Brief Information of the Compound and Protein
Compound Name
1-[4-(3-chloroanilino)quinazolin-6-yl]-3-(3,5-difluorophenyl)thiourea
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PubChem ID
CID: 137633148
Canonical SMILES
Fc1cc(F)cc(NC(=S)Nc2ccc3ncnc(Nc4cccc(Cl)c4)c3c2)c1
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Compound Formula C21H14ClF2N5S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 60.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 60.1 nM