Brief Information of the Compound and Protein
| Compound Name |
4-hydroxy-3-[4-(pyrazin-2-ylmethylamino)quinazolin-2-yl]benzonitrile
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Epidermal growth factor receptor
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Protein Classification |
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
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| Uniprot ID | Gene Name | EGFR |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 2 |
| 1 |
IC50 = 38.7 nM
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TI
LI
LO
TS
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|---|---|---|---|
| 2 |
IC50 > 50000 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 17 nM | ||
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| 2 | IC50 = 17.9 nM | ||
| 3 | IC50 = 85.2 nM | ||
| 4 | IC50 = 367.1 nM | ||
| 5 | IC50 > 1000 nM | ||
| 6 | IC50 >= 50000 nM | ||
| 7 | IC50 > 50000 nM | ||