Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(4-bromo-2-fluoroanilino)quinazolin-6-yl]prop-2-enamide
    Show/Hide
 PubChem ID
CID: 76325766
Canonical SMILES
Fc1cc(Br)ccc1Nc1ncnc2ccc(NC(=O)C=C)cc12
    Show/Hide
Compound Formula C17H12BrFN4O
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000157 NCI-H1975
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2.1 nM
   TI
   LI
   LO
   TS