Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[4-(4-acetylpiperazin-1-yl)-6-(1H-indazol-3-ylamino)pyrimidin-2-yl]oxyphenyl]prop-2-enamide
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 PubChem ID
CID: 122186154
Canonical SMILES
CC(=O)N1CCN(CC1)c1cc(Nc2n[nH]c3ccccc23)nc(Oc2cccc(NC(=O)C=C)c2)n1
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Compound Formula C26H26N8O3
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
2
IC50 = 600 nM
   TI
   LI
   LO
   TS
3
IC50 = 3600 nM
   TI
   LI
   LO
   TS