG
U87MG
U-87
U87
87 MG
87MG
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0022
Disease
Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01279, Adenosine receptor A3
 Protein Info 
Compound ID Compound Name Compound Formula
CP0376874
 Compound Info 
4-methoxy-N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide
   Show/Hide
C20H17N5O2
  1
1
IC50 = 0.061 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0383482
 Compound Info 
N-(2-methyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)benzamide
   Show/Hide
C19H15N5O
  1
1
IC50 = 0.74 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01494, Beta-2 adrenergic receptor
 Protein Info 
Protein ID: PT01013, C-X-C chemokine receptor type 2
 Protein Info 
Protein ID: PT01298, Cannabinoid receptor 1
 Protein Info 
Protein ID: PT00834, Cannabinoid receptor 2
 Protein Info 
Protein ID: PT05673, Cystine/glutamate transporter
 Protein Info 
Protein ID: PT01771, E3 ubiquitin-protein ligase Mdm2
 Protein Info 
Protein ID: PT00922, Epidermal growth factor receptor
 Protein Info 
Protein ID: PT00962, Glycogen synthase kinase-3 beta
 Protein Info 
Protein ID: PT01557, Indoleamine 2,3-dioxygenase 1
 Protein Info 
Protein ID: PT03341, Indoleamine 2,3-dioxygenase 2
 Protein Info 
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
 Protein Info 
Protein ID: PT03648, Isocitrate dehydrogenase [NADP], mitochondrial
 Protein Info 
Protein ID: PT01045, Phosphoinositide 3-kinase alpha
 Protein Info 
Protein ID: PT01241, Prolyl endopeptidase FAP
 Protein Info 
Protein ID: PT00845, RAC-alpha serine/threonine-protein kinase
 Protein Info 
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
 Protein Info 
Protein ID: PT02896, Tryptophan 2,3-dioxygenase
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0069210
 Compound Info 
US8569511, 1
   Show/Hide
 C22H20F2N6O2  1
1
IC50 = 7940 nM
   TI
   LI
   LO
   TS
CP0117454
 Compound Info 
2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)-N-methylbenzamide
   Show/Hide
 C23H25ClN6O3  1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0130706
 Compound Info 
N-[(3S,4S)-4-(3,4-difluorophenyl)piperidin-3-yl]-2-fluoro-4-(2-methylpyrazol-3-yl)benzamide;hydrochloride
   Show/Hide
 C22H22ClF3N4O  1
1
IC50 = 9260 nM
   TI
   LI
   LO
   TS
CP0140704
 Compound Info 
2-[[5-chloro-2-[4-[[[3,4-dioxo-2-[2-(prop-2-enoylamino)ethylamino]cyclobuten-1-yl]amino]methyl]anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
   Show/Hide
 C28H27ClN8O4  1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0214989
 Compound Info 
N-[2-(4-chlorophenyl)ethyl]-7-[(4-fluorophenyl)methyl]-2-methylsulfanylpyrrolo[2,3-d]pyrimidin-4-amine
   Show/Hide
 C22H20ClFN4S  1
1
IC50 = 46100 nM
   TI
   LI
   LO
   TS
CP0247131
 Compound Info 
7-[(4-fluorophenyl)methyl]-2-methylsulfanyl-N-(2-phenylethyl)pyrrolo[2,3-d]pyrimidin-4-amine
   Show/Hide
 C22H21FN4S  1
1
IC50 = 13300 nM
   TI
   LI
   LO
   TS
CP0262311
 Compound Info 
7-(2-chloro-2-phenylethyl)-2-methylsulfanyl-N-phenylpyrrolo[2,3-d]pyrimidin-4-amine
   Show/Hide
 C21H19ClN4S  1
1
IC50 = 27400 nM
   TI
   LI
   LO
   TS
CP0376874
 Compound Info 
4-methoxy-N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide
   Show/Hide
 C20H17N5O2  1
1
IC50 = 0.091 nM
   TI
   LI
   LO
   TS
CP0383482
 Compound Info 
N-(2-methyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)benzamide
   Show/Hide
 C19H15N5O  1
1
IC50 = 0.41 nM
   TI
   LI
   LO
   TS
CP0384379
 Compound Info 
1-(1,3-benzodioxol-5-ylmethyl)-3-hexylthiourea
   Show/Hide
 C15H22N2O2S  1
1
IC50 = 86950 nM
   TI
   LI
   LO
   TS
CP0422325
 Compound Info 
5,7-dimethoxy-3-[3-[2-[(1E,4E)-3-oxo-5-pyridin-2-ylpenta-1,4-dienyl]phenoxy]propoxy]-2-(3,4,5-trimethoxyphenyl)chromen-4-one
   Show/Hide
 C39H37NO10  1
1
IC50 = 3930 nM
   TI
   LI
   LO
   TS
CP0437299
 Compound Info 
N-[2-[2-[4-chloro-3-(trifluoromethyl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]-N-methylmethanesulfonamide
   Show/Hide
 C22H18ClF6N5O2S  1
1
GI50 > 30000 nM
   TI
   LI
   LO
   TS
CP0458290
 Compound Info 
N-methyl-N-[2-[5-(trifluoromethyl)-2-[4-(trifluoromethyl)anilino]pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]methanesulfonamide
   Show/Hide
 C22H19F6N5O2S  1
1
GI50 > 30000 nM
   TI
   LI
   LO
   TS
CP0465622
 Compound Info 
N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-[3-(4-fluorophenyl)-5-methylsulfanyl-1,2,4-triazol-4-yl]pyridin-2-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C28H31FN8OS  1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0474944
 Compound Info 
(2R,6S)-4-[6-(furan-2-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl]-2,6-dimethylmorpholine
   Show/Hide
 C20H24N4O3S  1
1
IC50 = 12800 nM
   TI
   LI
   LO
   TS
CP0509690
 Compound Info 
N-[2-[2-(4-chloro-2-methylanilino)-5-(trifluoromethyl)pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]-N-methylmethanesulfonamide
   Show/Hide
 C22H21ClF3N5O2S  1
1
GI50 = 28300 nM
   TI
   LI
   LO
   TS
CP0509692
 Compound Info 
N-[2-[2-(4-anilinoanilino)-5-(trifluoromethyl)pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]-N-methylmethanesulfonamide
   Show/Hide
 C27H25F3N6O2S  1
1
GI50 = 29800 nM
   TI
   LI
   LO
   TS
CP0517376
 Compound Info 
N-[3-[[4-[3-(4-fluorophenyl)-5-methylsulfanyl-1,2,4-triazol-4-yl]pyridin-2-yl]amino]phenyl]prop-2-enamide
   Show/Hide
 C23H19FN6OS  1
1
IC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0531340
 Compound Info 
N-[5-[[4-[3-(4-fluorophenyl)-5-methylsulfanyl-1,2,4-triazol-4-yl]pyridin-2-yl]amino]-4-methoxy-2-(4-morpholin-4-ylpiperidin-1-yl)phenyl]prop-2-enamide
   Show/Hide
 C33H37FN8O3S  1
1
IC50 = 15200 nM
   TI
   LI
   LO
   TS
CP0538413
 Compound Info 
N-[2-[2-(2-chloro-4-methylanilino)-5-(trifluoromethyl)pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]-N-methylmethanesulfonamide
   Show/Hide
 C22H21ClF3N5O2S  1
1
GI50 > 30000 nM
   TI
   LI
   LO
   TS
CP0540511
 Compound Info 
N-(6-fluoro-1,3-benzothiazol-2-yl)-1,3-diphenylpyrazole-4-carboxamide
   Show/Hide
 C23H15FN4OS  1
1
IC50 = 5570 nM
   TI
   LI
   LO
   TS
CP0551675
 Compound Info 
2-(dimethylamino)ethyl 4-[4-[[5-chloro-4-[2-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]benzoyl]piperazine-1-carbodithioate
   Show/Hide
 C28H33ClN8O2S2  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0554700
 Compound Info 
N-(6-fluoro-1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)-1-phenylpyrazole-4-carboxamide
   Show/Hide
 C23H14F2N4OS  1
1
IC50 = 12500 nM
   TI
   LI
   LO
   TS
CP0567484
 Compound Info 
N-[2-[2-(3,4-dimethylanilino)-5-(trifluoromethyl)pyrimidin-4-yl]-1,3-dihydroisoindol-4-yl]-N-methylmethanesulfonamide
   Show/Hide
 C23H24F3N5O2S  1
1
GI50 > 30000 nM
   TI
   LI
   LO
   TS
CP0577056
 Compound Info 
2-(dimethylamino)ethyl 4-[4-[[5-fluoro-4-[2-(methylcarbamoyl)anilino]pyrimidin-2-yl]amino]benzoyl]piperazine-1-carbodithioate
   Show/Hide
 C28H33FN8O2S2  1
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
CP0725696
 Compound Info 
N-[3-(2,5-Dimethoxybenzyloxy)-4-(methanesulfonylamino)-phenyl]-4-methoxybenzamide
   Show/Hide
 C24H26N2O7S  1
1
IC50 = 4.78 nM
   TI
   LI
   LO
   TS
CP0853900
 Compound Info 
(E)-4-(8-Triphenylphosphoniumoctyloxy)stilbene Iodide
   Show/Hide
 C40H42IOP  1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0906934
 Compound Info 
(E)-4-(7-Triphenylphosphoniumheptyloxy)stilbene Iodide
   Show/Hide
 C39H40IOP  1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0915199
 Compound Info 
(E)-(4-(4-(3,5-dimethoxystyryl)phenoxy)butyl)triphenylphosphonium iodide
   Show/Hide
 C38H38IO3P  1
1
IC50 = 860 nM
   TI
   LI
   LO
   TS
CP0945631
 Compound Info 
(E)-4-(3-Triphenylphosphoniumpropyloxy)stilbene Iodide
   Show/Hide
 C35H32IOP  1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line