Brief Information of the Compound and Protein
Compound Name
1-[4-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxypiperidin-1-yl]propan-1-one
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PubChem ID
CID: 168292989
Canonical SMILES
CCC(=O)N1CCC(CC1)Oc1nc(Nc2ccc(cc2)N2CCN(C)CC2)nc2ccsc12
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Compound Formula C25H32N6O2S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 267.54 nM
   TI
   LI
   LO
   TS
2
IC50 = 356.26 nM
   TI
   LI
   LO
   TS