Brief Information of the Compound and Protein
| Compound Name |
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Epidermal growth factor receptor
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Protein Classification |
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
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| Uniprot ID | Gene Name | EGFR |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 1 |
| 1 |
IC50 = 57 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 2.96 nM | ||
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| 2 | IC50 = 43.5 nM | ||
| 3 | IC50 = 57.8 nM | ||
| 4 | IC50 = 80 nM | ||
| 5 | IC50 = 110 nM | ||
| 6 | IC50 = 1150 nM | ||
| 7 | IC50 > 10000 nM | ||
| 8 | IC50 > 50000 nM | ||
| 9 | Kd > 10000 nM | ||