Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-4-(dimethylamino)-N-[3-[4-(1H-indazol-3-ylamino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl]oxyphenyl]but-2-enamide
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 PubChem ID
CID: 122186152
Canonical SMILES
CN(C)C\C=C\C(=O)Nc1cccc(Oc2nc(Nc3n[nH]c4ccccc34)cc(n2)N2CCN(C)CC2)c1
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Compound Formula C28H33N9O2
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
2
IC50 = 3600 nM
   TI
   LI
   LO
   TS
3
IC50 = 6700 nM
   TI
   LI
   LO
   TS