Brief Information of the Compound and Protein
Compound Name
N-(3-ethynylphenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
    Show/Hide
PubChem ID
CID: 138513783
Canonical SMILES
C#Cc1cccc(Nc2ncnc3cc4OCCOc4cc23)c1
    Show/Hide
Compound Formula C18H13N3O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 48.7 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 59.8 nM
   TI
   LI
   LO
   TS