Brief Information of the Compound and Protein
Compound Name
(6E)-6-[4-(3-pyridinylmethylamino)-1H-quinazolin-2-ylidene]-1-cyclohexa-2,4-dienone
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PubChem ID
CID: 935994
Canonical SMILES
Oc1ccccc1-c1nc(NCc2cccnc2)c2ccccc2n1
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Compound Formula C20H16N4O
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 24300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 149 nM
2 IC50 = 24300 nM